patentstorm.us 258 85 http://www.patentstorm.us/ http://www.patentstorm.us/images/logo.gif PatentStorm -> Applications -> Organic compounds -- part of the class 532-570 series http://www.patentstorm.us/rss/class/applications/rss-549.xml Recent patent applications filings in USPTO Class 549 Organic compounds -- part of the class 532-570 series. Thu, 16 Feb 2012 15:00:55 patents@patentstorm.us en <![CDATA[COMPOSITIONS FOR LABELING AND IDENTIFYING AUTOPHAGOSOMES AND METHODS FOR MAKING AND USING THEM]]> http://www.patentstorm.us/applications/20120042398/description.html
  • Application Number:  20120042398
  • Publication Date:  2012-02-16
  • Inventors:  Gottlieb, Roberta A.; Cole, Thomas E.; Perry-Garza, Cynthia N.; Carreira, Raquel Sousa; Bartlett, Bryan J.; Finley, Kim
    • The invention provides methods and compositions for detecting and measuring the amount of autophagosomes in cells or tissues, including biopsy samples, in vitro, in situ and/or in vivo. By detecting and measuring the amount of autophagosomes in cells or tissues, the methods and compositions of the invention also measure the amount of autophagic activity in a cell or a tissue. In one aspect, the invention can be adapted to a plate-reader format for high-throughput screening of drugs that ...
    ]]>     20120042398     <![CDATA[TWO-STAGE CALCINATION FOR CATALYST PRODUCTION]]> http://www.patentstorm.us/applications/20120041217/description.html
  • Application Number:  20120041217
  • Publication Date:  2012-02-16
  • Inventors:  Allen, Stephen R.; Bhise, Vijay S.; Bortinger, Arie
    • The invention relates to an improved process for producing a catalyst useful for the epoxidation of ethylene to ethylene oxide. In forming the catalyst, a silver-impregnated support is subjected to two calcinations. The support is subjected to a first calcination in a first atmosphere comprising air. Next the support is subjected to a second calcination in a second atmosphere which is substantially entirely comprised of inert gas, and which second atmosphere is substantially absent of hydrogen. ...
    ]]>     20120041217     <![CDATA[METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS]]> http://www.patentstorm.us/applications/20120041216/description.html
  • Application Number:  20120041216
  • Publication Date:  2012-02-16
  • Inventors:  Skerra, Arne; Sieber, Volker; Haas, Thomas; Doderer, Kai; Grammann, Katrin; Ruehmann, Broder; Pfeffer, Jan Christoph; Rollmann, Claudia; Rausch, Christian; Lerchner, Alexandra
    • The invention relates to a method for the amination of at least one keto group in a multicyclic ring system comprising at least one keto group into an amino group, using at least one enzyme E having transaminase ...
    ]]>     20120041216     <![CDATA[PROTEASE INHIBITOR PRECURSOR SYNTHESIS]]> http://www.patentstorm.us/applications/20120041215/description.html
  • Application Number:  20120041215
  • Publication Date:  2012-02-16
  • Inventor:  LINCLAU, Bruno
    • The present invention provides a compound having the structure (I) and processes for the production thereof and the intermediates used in such process.

    ]]> 20120041215 <![CDATA[HEXAHYDRO ETHANOCHROMENES AND RELATED COMPOUNDS AND THEIR USE IN FRAGRANCE COMPOSITIONS]]> http://www.patentstorm.us/applications/20120041214/description.html

  • Application Number:  20120041214
  • Publication Date:  2012-02-16
  • Inventors:  Boden, Richard M.; Geng, Feng
    • The present invention relates to novel compounds and their use in fragrance compositions. Novel hexahydro ethanochromene and related hexahydro ethanochromane compounds of the present invention are represented by formula:

      • wherein R1 is hydrogen or methyl; R2 and R2′ are identical ...
        ]]> 20120041214 <![CDATA[4-(HETEROCYCLOALKYL) BENZENE -1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND ALSO IN COSMETICS]]> http://www.patentstorm.us/applications/20120041213/description.html
      • Application Number:  20120041213
      • Publication Date:  2012-02-16
      • Inventors:  Pascal, Jean-Claude; Boiteau, Jean-Guy
      4-(heterocycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below:

