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		    <title>PatentStorm ->  Applications -> Organic compounds -- part of the class 532-570 series</title>
		    <link>http://www.patentstorm.us/rss/class/applications/rss-540.xml</link>
		    <description>Recent patent applications filings in USPTO Class 540 Organic compounds -- part of the class 532-570 series.</description>
		    <pubDate>Thu, 9 Feb 2012 15:01:41</pubDate>
		    <managingEditor>patents@patentstorm.us</managingEditor>
		    <language>en</language><item>
			         <title><![CDATA[PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC]]></title>
			         <link>http://www.patentstorm.us/applications/20120035357/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035357</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Kanagaraj, Sureshkumar; Udayampalayam Palanisamy, Senthilkumar; Addanki, Maruthi Chandrasekhara Kishor; Dasari, Vinod Babu; John Peter, John Bosco; Lakshmi Narayanan, Karthikeyan</li></ul>The present invention relates to an improved process for the preparation of the carbapenem antibiotic of formula (I) or its salts, hydrates and esters. The present invention further provides novel crystalline form of compound of general formula (III), wherein R<sup>3 </sup>is p-nitrobenzyloxy carbonyl.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[Volatile Imidazoles and Group 2 Imidazole Based Metal Precursors]]></title>
			         <link>http://www.patentstorm.us/applications/20120035351/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035351</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Kim, Moo-Sung; Norman, John Anthony Thomas; Perez, Melanie K.</li></ul>Sterically hindered imidazole ligands are described, along with their synthesis, which are capable of coordinating to Group 2 metals, such as: calcium, magnesium, strontium, in an eta-5 coordination mode which permits the formation of monomeric or dimeric volatile complexes.</p>
<p id="p-0002" num="0000">A compound comprising one or more polysubstituted imidazolate anions coordinated to a metal selected from the group consisting of barium, strontium, magnesium, radium or calcium or mixtures ...<br />]]></description>		         
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			         <title><![CDATA[DERIVATIVE OF [(3-HYDROXY-4 PYRON-2-YL)-METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS]]></title>
			         <link>http://www.patentstorm.us/applications/20120035255/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035255</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Fanelli, Mirco; Fusi, Vieri</li></ul>The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[DEUTERIUM-ENRICHED IXABEPILONE]]></title>
			         <link>http://www.patentstorm.us/applications/20120035227/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035227</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventor:</strong> &nbsp;Czarnik, Anthony W.</li></ul>The present application describes deuterium-enriched ixabepilone, pharmaceutically acceptable salt forms thereof, and methods of treating using the ...<br />]]></description>		         
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			         <title><![CDATA[RIFAXIMIN COMPOSITIONS AND METHOD OF USE]]></title>
			         <link>http://www.patentstorm.us/applications/20120035202/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035202</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Cannata, Vincenzo; Campana, Manuela; Viscomi, Giuseppe Claudio; Braga, Dario; Rosini, Goffredo; Confortini, Donatella; Righi, Paolo</li></ul>Forms of rifaximin (INN) antibiotic, such as the poorly crystalline form named rifaximin γ are described, along with the production of medicinal preparations containing rifaximin for oral and topical ...<br />]]></description>		         
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			         <title><![CDATA[SUBSTITUTED ISOQUINOLINE DERIVATIVE]]></title>
			         <link>http://www.patentstorm.us/applications/20120035159/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035159</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Hidaka, Hiroyoshi; Takahashi, Kouichi; Inoue, Yoshihiro; Sumi, Kengo; Nakamura, Ryohei</li></ul>The present invention provides an isoquinoline-6-sulfonamide derivative that is useful as a novel pharmaceutical agent. The present invention provides an isoquinoline-6-sulfonamide derivative represented by Formula (1), a salt thereof, or a solvate of the derivative or the salt: wherein X and Y each independently represent a direct bond, NH, CH═CH, O, or S; R<sup>1 </sup>and R<sup>2 </sup>each independently represent a hydrogen atom, a halogen atom, a cyano group, an alkyl group, or the like; ...<br />]]></description>		         
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			         <title><![CDATA[Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions]]></title>
			         <link>http://www.patentstorm.us/applications/20120035158/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035158</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;LOTZ, Ralf R.H.; HIMMELSBACH, Frank; MARK, Michael; ECKHARDT, Matthias; LANGKOPF, Elke; MAIER, Roland</li></ul>The present invention relates to substituted xanthines of general formula</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">wherein R<sup>1 </sup>to R<sup>4 </sup>are defined as in claim <b>1</b>, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV ...<br />]]></description>		         
