patentstorm.us 258 85 http://www.patentstorm.us/ http://www.patentstorm.us/images/logo.gif PatentStorm -> Applications -> Organic compounds -- part of the class 532-570 series http://www.patentstorm.us/rss/class/applications/rss-548.xml Recent patent applications filings in USPTO Class 548 Organic compounds -- part of the class 532-570 series. Thu, 16 Feb 2012 15:01:25 patents@patentstorm.us en <![CDATA[PROCESS FOR THE PREPARATION OF PREGABALIN]]> http://www.patentstorm.us/applications/20120041212/description.html
  • Application Number:  20120041212
  • Publication Date:  2012-02-16
  • Inventors:  Divi, Murali Krishna Prasad; Padakandla, Gundu Rao; Rao, Mysore Aswatha Narayana; Kuduva, Srinivasan Subramanian
    • The present invention provides a new enantioselective method of preparing (S)-3-(aminomethyl)-5-methylhexanoic acid, commonly known as pregabalin. The invention also provides new chiral intermediates useful in the production of ...
    ]]>     20120041212     <![CDATA[NOVEL PROCESS FOR PREPARING CARBOXY-CONTAINING PYRAZOLEAMIDO COMPOUNDS 597]]> http://www.patentstorm.us/applications/20120041211/description.html
  • Application Number:  20120041211
  • Publication Date:  2012-02-16
  • Inventors:  Rangappa, Paramashivappa; Kumar, Sythana Suresh; Kumar, Vinod Ch
    • A process for preparing pharmaceutically acceptable compounds of formula (I)

    wherein R1, R2, R3, X, A and Y are as defined in the specification is described and claimed, together with processes for preparing some key intermediates and products obtained ...
    ]]> 20120041211 <![CDATA[IM-20 CRYSTALLINE SOLID AND PROCESS FOR ITS PREPARATION]]> http://www.patentstorm.us/applications/20120041210/description.html

  • Application Number:  20120041210
  • Publication Date:  2012-02-16
  • Inventors:  Patarin, Joel; Caullet, Philippe; Paillaud, Jean-Louis; Lorgouilloux, Yannick; Dodin, Mathias; Bats, Nicolas
    • The invention concerns a crystalline solid designated IM-20 which has the X-ray diffraction diagram given below. Said solid has a chemical composition expressed by the empirical formula: mXO2: nGeO2: pZ2O3: qR: sF: wH2O, in which R represents one or more organic species, X represents one or more tetravalent element(s) other than germanium, Z represents at least one trivalent element and F is ...
    ]]>     20120041210     <![CDATA[Compound]]> http://www.patentstorm.us/applications/20120041207/description.html
  • Application Number:  20120041207
  • Publication Date:  2012-02-16
  • Inventors:  Vicker, Nigel; Potter, Barry Victor Lloyd; Ganeshapillai, Dharshini; Xiangdong, Su; Reed, Michael John; Purohit, Atul
    • A compound having Formula I

    wherein one of R1 and R2 is a group of the formula

    wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group

    ]]> 20120041207 <![CDATA[PREPARATION OF DIHYDROPYRROL DERIVATIVES AS INTERMEDIATES]]> http://www.patentstorm.us/applications/20120041205/description.html

  • Application Number:  20120041205
  • Publication Date:  2012-02-16
  • Inventors:  Waldmeier, Pius; Pfleger, Christophe; Spurr, Paul; Wang, Shaoning; Trussardi, Rene
    • The invention is concerned with a new scalable process for the preparation of compounds of formula I comprising a new process for the preparation of the key intermediate, a dihydropyrrole derivative formula II or a salt thereof.