      Also described, are compositions including the same, processes for preparation thereof and to the use thereof in pharmaceutical or cosmetic compositions for use in the treatment or prevention of pigmentary ...
      ]]> 20120041213 <![CDATA[METHOD FOR PREPARING A DIALKYL CARBONATE OF DIANHYDROHEXITOL]]> http://www.patentstorm.us/applications/20120041169/description.html

    • Application Number:  20120041169
    • Publication Date:  2012-02-16
    • Inventors:  Arico, Fabio; Fuertes, Patrick; Ibert, Mathias; Josien, Emilie; Tundo, Pietro
    A method for preparing dialkyl carbonates of dianhydrohexitol, includes the following steps: (a) preparing an initial reaction mixture containing at least one dianhydrohexitol, at least two mole equivalents of a dialkyl carbonate of formula and a transesterification catalyst; (b) heating the reaction mixture to a temperature greater than or equal to the boiling temperature of the formed alcohol, or of the azeotrope thereof, in a reaction chamber preferably provided with a rectification column ...
    ]]>     20120041169     <![CDATA[Preparation of Cobaltocenium-Containing Monomers and Their Polymers]]> http://www.patentstorm.us/applications/20120041163/description.html
  • Application Number:  20120041163
  • Publication Date:  2012-02-16
  • Inventors:  Tang, Chuanbing; Ren, Lixia
    • Methods of forming a cobaltocenium-containing polymer are provided through polymerizing a plurality of cobaltocenium-containing monomers via controlled radical polymerization or controlled ring-opening polymerization. Each cobaltocenium-containing monomer comprises a cobaltocenium moiety covalently connected to a polymerizable group. Cobaltocenium-containing monomers are also provided that include a cobaltocenium moiety covalently connected to a polymerizable group. Cobaltocenium-containing ...
    ]]>     20120041163     <![CDATA[REGIOFUNCTIONAL CARBON NANOTUBE BEAM AND METHOD]]> http://www.patentstorm.us/applications/20120041153/description.html
  • Application Number:  20120041153
  • Publication Date:  2012-02-16
  • Inventor:  Nicholas, Nolan Walker
    • The present invention is generally directed toward a regiofunctional carbon nanotube beam structures and a method the same. The regiofunctional carbon nanotube beam structures contain chemical moieties attached selectively to the ends and/or the sidewalls of the nanotube which differentiate the physico-chemical properties of the nanotube ends from the physico-chemical of the sidewalls to enable directed self-assembly. The method comprises the steps including opening carbon nanotube ends, ...
    ]]>     20120041153     <![CDATA[POLYOL FORMED FROM AN EPOXIDIZED OIL]]> http://www.patentstorm.us/applications/20120041089/description.html
  • Application Number:  20120041089
  • Publication Date:  2012-02-16
  • Inventors:  Zhao, Cheng-Le; Kumar, Rajesh; Smiecinski, Theodore M.; Roh, Yeonsuk; Kaczan, David
    • A polyol includes the reaction product of an epoxidized oil and an organic acid. The epoxidized oil and the organic acid are reacted in the presence of a Lewis base catalyst including at least one of a phosphorous atom or a nitrogen atom. The polyol is formed by a method that includes the step of reacting the epoxidized oil with the organic acid in the presence of the Lewis base ...
    ]]>     20120041089     <![CDATA[NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION]]> http://www.patentstorm.us/applications/20120041046/description.html
  • Application Number:  20120041046
  • Publication Date:  2012-02-16
  • Inventors:  Guerrini, Andrea; Varchi, Greta; Tesei, Anna; Brigliadori, Giovanni
    • The present invention concerns compounds of general Formula (I): method of preparation and uses ...
    ]]>     20120041046     <![CDATA[AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS]]> http://www.patentstorm.us/applications/20120041039/description.html
  • Application Number:  20120041039
  • Publication Date:  2012-02-16
  • Inventors:  Hong, Feng; Scott, Ian L.; Orme, Mark W.; Little, JR., Thomas L.; Kuksa, Vladimir A.; Kubota, Ryo
    • Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and ...
    ]]>     20120041039     <![CDATA[AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS]]> http://www.patentstorm.us/applications/20120041038/description.html
  • Application Number:  20120041038
  • Publication Date:  2012-02-16
  • Inventors:  Hong, Feng; Scott, Ian L.; Orme, Mark W.; Little, JR., Thomas L.; Kuksa, Vladimir A.; Kubota, Ryo
    • Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and ...
    ]]>     20120041038     <![CDATA[SUBSTITUTED ACYLGUANIDINE DERIVATIVES (AS AMENDED)]]> http://www.patentstorm.us/applications/20120041036/description.html
  • Application Number:  20120041036
  • Publication Date:  2012-02-16
  • Inventors:  Kinoyama, Isao; Miyazaki, Takehiro; Koganemaru, Yohei; Washio, Takuya
    • An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on serotonin 5-HT5A receptor modulating action.