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			         <title><![CDATA[2-PYRIDONE DERIVATIVES AS NEUTROPHIL ELASTASE INHIBITORS AND THEIR USE]]></title>
			         <link>http://www.patentstorm.us/applications/20120035157/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035157</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Andersson, Marjana; Lönn, Hans; Hansen, Peter; Nikitidis, Antonios; Sjölin, Petter</li></ul>There are provided novel compounds of formula (I),</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>4</sup>, G<sup>1</sup>, G<sup>2</sup>, L, Y and n are as defined in the Specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of neutrophil ...<br />]]></description>		         
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			         <title><![CDATA[METHOD FOR TREATMENT OF DISEASES]]></title>
			         <link>http://www.patentstorm.us/applications/20120035147/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035147</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventor:</strong> &nbsp;Bar-Or, David</li></ul>The invention provides a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering a vascular-hyperpermeability-inhibiting amount of a danazol compound to the animal. The invention also provides a method of modulating the cytoskeleton of an endothelial cell in an animal. The method comprises administering an effective amount of a danazol compound to the ...<br />]]></description>		         
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			         <title><![CDATA[INHIBITORS OF STAT3 AND USES THEREOF]]></title>
			         <link>http://www.patentstorm.us/applications/20120035114/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035114</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;McMurray, John S.; Mandal, Pijus K.; Liao, Warren S.; Robertson, Fredika; Chen, Xiaomin; Rajaopal, Ramesh; Ren, Zhiyong</li></ul>Compounds which inhibit the activity of signal transducer and activator of transcription 3 (STAT3) are provided together with methods of making and using the same. The compounds are designed to bind to the SH2 domain of STAT3, preventing STAT3 from binding to receptors for interleukin-6 family cytokines, growth factors such as the platelet-derived growth factor, the epidermal growth factor, vascular endothelial growth factor, and other signaling molecules such as leptin. Blocking these ...<br />]]></description>		         
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			         <title><![CDATA[AZINONE-SUBSTITUTED AZABICYCLOALKANE-INDOLE AND AZABICYCLOALKANE-PYRROLO-PYRIDINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF]]></title>
			         <link>http://www.patentstorm.us/applications/20120035102/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120035102</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;GUZZO, Peter R.; SURMAN, Matthew David; ZHU, Lei</li></ul>Novel MCH-1 receptor antagonists are disclosed. These compounds are used in the treatment of various disorders, including obesity, anxiety, depression, non-alcoholic fatty liver disease, and psychiatric disorders. Methods of making these compounds are also described in the present ...<br />]]></description>		         
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			         <title><![CDATA[S1P Receptors Modulators]]></title>
			         <link>http://www.patentstorm.us/applications/20120034270/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120034270</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Grobelny, Damian W.; Gill, Gurmit S.</li></ul>The invention relates to novel compounds that have S1P receptor modulating activity and, preferably, apoptotic activity and/or anti proliferative activity against cancer cells and other cell types. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with in-appropriate S1P receptor modulating activity or expression, for example, cancer. A further aspect of the invention ...<br />]]></description>		         
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			         <title><![CDATA[CONDENSED PYRROLOPYRIDINE DERIVATIVE]]></title>
			         <link>http://www.patentstorm.us/applications/20120034250/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120034250</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Inoue, Takayuki; Nakajima, Yutaka; Yamagishi, Hiroaki; Maeda, Jun; Inami, Masamichi; Shirakami, Shohei; Tominaga, Hiroaki; Hondo, Takeshi; Morio, Hiroki; Mizutani, Tsuyoshi; Ishioka, Hiroki</li></ul>[Problem]</p>
<p id="p-0002" num="0000">The present invention provides a condensed pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction.</p>
<p id="p-0003" num="0000">[Means for Solution]</p>
<p id="p-0004" num="0000">The present inventors have extensively ...<br />]]></description>		         
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			         <title><![CDATA[TREATMENT OF NEUROTROPHIC FACTOR MEDIATED DISORDERS]]></title>