    ]]> 20120041205 <![CDATA[METHOD FOR PRODUCING FLUORINE-CONTAINING POLYETHER CARBOXYLIC ACID AMIDE]]> http://www.patentstorm.us/applications/20120041201/description.html

  • Application Number:  20120041201
  • Publication Date:  2012-02-16
  • Inventors:  Kokin, Keisuke; Abe, Hideki; Takahashi, Yusuke; Murata, Seiichiro
    • A fluorine-containing polyether carboxylic acid amide represented by the general formula: CnF2n+1O(C3F6O)mRfCONHAr, wherein Rf is a fluorocarbon group having 1 to 2 carbon atoms, Ar is a nitrogen-containing heterocyclic group, n is an integer of 1 to 3, and m is an integer of 10 to 30, is produced by reacting a fluorine-containing polyether carboxylic acid fluoride represented by the general formula: ...
    ]]>     20120041201     <![CDATA[Process for the Preparation of Doxazosin and Salts Thereof]]> http://www.patentstorm.us/applications/20120041199/description.html
  • Application Number:  20120041199
  • Publication Date:  2012-02-16
  • Inventors:  Kankan, Rajendra Narayanrao; Rao, Dharmaraj Ramachandra; Birari, Dilip Ramdas
    • The present invention relates to a process for the preparation of doxazosin or salts ...
    ]]>     20120041199     <![CDATA[Proteasome Inhibitors and Methods of Using the Same]]> http://www.patentstorm.us/applications/20120041196/description.html
  • Application Number:  20120041196
  • Publication Date:  2012-02-16
  • Inventors:  De Munari, Sergio; D'Arasmo, Germano; Menta, Ernesto; Bernardini, Raffaella; Bernareggi, Alberto; Chatterjee, Sankar; Oliva, Ambrogio; Iqbal, Mohamed; Ferretti, Edmondo; Cassará, Paolo G.; Messina McLaughlin, Patricia A.
    • The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome ...
    ]]>     20120041196     <![CDATA[SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES]]> http://www.patentstorm.us/applications/20120041193/description.html
  • Application Number:  20120041193
  • Publication Date:  2012-02-16
  • Inventors:  Mokri, Homayoun H.; Cefalo, Dustin R.; Math, Shivanand K.; LaMunyon, James B.; Testa, Charles A.
    • Disclosed herein are vinyl-bromides, vinyl-boronic acids and vinyl-boronic acid derivatives useful as synthetic intermediates for the preparation of therapeutic agents. Also disclosed are methods of synthesis of vinyl-bromides, vinyl-boronic acids and vinyl-boronic acid ...
    ]]>     20120041193     <![CDATA[PHOSPHINATE RUTHENIUM COMPLEXES]]> http://www.patentstorm.us/applications/20120041191/description.html
  • Application Number:  20120041191
  • Publication Date:  2012-02-16
  • Inventors:  Parsy, Christophe Claude; Alexandre, Francois-Rene; Surleraux, Dominique; Bonnaterre, Florence Marie-Emilie
    • Provided herein are ruthenium complexes of Formula (I), and processes of preparation thereof. Also provided are methods of their use as a metathesis catalyst.

    ]]> 20120041191 <![CDATA[Coenzyme Q10 Nanoparticles, Preparation Method Thereof and Composition Containing Said Nanoparticles]]> http://www.patentstorm.us/applications/20120041178/description.html