    It was discovered that acylguanidine derivatives, in which the guanidine is bonded to one ring of a naphthalene via a carbonyl group and a cyclic group is bonded to the other ring thereof, exhibit potent the 5-HT5A receptor modulating action and excellent pharmacological ...
    ]]> 20120041036 <![CDATA[Dihydrolipoic Acid Derivatives Comprising Nitric Oxide and Therapeutic Uses Thereof]]> http://www.patentstorm.us/applications/20120041025/description.html

  • Application Number:  20120041025
  • Publication Date:  2012-02-16
  • Inventor:  Parthasarathy, Sampath
    • Compounds are provided that comprise dinitroso-derivatives of dihydrolipoic acid. Pharmaceutical compositions comprising the compounds and methods of using the compounds for treating various diseases and disorders, including angina, hypertension, diabetes, dyslipidemia, renal insufficiency, myocardial infarction, stroke, atherosclerosis, and the target organ damage that accompanies these various diseases and disorders, are further provided. The compounds are useful in improving vasodilation, ...
    ]]>     20120041025     <![CDATA[11-Aza, 11-Thia and 11-Oxa Sterol Compounds and Compositions]]> http://www.patentstorm.us/applications/20120041016/description.html
  • Application Number:  20120041016
  • Publication Date:  2012-02-16
  • Inventor:  Frincke, James M.
    • The invention provides compositions comprising formula 1 steroids, e.g., 16α-bromo-3β-hydroxy-5α-androstan-17-one hemihydrate and one or more excipients, including compositions that comprise a liquid formulation comprising less than about 3% v/v water. The compositions are useful to make improved pharmaceutical formulations. The invention also provides methods of intermittent dosing of steroid compounds such as analogs of 16α-bromo-3β-hydroxy-5α-androstan-17-one and compositions useful in ...
    ]]>     20120041016     <![CDATA[SUBSTITUTED BENZOFUSED DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS]]> http://www.patentstorm.us/applications/20120041011/description.html
  • Application Number:  20120041011
  • Publication Date:  2012-02-16
  • Inventors:  GHARAT, Laxmikant Atmaram; JOSHI, Uday Mukund; KHAIRATKAR-JOSHI, Neelima; KADAM, Suresh Mahadev
    • The present invention relates to substituted benzofused derivatives, which can he used as vanilloid receptor ligands, method of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing ...
    ]]>     20120041011     <![CDATA[MIF MODULATORS]]> http://www.patentstorm.us/applications/20120040974/description.html
  • Application Number:  20120040974
  • Publication Date:  2012-02-16
  • Inventors:  Jorgensen, William L.; Bucala, Richard J.
    • The invention provides novel heterocyclic compounds, pharmaceutical compositions and methods of treatment that modulate levels of MIF expression and treat disorders associated with high or low levels of MIF ...
    ]]>     20120040974     <![CDATA[CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF]]> http://www.patentstorm.us/applications/20120040932/description.html
  • Application Number:  20120040932
  • Publication Date:  2012-02-16
  • Inventors:  Boyer, Serge; Dudley, Michael N.; Griffith, David C.; Totrov, Maxim; Hirst, Gavin; Reddy, Raja; Hecker, Scott; Rodny, Olga
    • Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic ...
    ]]>     20120040932     <![CDATA[NOVEL ORGANOPOLYSILOXANE AND COSMETIC CONTAINING THE SAME]]> http://www.patentstorm.us/applications/20120040931/description.html
  • Application Number:  20120040931
  • Publication Date:  2012-02-16
  • Inventor:  KAMEI, Masanao
    • There is disclosed an organopolysiloxane represented by the following general formula (1).