			         <link>http://www.patentstorm.us/applications/20120034193/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120034193</li><li><strong>Publication Date:</strong> &nbsp;2012-02-09</li><li><strong>Inventors:</strong> &nbsp;Orsi, Antonia; Xia, Zongqin; Hu, Yaer; Rees, Daryl; Howson, Patrick</li></ul>An agent selected from A/B-cis furostane, furostene, spirostane and spirostene steroidal sapogenins and ester, ether, ketone and glycosylated forms thereof is used to induce self-regulated homeostasis of neurotrophic factors (NFs), for example BDNF and/or GDNF, NFs with limited and manageable side effects in a subject, by modulating NFs in a non-toxic manner under homeostatic control. An effective amount of at least one such agent is administered to the subject, particularly in the treatment or ...<br />]]></description>		         
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			         <title><![CDATA[COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF]]></title>
			         <link>http://www.patentstorm.us/applications/20120029190/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029190</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Spear, Kerry L.; Hardy, Larry Wendell; Burdi, Douglas</li></ul>Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuro-muscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations ...<br />]]></description>		         
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			         <title><![CDATA[PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120029189/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029189</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Pippel, Daniel J.; Broggini, Diego; Lellek, Vit; Mani, Neelakandha S.; Lochner, Susanne; Maurer, Adrian; Young, Lana K.</li></ul>The present invention is directed to novel processes for the preparation of histamine H3 receptor modulators, in the treatment of for example, cognitive disorders, sleep disorders and/or psychiatric disorders.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[Substituted Aniline Derivatives]]></title>
			         <link>http://www.patentstorm.us/applications/20120029188/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029188</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Carr, Andrew David; Neuss, Judi Charlotte; Orchard, Michael Glen; Porter, David William</li></ul>The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal ...<br />]]></description>		         
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			         <title><![CDATA[HALOALKYLSULFONANILIDE DERIVATIVE]]></title>
			         <link>http://www.patentstorm.us/applications/20120029187/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029187</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Yano, Tetsuhiko; Kai, Masanori; Furuhashi, Takamasa; Masuzawa, Yoshihide; Saito, Fumiyo; Nakaya, Yoshihiko</li></ul>Novel herbicides are provided.</p>
<p id="p-0002" num="0000">A haloalkylsulfonanilide derivative represented by the formula (1) or an agrochemically acceptable salt thereof:
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">
    <ul id="ul0002" list-style="none">
        <li id="ul0002-0001" num="0000">the formula (1):</li>
    </ul>
    </li>
</ul>
</p>
<p id="p-0003" num="0000">
</p>
<p id="p-0004" num="0000">wherein Z is —C(R<sub>9</sub>)(R<sub>10</sub>)— or ...<br />]]></description>		         
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			         <title><![CDATA[AZA-DIBENZOCYCLOOCTYNES AND METHODS OF MAKING AND USING SAME]]></title>
			         <link>http://www.patentstorm.us/applications/20120029186/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029186</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;POPIK, VLADIMIR V.; Kuzmin, Alexander; Polukhtine, Andrei</li></ul>Convenient methods of preparing aza-dibenzocyclooctynes are disclosed herein. Aza-dibenzocyclooctynes attached to a surface are also disclosed herein. Aza-dibenzocyclooctynes can be reacted with azides to form heterocyclic compounds. Such reactions can be useful in a wide variety of applications including, for example, labeling ...<br />]]></description>		         
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			         <title><![CDATA[NOVEL INTERMEDIATES IN THE PREPARATION OF 1,4-DIPHENYL AZETIDINONE]]></title>
			         <link>http://www.patentstorm.us/applications/20120029185/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029185</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Singh, Girij Pal; Srivastava, Dhananjai; Shakya, Rajiv Kumar; Chaudhari, Namrata Anil; Ansari, Inamus Saqlain</li></ul>The process of the present invention relates to a method for the synthesis of a 1,4-diphenylazetidinone of formula (VIII) by using novel oxime intermediates.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[HETEROCYCLE-AMINO ACID DERIVATIVES FOR TARGETING CANCER TISSUE AND RADIOACTIVE OR NON-RADIOACTIVE LABELED COMPOUNDS THEREOF]]></title>
			         <link>http://www.patentstorm.us/applications/20120029177/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029177</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Lee, Myung Chul; Jeong, Jae Min; Lee, Dong Soo; Chung, June Key; Shetty, Dinesh</li></ul>The present invention relates to novel amino acid derivatives containing heterocyclic chelating residues thereof; radioactive or nonradioactive metal complexes thereof; methods for preparation thereof; and apyrogenic and sterile preparative kits of the composition for targeting cancer cells.</p>
<p id="p-0002" num="0000">The compounds of the present invention can easily be taken up to cancer cells as they contain amino acid residues thereof; radioactive or nonradioactive metals can be labeled ...<br />]]></description>		         