  • Application Number:  20120041178
  • Publication Date:  2012-02-16
  • Inventors:  Chung, Bong Hyun; Han, Jung Hyun
    • Provided are a coenzyme Q10 nanoparticle, a method of preparing the same and a composition having the nanoparticle. According to the present invention, Coenzyme Q10 may be dissolved in only a water-miscible organic solvent, and easily made into a nano-sized particle and solubilized under a low energy condition, for example, by simple stirring. The coenzyme Q10 may be dispersion-stabilized by an amino acid or protein. The coenzyme Q10 is formed in a nano-sized particle and solubilized, an ...
    ]]>     20120041178     <![CDATA[Preparation of Cobaltocenium-Containing Monomers and Their Polymers]]> http://www.patentstorm.us/applications/20120041163/description.html
  • Application Number:  20120041163
  • Publication Date:  2012-02-16
  • Inventors:  Tang, Chuanbing; Ren, Lixia
    • Methods of forming a cobaltocenium-containing polymer are provided through polymerizing a plurality of cobaltocenium-containing monomers via controlled radical polymerization or controlled ring-opening polymerization. Each cobaltocenium-containing monomer comprises a cobaltocenium moiety covalently connected to a polymerizable group. Cobaltocenium-containing monomers are also provided that include a cobaltocenium moiety covalently connected to a polymerizable group. Cobaltocenium-containing ...
    ]]>     20120041163     <![CDATA[THERMOSETTING RING-OPENING METATHESIS POLYMERIZATION MATERIALS WITH THERMALLY DEGRADABLE LINKAGES]]> http://www.patentstorm.us/applications/20120041137/description.html
  • Application Number:  20120041137
  • Publication Date:  2012-02-16
  • Inventors:  Musa, Osama M.; Khosravi, Ezat
    • The present invention provides a new class of thermosetting ring-opening metathesis polymerization materials based on norbornene and oxanorbornene dicarboximide moieties containing at least one acetal ester group linkage. The acetal ester group is degradable when subjected to heat or acidic aqueous hydrolysis. The polymerization materials can be used in reworkable thermosetting compositions. R1-Rs, X, and n are defined herein.

    ]]> 20120041137 <![CDATA[USE OF PHARMACEUTICAL COMPOSITIONS CONTAINING MESEMBRENONE]]> http://www.patentstorm.us/applications/20120041045/description.html

  • Application Number:  20120041045
  • Publication Date:  2012-02-16
  • Inventors:  Gericke, Nigel; Harvey, Alan; Viljoen, Alvaro
    • The use of mesembrenone and medicaments and dietary supplements containing mesembrenone. The applicant has surprisingly found that mesembrenone exhibits potent PDE-4 inhibition properties and, in addition to being useful in treating conditions that respond to treatment with a PDE-4 inhibitor, has dual activity on account of its serotonin-uptake inhibition properties. Mesembrenone is extracted and isolated, for example as a pure compound, from plant material of the plant family ...
    ]]>     20120041045     <![CDATA[PROCESS FOR THE PREPARATION OF CARVEDILOL AND ITS ENANTIOMERS]]> http://www.patentstorm.us/applications/20120041044/description.html
  • Application Number:  20120041044
  • Publication Date:  2012-02-16
  • Inventors:  Marquillas Olondriz, Francisco; Munoz Alvarez, Anna; Pomares Marco, Marta; Trepat Guixer, Elisenda
    • The present invention relates to a process for the preparation of carvedilol as well as of the optically active R and S enantiomers thereof and of mixtures of these enantiomers and, more particularly, relates to an improved process for the preparation of carvedilol and its enantiomers characterized by the use of ethyl acetate as reaction ...
    ]]>     20120041044     <![CDATA[Sulfonamide Compounds for the Treatment of Respiratory Disorders]]> http://www.patentstorm.us/applications/20120041043/description.html
  • Application Number:  20120041043
  • Publication Date:  2012-02-16
  • Inventors:  Fox, Craig; Finch, Harry; Ramdas, Vidya
    • Compounds of formula (I) are agonists of PPARγ, useful for the treatment of respiratory disease; formula (I): wherein R1, R2 or R3 each independently represents halo, cyano, nitro, amino, alkyl, haloalkyl, alkoxy, haloalkoxy, carboxylic acid or an ester or amide thereof; R4 represents hydrogen or alkyl; m, n or p independently represents 0, 1, 2 or 3.