    (each R1 independently represents a group selected from an alkyl group having 1 to 30 carbon atoms, a fluorine-substituted alkyl group having 1 to 30 carbon atoms, an aryl group having 6 to 30 carbon atoms, and an aralkyl group having 6 to 30 carbon atoms; Y represents a polyvalent alcohol compound residue; M represents any of a ...
    ]]> 20120040931 <![CDATA[NOVEL HERBICIDES]]> http://www.patentstorm.us/applications/20120040826/description.html

  • Application Number:  20120040826
  • Publication Date:  2012-02-16
  • Inventors:  Mathews, Christopher John; Smith, Steve; Taylor, John Benjamin; Jeanmart, Stephane André Marie
    • Bicyclic dione compounds, and derivatives thereof, which are suitable for use as herbicides.

    ]]> 20120040826 <![CDATA[CONTRAST AGENTS]]> http://www.patentstorm.us/applications/20120039815/description.html

  • Application Number:  20120039815
  • Publication Date:  2012-02-16
  • Inventor:  Priebe, Hanno
    • The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two linked iodinated phenyl groups of the general formula R—N(CO—CH3)XN(CO—CH3)—R and salts or optical active isomers thereof, wherein X denotes a divalent linking moiety with 5 to 10 bridge elements of carbon, oxygen, ...
    ]]>     20120039815     <![CDATA[NOVEL CYCLOALKENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICES USING THE SAME]]> http://www.patentstorm.us/applications/20120037892/description.html
  • Application Number:  20120037892
  • Publication Date:  2012-02-16
  • Inventors:  Bae, Jae-Soon; Kim, Seong-So; Lee, Jae-Chol; Jang, Hye-Young; Kim, Jeung-Gon; Kim, Chang-Hwan
    • The present invention relates to a novel cycloalkene derivative, and an organic electronic device using the same. The cycloalkene derivative according to the exemplary embodiment of the present invention may act as a hole injection, a hole transport, an electron injection, an electron transport, or a light emitting material in an organic light emitting diode and an organic electronic device, and in particular, may be used alone as a light emitting host or a ...
    ]]>     20120037892     <![CDATA[PROCESS FOR PREPARING ALLYL ALCOHOL ALKOXYLATES]]> http://www.patentstorm.us/applications/20120035381/description.html
  • Application Number:  20120035381
  • Publication Date:  2012-02-09
  • Inventors:  Ostrowski, Thomas; Zipplies, Matthias; KLUMPE, Markus
    • A process for preparing polyether alcohols by reacting one or more unsaturated starters having at least one active hydrogen atom per molecule with one or more alkylene oxides in the liquid phase in the presence of a basic catalyst in a reactor, wherein the one or more alkylene oxides are introduced into the reactor in such a way that the concentration of unreacted alkylene oxide in the liquid reaction mixture in the reactor is increased as far as possible with increasing degree of addition of ...
    ]]>     20120035381     <![CDATA[PROCESS FOR PREPARING EPICHLOROHYDRIN FROM GLYCEROL]]> http://www.patentstorm.us/applications/20120035380/description.html
  • Application Number:  20120035380
  • Publication Date:  2012-02-09
  • Inventor:  Kanzler, Walter
    • A process for preparing epichlorohydrin includes chlorinating glycerol with gaseous hydrogen chloride in a bubble column, by supplying hydrogen chloride, glycerol and a mixture of monochloropropanediol and residues of glycerol recycled from the distillation units connected downstream of the bubble column, dichloropropanol and residues to the bottom of the bubble column, and, close to the top of the bubble column, drawing off the mixture of monochloropropanediol, dichloropropanol, water, ...
    ]]>     20120035380     <![CDATA[METHOD FOR PREPARING TAXANE DERIVATIVES]]> http://www.patentstorm.us/applications/20120035379/description.html