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			         <title><![CDATA[AUTO MAGNETIC METAL SALEN COMPLEX COMPOUND]]></title>
			         <link>http://www.patentstorm.us/applications/20120029167/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120029167</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Eguchi, Haruki; ISHIKAWA, Yoshihiro</li></ul>A drug using the magnetic properties of a metal salen complex as represented by the following general formula in order to magnetize the intended drug by chemically binding the drug to a metal salen complex so that the drug can be delivered to the target diseased site. The drug can be delivered to the diseased site using the magnetic properties of the drug per se without using a carrier made of a magnetic substance as in the conventional methods.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[SUBSTITUTED BICYCLIC HCV INHIBITORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028978/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028978</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Li, Leping; Zhong, Min</li></ul>Provided herein are compounds, pharmaceutical compositions and combination therapies for treatment of hepatitis ...<br />]]></description>		         
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			         <title><![CDATA[NOVEL DIBENZOFURANYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL USE]]></title>
			         <link>http://www.patentstorm.us/applications/20120028968/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028968</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Nielsen, Elsebet Østergaard; Dyhring, Tino; Peters, Dan; Christensen, Jeppe Kejser; Timmermann, Daniel B.</li></ul>This invention relates to novel dibenzofuranyl-oxadiazolyl-diazabicyclononane derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic ...<br />]]></description>		         
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			         <title><![CDATA[NOVEL DIAZA-BICYCLONONYL-PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE]]></title>
			         <link>http://www.patentstorm.us/applications/20120028967/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028967</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Nielsen, Elsebet Østergaard; Dyhring, Tino; Peters, Dan; Christensen, Jeppe Kejser; Timmermann, Daniel B.</li></ul>This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidine derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of ...<br />]]></description>		         
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			         <title><![CDATA[PROTEIN KINASE INHIBITORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028966/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028966</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Charrier, Jean-Damien; Durrant, Steve</li></ul>In one aspect, the invention provides compounds of Formula I</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">or pharmaceutically acceptable salts thereof. In another aspect, the invention provides methods for treatment of diseases or disorders mediated by a protein kinase, comprising administering a therapeutically effective amount of a compound of this ...<br />]]></description>		         
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			         <title><![CDATA[COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028965/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028965</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Mortimore, Michael; Brenchley, Guy; Knegtel, Ronald; Durrant, Steven; Charrier, Jean-Damien</li></ul>The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the ...<br />]]></description>		         
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			         <title><![CDATA[NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME]]></title>
			         <link>http://www.patentstorm.us/applications/20120028963/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028963</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Lee, Sung Sook; Lee, Kyung Joo; Lee, Chang Sik; Yang, Hyun Mo; Kim, Do Hoon; Choi, Dae Kyu; Choi, Ho Jin; Kim, Dal Hyun; Hwang, In Chang; Kim, Mi Jeong; Han, Byeong Hoon</li></ul>The present invention relates to hydroxamate derivatives, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof, the use thereof for preparing pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the compositions, and a method for preparing the hydroxamate ...<br />]]></description>		         
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			         <title><![CDATA[FUSED HETEROCYCLIC RING COMPOUND]]></title>
			         <link>http://www.patentstorm.us/applications/20120028962/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028962</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Imoto, Hiroshi; Kamaura, Masahiro; Rikimaru, Kentaro</li></ul>A compound represented by the following formula or a salt thereof, which has an GPR119 agonist action, is useful for the prophylaxis or treatment of diabetes, obesity and the like, and shows superior efficacy:</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">wherein
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">P: substituted 6-membered aromatic ring,</li>
    <li id="ul0001-0002" num="0000">Q: (substituted) 6-membered aromatic ring,</li>