    ]]> 20120041043 <![CDATA[5-HYDROXY-BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY]]> http://www.patentstorm.us/applications/20120041041/description.html

  • Application Number:  20120041041
  • Publication Date:  2012-02-16
  • Inventor:  FAIRHURST, Robin Alec
    • Compounds of formula (I) in free or salt or solvate form, wherein T has the meaning as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the β2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

    ]]> 20120041041 <![CDATA[FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF]]> http://www.patentstorm.us/applications/20120041040/description.html

  • Application Number:  20120041040
  • Publication Date:  2012-02-16
  • Inventors:  Marr, Brian; Musa, Osama M.
    • The present invention provides novel functionalized mixtures 4- and 5-vinyl substituted regioisomers of 1,2,3-triazoles via 1,3-dipolar cycloaddition. Functionalized alkyne moieties with a terminal alcoholic functionality are reacted with functionalized organic moieties with a terminal leaving group and an azide to provide an alcoholic functionalized mixture of 4- and 5-substituted regioisomers of 1,2,3-triazole moieties. The mixture may be converted to a wide variety of useful functionalized ...
    ]]>     20120041040     <![CDATA[SUBSTITUTED ACYLGUANIDINE DERIVATIVES (AS AMENDED)]]> http://www.patentstorm.us/applications/20120041036/description.html
  • Application Number:  20120041036
  • Publication Date:  2012-02-16
  • Inventors:  Kinoyama, Isao; Miyazaki, Takehiro; Koganemaru, Yohei; Washio, Takuya
    • An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on serotonin 5-HT5A receptor modulating action.

    It was discovered that acylguanidine derivatives, in which the guanidine is bonded to one ring of a naphthalene via a carbonyl group and a cyclic group is bonded to the other ring thereof, exhibit potent the 5-HT5A receptor modulating action and excellent pharmacological ...
    ]]> 20120041036 <![CDATA[Dihydrolipoic Acid Derivatives Comprising Nitric Oxide and Therapeutic Uses Thereof]]> http://www.patentstorm.us/applications/20120041025/description.html

  • Application Number:  20120041025
  • Publication Date:  2012-02-16
  • Inventor:  Parthasarathy, Sampath
    • Compounds are provided that comprise dinitroso-derivatives of dihydrolipoic acid. Pharmaceutical compositions comprising the compounds and methods of using the compounds for treating various diseases and disorders, including angina, hypertension, diabetes, dyslipidemia, renal insufficiency, myocardial infarction, stroke, atherosclerosis, and the target organ damage that accompanies these various diseases and disorders, are further provided. The compounds are useful in improving vasodilation, ...
    ]]>     20120041025     <![CDATA[SUBSTITUTED BENZOFUSED DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS]]> http://www.patentstorm.us/applications/20120041011/description.html
  • Application Number:  20120041011
  • Publication Date:  2012-02-16
  • Inventors:  GHARAT, Laxmikant Atmaram; JOSHI, Uday Mukund; KHAIRATKAR-JOSHI, Neelima; KADAM, Suresh Mahadev
    • The present invention relates to substituted benzofused derivatives, which can he used as vanilloid receptor ligands, method of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing ...
    ]]>     20120041011     <![CDATA[P38 KINASE INHIBITING AGENTS]]> http://www.patentstorm.us/applications/20120040999/description.html
  • Application Number:  20120040999
  • Publication Date:  2012-02-16
  • Inventors:  Yang, Ginger Xu-Qiang; Sahoo, Soumya P.; Koyama, Hiroo; Miller, Daniel J.
    • Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: Formula (I); are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and ...
    ]]>     20120040999     <![CDATA[3-BENZOFURANYL-INDOL-2-ONE DERIVATIVES SUBSTITUTED AT THE 3 POSITION, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF]]> http://www.patentstorm.us/applications/20120040996/description.html
  • Application Number:  20120040996
  • Publication Date:  2012-02-16
  • Inventors:  Baroni, Marco; Puleo, Letizia
    • The invention relates to 3-benzofuranyl-indol-2-one derivatives substituted at the 3 position and of the formula (I) where R1, R2, R3, R4, R5 and n are such as defined in claim 1, to a method for preparing same, and to the therapeutic use of said compounds.