  • Application Number:  20120035379
  • Publication Date:  2012-02-09
  • Inventors:  Choi, Ho-Joon; Cho, Jin-Suk; Pyo, Sang-Hyun; Kim, Moon-Suk; Song, Jai-Young
    • Provided is a method for preparing a taxane derivative, comprising: carrying out condensation of a phenylisoserine derivatives having a protective group introduced thereto or a mixture of isomers thereof, as a side chain, with a baccatin III derivative or 10-deacetyl-baccatin III derivative to obtain a mixture of isomers; separating the isomers via chromatography; and carrying out a reversion of the stereochemical structure of a selectively separated isomer, which is suitable for producing a ...
    ]]>     20120035379     <![CDATA[HYDROGENATION PROCESS FOR THE PREPARATION OF TETRAHYDROFURAN AND ALKYLATED DERIVATIVES THEREOF]]> http://www.patentstorm.us/applications/20120035378/description.html
  • Application Number:  20120035378
  • Publication Date:  2012-02-09
  • Inventors:  Sengupta, Sourav Kumar; Hutchenson, Keith W.
    • A process is provided for the synthesis of tetrahydrofuran and related compounds by hydrogenation of furan and derivatives, using a sponge nickel catalyst that has been promoted with iron and ...
    ]]>     20120035378     <![CDATA[ORGANOPHOSPHORUS COMPOUNDS, CATALYTIC SYSTEMS COMPRISING SAID COMPOUNDS AND METHOD OF HYDROCYANATION OR OF HYDROFORMYLATION USING SAID CATALYTIC SYSTEMS]]> http://www.patentstorm.us/applications/20120035377/description.html
  • Application Number:  20120035377
  • Publication Date:  2012-02-09
  • Inventors:  Mastroianni, Sergio; Mikhel, Igor; Pringle, Paul
    • Organophosphorus compounds, catalytic systems comprising a metallic element forming a complex with the organophosphorus compounds and methods of hydrocyanation and of hydroformylation employed in the presence of the catalytic systems are ...
    ]]>     20120035377     <![CDATA[METHODS FOR THE MANUFACTURE OF ACETALS AND KETALS, AND THE ACETALS AND KETALS PRODUCED THEREBY]]> http://www.patentstorm.us/applications/20120035376/description.html
  • Application Number:  20120035376
  • Publication Date:  2012-02-09
  • Inventors:  Badarinarayana, Vivek; Jing, Feng; Mullen, Brian D.; Scholten, Marc D.; Louwagie, Andrew J.; Donen, Steven A.
    • A method for producing a product that comprises glycerol ketal of ethyl levulinate or propylene glycol ketal of ethyl levulinate comprises reacting either glycerol or propylene glycol with ethyl levulinate in the presence of a homogenous or heterogeneous catalyst system in a reactor system. The ethyl levulinate and either glycerol or propylene glycol are heated to remove water, polyol, and excess ethyl levulinate. The excess ethyl levulinate and polyol is recycled back to the reactor. The ...
    ]]>     20120035376     <![CDATA[DI-TIN FUSED THIOPHENE COMPOUNDS AND POLYMERS AND METHODS OF MAKING]]> http://www.patentstorm.us/applications/20120035375/description.html
  • Application Number:  20120035375
  • Publication Date:  2012-02-09
  • Inventors:  Niu, Weijun; He, Mingqian
    • Di-tin fused thiophene (FT) compounds, FT polymers, such as of the formula -{-(FTx)-(Ar)m-}n-, FT polymer containing articles or devices, and methods for making and using the FT compounds and polymers thereof of the formulas, as defined ...
    ]]>     20120035375     <![CDATA[PROCESS FOR THE MANUFACTURE OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF]]> http://www.patentstorm.us/applications/20120035371/description.html
  • Application Number:  20120035371
  • Publication Date:  2012-02-09
  • Inventor:  SCHWEIZER, Steffen
    • The current invention describes novel chiral synthetic routes and intermediates for the manufacture of chiral anti-inflammatory agents of general formula VIII

    in which at least one of the groups X1, X2, X3 is selected from

    • fluoro, chloro, bromo, hydroxy, methoxy, ethoxy, trifluoromethyl, amino
    • ]]> 20120035371 <![CDATA[TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME]]> http://www.patentstorm.us/applications/20120035364/description.html
    • Application Number:  20120035364
    • Publication Date:  2012-02-09
    • Inventors:  Sagisaka, Toshiya; Matsumoto, Shinji; Mohri, Masataka; Kato, Takuji; Yamamoto, Satoshi; Goto, Daisuke; Okada, Takashi; Shinoda, Masato
    A tetrathiafulvalene derivative expressed by General Formula (I): General Formula (I) in General Formula (I), X represents an atom selected from a carbon atom, a sulfur atom, and a nitrogen atom, and Xs may be the same or different; provided that when X is the carbon atom or the nitrogen atom, R1 to R8 each represent one of a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, and a substituted or ...
    ]]>     20120035364     <![CDATA[SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST)]]> http://www.patentstorm.us/applications/20120035361/description.html
  • Application Number:  20120035361
  • Publication Date:  2012-02-09
  • Inventors:  Bunch, Lennart; Jensen, Anders Asbjørn
    • The invention is the discovery of the use of the class of compounds represented by Formula I, as selective inhibitors of excitatory amino acid transporter (EAAT) subtype 1 (EAAT1) and its rodent ortholog L-glutamate/L-aspartate transporter (GLAST) for the study of function and distribution of EAAT1/GLAST in the central nervous system and studies of the physiological and pathological functions of the EAAT1/GLAST subtype in native tissues, cultured neurons, and/or animal models for CNS ...
    ]]>     20120035361     <![CDATA[METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN]]> http://www.patentstorm.us/applications/20120035304/description.html
  • Application Number:  20120035304
  • Publication Date:  2012-02-09
  • Inventors:  Uchiyama, Yohei; Ikoma, Reira; Iwasaki, Shohei
    • A method for inhibiting the crystal growth rate of an amide compound present in a molten polyolefin-based resin and a method for producing a polyolefin-based resin molded article are provided.

    A phenol compound is incorporated into an amide compound-containing polyolefin-based resin such that a weight ratio, amide compound:phenol compound, is 60:40 to ...
    ]]> 20120035304 <![CDATA[Histone Deacetylase Inhibitors]]> http://www.patentstorm.us/applications/20120035257/description.html

  • Application Number:  20120035257
  • Publication Date:  2012-02-09
  • Inventors:  Lan-Hargest, Hsuan-Yin; Kaufman, Robert J.; Wiech, Norbert L.
    • Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a hydroxamic acid group or a carboxylic acid group, can inhibit histone deacetylase. Histone deacetylase can repress gene expression, including expression of genes related to tumor suppression. Accordingly, inhibition of histone deacetylase can provide an alternate route for treating cancer, hematological disorders, e.g., hemoglobinopathies, and genetic related ...
    ]]>     20120035257     <![CDATA[DERIVATIVE OF [(3-HYDROXY-4 PYRON-2-YL)-METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS]]> http://www.patentstorm.us/applications/20120035255/description.html
  • Application Number:  20120035255
  • Publication Date:  2012-02-09
  • Inventors:  Fanelli, Mirco; Fusi, Vieri
    • The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases.

    ]]> 20120035255 <![CDATA[CRYSTALLINE FORMS OF GENISTEIN]]> http://www.patentstorm.us/applications/20120035253/description.html

  • Application Number:  20120035253
  • Publication Date:  2012-02-09
  • Inventors:  Berkenstam, Anders; Lorimer, Keith; Rehnmark, Stefan; Witt, Michael-Robin; Watt, Stephen
    • The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline genistein potassium salt dihydrate; crystalline genistein calcium salt; crystalline genistein magnesium salt; crystalline genistein L-lysine salt; crystalline genistein N-methylglucamine salt; crystalline genistein N-ethylglucamine salt; crystalline genistein diethylamine salt; and crystalline genistein monohydrate. The disclosure also ...
    ]]>     20120035253     <![CDATA[THIOPHENE INHIBITORS OF IKK-B SERINE-THREONINE PROTEIN KINASE]]> http://www.patentstorm.us/applications/20120035251/description.html
  • Application Number:  20120035251
  • Publication Date:  2012-02-09
  • Inventors:  Drummond, Alan Hastings; Testar, Richard James
    • The invention provides a compound which is (a) a thiophene carboxamide derivative of formula (IA) or (IB), or a tautomer thereof; or (b) a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof, wherein L1, A1 and W are as defined herein. The compounds are useful as IKKβ inhibitors. The compounds can thus be used in medicine, for example in the treatment of autoimmune and inflammatory diseases.