    ]]> 20120040996 <![CDATA[DERIVATIVES OF 6-(6-NH-SUBSTITUTED-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLES AND BENZIMIDAZOLES, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS]]> http://www.patentstorm.us/applications/20120040987/description.html

  • Application Number:  20120040987
  • Publication Date:  2012-02-16
  • Inventors:  Ugolini, Antonio; Nemecek, Conception; Wentzler, Sylvie; Bacque, Eric
    • The invention relates to novel products of the formula (I) where: (II) is a single or double bond; Rb is a hydrogen or fluorine atom; Ra is a NH-Rc radical in which Rc is an optionally substituted heterocycloalkyl, aryl, heteroaryl or -alkylcycloalkyl radical; X is S, SO, or SO2; A is NH or S; W is H, alkyl, or COR with R being cycloalkyl; alkyl; alkoxy; O-phenyl; —O— (CH2)n-phenyl with n=1 to 4; or NR1R2 with R1 being H or alk and R2 is H, cycloalkyl or alkyl; or R1, R2 form a cycle ...
    ]]>     20120040987     <![CDATA[OMEGA CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS]]> http://www.patentstorm.us/applications/20120040986/description.html
  • Application Number:  20120040986
  • Publication Date:  2012-02-16
  • Inventors:  WOOD, Jill E.; RIEDL, Bernd; DUMAS, Jacques; KHIRE, Uday; LOWINGER, Timothy B.; SCOTT, William J.; SMITH, Roger A.; MONAHAN, Mary-Katherine; NATERO, Reina; RENICK, Joel; SIBLEY, Robert N.
    • This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such ...
    ]]>     20120040986     <![CDATA[TRIAZOLE AND IMIDAZOLE DERIVATIVES FOR USE AS TGR5 AGONISTS IN THE TREATMENT OF DIABETES AND OBESITY]]> http://www.patentstorm.us/applications/20120040985/description.html
  • Application Number:  20120040985
  • Publication Date:  2012-02-16
  • Inventors:  Flatt, Brenton T.; Morrissey, Michael; Boren, Brant Clayton; Gu, Xiao-Hui; Martin, Richard; Wang, Tie-Lin; Mohan, Raju; Bollu, Venkataiah; Julien, Jackaline Dalgard; Haq, Nadia; Hudson, Sarah; Pratt, Benjamin
    • The present invention comprises TGR5 agonists of structural formula I,

    wherein X, R1, R2, and R5 are defined herein, as well as N-oxides of them and pharmaceutically acceptable salts thereof. The invention further comprises composition comprising the compounds, N-oxides, and/or pharmaceutically acceptable salts thereof. The invention also comprises use of the compounds and compositions for treating ...
    ]]> 20120040985 <![CDATA[THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF]]> http://www.patentstorm.us/applications/20120040984/description.html

  • Application Number:  20120040984
  • Publication Date:  2012-02-16
  • Inventors:  Nicolai, Eric; Fett, Eykmar; Mougenot, Patrick; Namane, Claudie; Philippo, Christophe
    • The invention relates to compounds of the formula (I) either (i) in the state of a base or an acid addition salt, or (ii) in the state of an acid or a base addition salt, as well as to a method for preparing same and to the therapeutic applications thereof.

    ]]> 20120040984 <![CDATA[INHIBITORS OF HCV NS5A]]> http://www.patentstorm.us/applications/20120040977/description.html

  • Application Number:  20120040977
  • Publication Date:  2012-02-16
  • Inventors:  Li, Leping; Zhong, Min
    • Provided herein are compounds, pharmaceutical compositions and combination therapies for inhibition of hepatitis ...
    ]]>     20120040977     <![CDATA[MIF MODULATORS]]> http://www.patentstorm.us/applications/20120040974/description.html
  • Application Number:  20120040974
  • Publication Date:  2012-02-16
  • Inventors:  Jorgensen, William L.; Bucala, Richard J.
    • The invention provides novel heterocyclic compounds, pharmaceutical compositions and methods of treatment that modulate levels of MIF expression and treat disorders associated with high or low levels of MIF ...
    ]]>     20120040974     <![CDATA[FUSED RING INHIBITORS OF HEPATITIS C]]> http://www.patentstorm.us/applications/20120040962/description.html
  • Application Number:  20120040962
  • Publication Date:  2012-02-16
  • Inventors:  Li, Leping; Zhong, Min
    • Provided herein are compounds, pharmaceutical compositions and combination therapies for treatment of hepatitis ...
    ]]>     20120040962     <![CDATA[4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2]]> http://www.patentstorm.us/applications/20120040960/description.html
  • Application Number:  20120040960
  • Publication Date:  2012-02-16
  • Inventors:  Hou, Cuifen; Zhang, Xuqing; Hufnagel, Heather Rae; Sui, Zhihua; Johnson, Dana L.
    • The present invention comprises compounds of Formula (I):