    ]]> 20120035251 <![CDATA[PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING]]> http://www.patentstorm.us/applications/20120035250/description.html

  • Application Number:  20120035250
  • Publication Date:  2012-02-09
  • Inventors:  Goodenowe, Dayan; Khan, M. Amin; Wood, Paul L.; Mankidy, Rishikesh; Ahiahonu, Pearson
    • Described herein are routes of synthesis and therapeutic uses of 1-alkyl, 2-acyl glycerol derivatives of formula I: which when administered to mammalian biological systems result in increased cellular concentrations of specific sn-2 substituted ethanolamine plasmalogens independent of the ether lipid synthesis capacity of the system. Elevating levels of the specific sn-2 substituted species in this way can cause lowering of membrane cholesterol levels and the lowering of amyloid secretion. ...
    ]]>     20120035250     <![CDATA[PREPARATION AND APPLICATION OF NOVEL ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES]]> http://www.patentstorm.us/applications/20120035206/description.html
  • Application Number:  20120035206
  • Publication Date:  2012-02-09
  • Inventors:  Yang, Chunliu; Yang, Gengliang; Ma, Zhengyue; Tian, Wei; Fang, Baoling; Wang, Ge; Li, Linbo; Bai, Ligai
    • Novel antibiotic and anticancer compounds of formula I, II, III, IV, derivatives, ostereoisomer, racemic and noracemic mixture of ostereoisomer, or the pharmaceutically acceptable salts or solvates of these compounds are disclosed. The preparation, pharmaceutical composition and biological activity of these compounds are disclosed.

    ]]> 20120035206 <![CDATA[GRISEOFULVIN ANALOGUES FOR THE TREATMENT OF CANCER BY INHIBITION OF CENTROSOMAL CLUSTERING]]> http://www.patentstorm.us/applications/20120035200/description.html

  • Application Number:  20120035200
  • Publication Date:  2012-02-09
  • Inventors:  Leber, Blanka; Kraemer, Alwin; Clausen, Mads; Larsen, Thomas; Roennest, Mads; Worm, Kasper
    • The invention relates to compounds of the formula (I), where the symbols have the meaning given in the specification, for use in a method for treating cancer, to use of these compounds for the manufacture of a pharmaceutical composition for the treatment of cancer, and to methods of treatment for said diseases employing a compound of formula (I).

    ]]> 20120035200 <![CDATA[CARBOXYLIC ACID COMPOUND]]> http://www.patentstorm.us/applications/20120035196/description.html

  • Application Number:  20120035196
  • Publication Date:  2012-02-09
  • Inventors:  Watanabe, Hideyuki; Ohnuki, Kei; Urano, Yasuharu; Kuramoto, Kazuyuki; Yonetoku, Yasuhiro; Negoro, Kenji
    • [Problem]

    The present invention has an object to provide a compound having a GPR40 agonistic activity, which is useful as a pharmaceutical composition, an insulin secretion promoter, or an agent for preventing/treating diabetes.

    [Means for Solution]

    The present inventors have extensively studied a compound having a GPR40 agonistic activity, and as a result, they have found that the compound (I) of the ...
    ]]> 20120035196 <![CDATA[Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents]]> http://www.patentstorm.us/applications/20120035175/description.html

  • Application Number:  20120035175
  • Publication Date:  2012-02-09
  • Inventors:  VITT, Daniel; AMMENDOLA, Aldo; DIEDERICHS, Julia; LEBAN, Johann
    • The present invention relates to a salt selected from the group comprising the N-methyl-D-glucamine salt (NMG), the diethylamine salt (DEA) salt, the magnesium salt, the tromethamine salt, the choline salt, the L-arginine salt, the zinc salt, and the 4-(2-hydroxyethyl)morpholine (HEM) salt of compounds of the general formula (I)

      • ]]> 20120035175 <![CDATA[NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES]]> http://www.patentstorm.us/applications/20120035170/description.html
      • Application Number:  20120035170
      • Publication Date:  2012-02-09
      • Inventors:  Megens, Antonius Adrianus Hendrikus Petrus; Trabanco-Suárez, Andrés Avelino; Núñez, José Maria
      This invention concerns novel substituted unsaturated tetracyclic tetrahydrofuran derivatives with binding affinities towards serotonine receptors, in particular 5-HT2A and 5-HT2C receptors, and towards dopamine receptors, in particular dopamine D2 receptors and with norepinephrine reuptake inhibition properties, pharmaceutical compositions comprising the compounds according to the invention, the use thereof as a medicine, in particular for the prevention and/or treatment ...
      ]]> 20120035170 <![CDATA[Prokineticin Receptor Antagonists And Uses Thereof]]> http://www.patentstorm.us/applications/20120035149/description.html
    • Application Number:  20120035149
    • Publication Date:  2012-02-09
    • Inventors:  Zhou, Qun-Yong; Li, Jia-Da; Huang, Qi
    Contemplated compounds, compositions, and methods of prokineticin antagonists are presented where a prokineticin antagonist is used in the treatment and prevention of various conditions and disorders, and especially type II ...
    ]]>     20120035149     <![CDATA[POLYMORPHS OF DARUNAVIR]]> http://www.patentstorm.us/applications/20120035142/description.html
  • Application Number:  20120035142
  • Publication Date:  2012-02-09
  • Inventor:  Marom, Ehud
    • The present invention provides new pseudopolymorphic forms of darunavir as well as a novel amorphous form of darunavir, pharmaceutical compositions comprising these compounds, methods for their preparation and use thereof in treating retroviral infections, in particular, HIV ...
    ]]>     20120035142     <![CDATA[GAMMA-AMINO-BUTYRIC ACID DERIVATIVES AS GABAB RECEPTOR LIGANDS]]> http://www.patentstorm.us/applications/20120035139/description.html
  • Application Number:  20120035139
  • Publication Date:  2012-02-09
  • Inventors:  Phan, Thu; Xu, Feng; Peng, Ge; Wustrow, David J.; Gallop, Mark A.; Dilip, Usha
    • Gamma-amino-butyric acid derivatives that are GABAB receptor ligands, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives and pharmaceutical compositions thereof for treating diseases are ...
    ]]>     20120035139     <![CDATA[Isosorbide Monoesters And Their Use In Household Applications]]> http://www.patentstorm.us/applications/20120035090/description.html
  • Application Number:  20120035090
  • Publication Date:  2012-02-09
  • Inventors:  Nieendick, Claus; Behler, Ansgar; Weuthen, Manfred; Alexandre, Teresa; Breffa, Catherine; Beckedahl, Burkhard; Dierker, Markus; Both, Sabine; Löh, Thorsten
    • Isosorbide monoesters according to the general formula (I) wherein R′ or R″ represent a hydrogen atom, or an group CO—R′″, with the proviso that one group R′ or R″ is a hydrogen atom, and R′″ represents linear or branched, saturated or unsaturated alkyl- or alkenyl groups with 6 to 22 C-atoms are useful compounds in the preparation of all kind of detergents, in particular dish washing detergents or of cosmetic preparations.

    ]]> 20120035090 <![CDATA[NOVEL HERBICIDES]]> http://www.patentstorm.us/applications/20120035053/description.html

  • Application Number:  20120035053
  • Publication Date:  2012-02-09
  • Inventors:  Mathews, Christopher John; Tyte, Melloney; Robinson, Louisa; Clough, John Martin; Beautement, Kevin; Jeanmart, Stephane André Marie
    • Cyclohexanedione compounds, which are suitable for use as herbicides.

    ]]> 20120035053 <![CDATA[DIAMOND PARTICLES HAVING ORGANIC COMPOUNDS ATTACHED THERETO, COMPOSITIONS THEREOF, AND RELATED METHODS]]> http://www.patentstorm.us/applications/20120034464/description.html

  • Application Number:  20120034464
  • Publication Date:  2012-02-09
  • Inventors:  Agrawal, Gaurav; DiGiovanni, Anthony A.; Chakraborty, Soma
    • A substance includes diamond particles having a maximum linear dimension of less than about 1 μm and an organic compound attached to surfaces of the diamond particles. The organic compound may include a surfactant or a polymer. A method of forming a substance includes exposing diamond particles to an organic compound, and exposing the diamond particles in the presence of the organic compound to ultrasonic energy. The diamond particles may have a maximum linear dimension of less than about 1 ...
    ]]>     20120034464