    wherein: X, R1, R2, R3, and R4 are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a ...
    ]]> 20120040960 <![CDATA[INDOLE CARBOXAMIDES AS IKK2 INHIBITORS]]> http://www.patentstorm.us/applications/20120040958/description.html

  • Application Number:  20120040958
  • Publication Date:  2012-02-16
  • Inventors:  Fu, Wei; Jin, Qi; Li, Huijie; Busch-Petersen, Jakob; Neipp, Christopher E.; Boehm, Jeffrey Charles; Lin, Xichen; Lin, Guoliang; Kerns, Jeffrey K.
    • The invention is directed to novel indole carboxamide compounds. Specifically, the invention is directed to compounds according to formula (I):

    wherein R1, R2, R3, R4, and m are as defined herein.

    The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, such as rheumatoid arthritis, asthma, ...
    ]]> 20120040958 <![CDATA[AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY]]> http://www.patentstorm.us/applications/20120040948/description.html

  • Application Number:  20120040948
  • Publication Date:  2012-02-16
  • Inventors:  Lange, Udo; Ochse, Michael; Amberg, Wilhelm; Hutchins, Charles W.; POHLKI, Frauke; Behl, Berthold
    • The present invention relates to aminoindane derivatives of the formula (I)

    or a physiologically tolerated salt thereof.

    The invention relates to pharmaceutical compositions comprising such aminoindane derivatives, and the use of such aminoindane derivatives for therapeutic purposes. The aminoindane derivatives are GlyT1 ...
    ]]> 20120040948 <![CDATA[TETRALINE AND INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY]]> http://www.patentstorm.us/applications/20120040947/description.html

  • Application Number:  20120040947
  • Publication Date:  2012-02-16
  • Inventors:  Lange, Udo; Ochse, Michael; Amberg, Wilhelm; Pohlki, Frauke; Hutchins, Charles W.; Behl, Berthold
    • The present invention relates to tetraline and indane derivatives of the formula (I)

    or a physiologically tolerated salt thereof.

    The invention relates to pharmaceutical compositions comprising such tetraline and indane derivatives, and the use of such tetraline and indane derivatives for therapeutic purposes. The tetraline and indane derivatives are GlyT1 ...
    ]]> 20120040947 <![CDATA[COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS]]> http://www.patentstorm.us/applications/20120040937/description.html

  • Application Number:  20120040937
  • Publication Date:  2012-02-16
  • Inventors:  Borella, Christopher; Jiang, Jun; Koya, Keizo; Chen, Shoujun; Sun, Lijun
    • The invention relates to compounds of structural formula (I):

    or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as ...
    ]]> 20120040937 <![CDATA[CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF]]> http://www.patentstorm.us/applications/20120040932/description.html

  • Application Number:  20120040932
  • Publication Date:  2012-02-16
  • Inventors:  Boyer, Serge; Dudley, Michael N.; Griffith, David C.; Totrov, Maxim; Hirst, Gavin; Reddy, Raja; Hecker, Scott; Rodny, Olga
    • Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic ...
    ]]>     20120040932     <![CDATA[NOVEL HERBICIDES]]> http://www.patentstorm.us/applications/20120040826/description.html
  • Application Number:  20120040826
  • Publication Date:  2012-02-16
  • Inventors:  Mathews, Christopher John; Smith, Steve; Taylor, John Benjamin; Jeanmart, Stephane André Marie
    • Bicyclic dione compounds, and derivatives thereof, which are suitable for use as herbicides.

    ]]> 20120040826 <![CDATA[ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS]]> http://www.patentstorm.us/applications/20120040011/description.html

  • Application Number:  20120040011
  • Publication Date:  2012-02-16
  • Inventors:  Boons, Geert-Jan; Guo, Jun; Ning, Xinghai; Wolfert, Margaretha
    • 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a ...
    ]]>     20120040011     <![CDATA[Hepatitis C Virus Inhibitors]]> http://www.patentstorm.us/applications/20120039847/description.html
  • Application Number:  20120039847
  • Publication Date:  2012-02-16
  • Inventor:  Zhao, Shu-Hai
    • The present invention provides compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV ...
    ]]>     20120039847     <![CDATA[Novel Tricyclic Modulators of Cannabinoid Receptors]]> http://www.patentstorm.us/applications/20120039804/description.html
  • Application Number:  20120039804
  • Publication Date:  2012-02-16
  • Inventors:  Diaz, Philippe; Diaz, Fanny; Petrov, Ravil Rashitovich
    • The compounds of the invention are modulators of cannabinoid receptors CB1 or CB2. The compounds can be used for the prevention or treatment of, e.g., pain, cancer, skin diseases, weight-associated disorders, chemical addictions, psychiatric disorders, neurodegenerative disorders, bone diseases, and inflammatory diseases. The compounds of the invention can further be used to study these diseases and disorders, as well as cannabinoid receptor biology, by coupling the compounds to, e.g., imaging ...
    ]]>     20120039804     <![CDATA[Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same]]> http://www.patentstorm.us/applications/20120038264/description.html
  • Application Number:  20120038264
  • Publication Date:  2012-02-16
  • Inventors:  LIU, Hsiao Chan; Chen, Min Sheng; Lee, Chin Yi
    • The present invention relates to novel carbazole derivatives and an organic light-emitting diode device using the same. These carbazole derivatives can simultaneously or singly be used as a hole transporting layer, a host or guest of an emitting layer or an electron transporting layer of an organic light-emitting diode ...
    ]]>     20120038264     <![CDATA[CHRYSENE COMPOUNDS FOR LUMINESCENT APPLICATIONS]]> http://www.patentstorm.us/applications/20120037898/description.html
  • Application Number:  20120037898
  • Publication Date:  2012-02-16
  • Inventors:  Gao, Weiying; Wu, Weishi; Merlo, Jeffrey A.; Herron, Norman; Rostovtsev, Vsevolod
    • This invention relates to chrysene compounds that are useful in electroluminescent applications. It also relates to electronic devices in which the active layer includes such a chrysene ...
    ]]>     20120037898     <![CDATA[NOVEL CYCLOALKENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICES USING THE SAME]]> http://www.patentstorm.us/applications/20120037892/description.html
  • Application Number:  20120037892
  • Publication Date:  2012-02-16
  • Inventors:  Bae, Jae-Soon; Kim, Seong-So; Lee, Jae-Chol; Jang, Hye-Young; Kim, Jeung-Gon; Kim, Chang-Hwan
    • The present invention relates to a novel cycloalkene derivative, and an organic electronic device using the same. The cycloalkene derivative according to the exemplary embodiment of the present invention may act as a hole injection, a hole transport, an electron injection, an electron transport, or a light emitting material in an organic light emitting diode and an organic electronic device, and in particular, may be used alone as a light emitting host or a ...
    ]]>     20120037892     <![CDATA[PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME]]> http://www.patentstorm.us/applications/20120037890/description.html
  • Application Number:  20120037890
  • Publication Date:  2012-02-16
  • Inventors:  Ikeda, Kiyoshi; Sawano, Bunji; Sado, Takayasu; Okuda, Fumio; Ochi, Takahiko; Tanabe, Yoshimitsu
    • A pyrromethene-boron complex compound represented by the following formula (1);

    wherein Z1 and Z2 are independently a hydrogen atom, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkoxy group or a substituted or unsubstituted aryloxy group, at least one of Z1 and Z2 is an alkoxy group substituted with a fluorine atom or an aryloxy group substituted with a ...
    ]]> 20120037890 <![CDATA[PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF]]> http://www.patentstorm.us/applications/20120035374/description.html

  • Application Number:  20120035374
  • Publication Date:  2012-02-09
  • Inventors:  Panagiotidis, Thoedoros; Lithadioti, Alexandra; Koftis, Theoharis V.; Soni, Rohit Ravikant
    • The present invention relates to an improved process for the preparation of fluvastatin or pharmaceutical acceptable salts or derivatives thereof, in particular to a one-pot process for large scale production of Fluvastatin and salts thereof in high yield and high purity and pharmaceutical preparations containing said ...
    ]]>     20120035374     <![CDATA[PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES]]> http://www.patentstorm.us/applications/20120035373/description.html
  • Application Number:  20120035373
  • Publication Date:  2012-02-09
  • Inventors:  KAWAHARA, Shigeru; FUNAKOSHI, Nao
    • The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical ...
    ]]>     20120035373     <![CDATA[PROCESS FOR THE MANUFACTURE OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF]]> http://www.patentstorm.us/applications/20120035371/description.html
  • Application Number:  20120035371
  • Publication Date:  2012-02-09
  • Inventor:  SCHWEIZER, Steffen
    • The current invention describes novel chiral synthetic routes and intermediates for the manufacture of chiral anti-inflammatory agents of general formula VIII

    in which at least one of the groups X1, X2, X3 is selected from

    • fluoro, chloro, bromo, hydroxy, methoxy, ethoxy, trifluoromethyl, amino
    • ]]> 20120035371 <![CDATA[PROCESS FOR THE PREPARATION OF PYRIDO[2,1-a] ISOQUINOLINE DERIVATIVES]]> http://www.patentstorm.us/applications/20120035368/description.html
    • Application Number:  20120035368
    • Publication Date:  2012-02-09
    • Inventors:  Abrecht, Stefan; Adam, Jean-Michel; Fettes, Alec
    The present invention relates to a novel process for the preparation of pyrido[2,1-a]isoquinoline derivatives of the formula

    wherein R2, R3 and R4 are each independently selected from the group consisting of hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy and lower alkenyl, wherein lower alkyl, lower alkoxy and lower alkenyl may optionally be substituted by a group consisting of lower ...
    ]]> 20120035368 <![CDATA[SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST)]]> http://www.patentstorm.us/applications/20120035361/description.html

  • Application Number:  20120035361
  • Publication Date:  2012-02-09
  • Inventors:  Bunch, Lennart; Jensen, Anders Asbjørn
    • The invention is the discovery of the use of the class of compounds represented by Formula I, as selective inhibitors of excitatory amino acid transporter (EAAT) subtype 1 (EAAT1) and its rodent ortholog L-glutamate/L-aspartate transporter (GLAST) for the study of function and distribution of EAAT1/GLAST in the central nervous system and studies of the physiological and pathological functions of the EAAT1/GLAST subtype in native tissues, cultured neurons, and/or animal models for CNS ...
    ]]>     20120035361     <![CDATA[Volatile Imidazoles and Group 2 Imidazole Based Metal Precursors]]> http://www.patentstorm.us/applications/20120035351/description.html
  • Application Number:  20120035351
  • Publication Date:  2012-02-09
  • Inventors:  Kim, Moo-Sung; Norman, John Anthony Thomas; Perez, Melanie K.
    • Sterically hindered imidazole ligands are described, along with their synthesis, which are capable of coordinating to Group 2 metals, such as: calcium, magnesium, strontium, in an eta-5 coordination mode which permits the formation of monomeric or dimeric volatile complexes.

    A compound comprising one or more polysubstituted imidazolate anions coordinated to a metal selected from the group consisting of barium, strontium, magnesium, radium or calcium or mixtures ...
    ]]> 20120035351