    <li ...<br />]]></description>		         
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			         <title><![CDATA[6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist]]></title>
			         <link>http://www.patentstorm.us/applications/20120028961/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028961</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Galka, Christopher Stanley; Williams, Andrew Caerwyn; Boyd, Steven Armen; Briner, Karin; Martinez-Grau, Maria Angeles; Cohen, Michael Philip; Rothhaar, Roger Ryan; Hellman, Sarah Lynne; Reinhard, Matthew Robert; Singh, Ajay; ALLEN, JOHN GORDON; Rodriguez, Michael John; Tidwell, Michael Wade; Victor, Frantz; Zhang, Deyi; Conway, Richard Gerard; Deo, Arundhati S.; Lee, Wai-Man; Siedem, Christopher Stephen; MAZANETZ, Michael Philip</li></ul>The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT<sub>2C </sub>receptor agonists for the treatment of 5-HT<sub>2C </sub>associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">where:
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">
    <ul id="ul0002" list-style="none">
        <li id="ul0002-0001" ...<br />]]></description>		         
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			         <title><![CDATA[DIHYDROOROTATE DEHYDROGENASE INHIBITORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028959/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028959</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Arlt, Michael; Schwarz, Matthias; Subramanya, Hosahalli; Thunuguntla, Siva Sanjeeva Rao; Kunnam, Satish Reddy; Sanivaru Vijay, Sekhar Reddy; Bingi, Chakrapani; Kusanur, Raviraj</li></ul>The invention relates to compounds of formula (I) wherein R<sup>1</sup>, R<sup>2</sup>, X<sup>1</sup>, X<sup>2</sup>, Y, R<sup>a</sup>, R<sup>b</sup>, Q have the meanings given in claim <b>1</b>. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis and also in the treatment of cancer disorders.</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[5-ALKYNYL-PYRIMIDINES]]></title>
			         <link>http://www.patentstorm.us/applications/20120028958/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028958</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;KESSLER, Dirk; SCHNEIDER, Siegfried; van der VEEN, Lars; WUNBERG, Tobias</li></ul>The present invention encompasses compounds of general formula (1)</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">wherein</p>
<p id="p-0004" num="0000">R<sup>1 </sup>to R<sup>4 </sup>R<sup>3 </sup>are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned ...<br />]]></description>		         
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			         <title><![CDATA[Inhibitors Of The Influenza A Virus M2 Proton Channel]]></title>
			         <link>http://www.patentstorm.us/applications/20120028957/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028957</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Wang, Jun; DeGrado, William F.</li></ul>Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 ...<br />]]></description>		         
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			         <title><![CDATA[5-ALKYNYL-PYRIMIDINES]]></title>
			         <link>http://www.patentstorm.us/applications/20120028952/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028952</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;KESSLER, Dirk; SCHNEIDER, Siegfried; van der VEEN, Lars; WUNBERG, Tobias</li></ul>The present invention encompasses compounds of general formula (1)</p>
<p id="p-0002" num="0000">
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">
    <ul id="ul0002" list-style="none">
        <li id="ul0002-0001" num="0000">wherein</li>
        <li id="ul0002-0002" num="0000">R<sup>1 </sup>to R<sup>3 </sup>are defined as in claim <b>1</b>, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for ...<br />]]></description>		         
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			         <title><![CDATA[5-Beta, 14-Beta-Androstane Derivatives Useful For The Treatment Of Proteinuria, Glomerulosclerosis And Renal Failure]]></title>
			         <link>http://www.patentstorm.us/applications/20120028945/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028945</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Bianchi, Giuseppe; Ferrari, Patrizia; Ferrandi, Mara</li></ul>Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of proteinuria, glomerulosclerosis or renal ...<br />]]></description>		         
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			         <title><![CDATA[HETEROCYCLIC M-GLU5 ANTAGONISTS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028931/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028931</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Graziani, Davide; Guarneri, Luciano; Leonardi, Amedeo; Riva, Carlo; Motta, Gianni; Marinoni, Fabio; Bettinelli, Ilaria</li></ul>Compounds I</p>
<p id="p-0002" num="0000">
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">(R<sub>1 </sub>is an optionally substituted C<sub>1</sub>-C<sub>13 </sub>heteromonocyclic, heterobicyclic or heterotricyclic group containing from 1 to 5 heteroatoms selected from N, O and S;</li>
    <li id="ul0001-0002" num="0000">R<sub>2 </sub>is H, an optionally substituted monocyclic aromatic group, or a C<sub>1</sub>-C<sub>5 </sub>heteroaromatic group containing from 1 to 4 ...<br />]]></description>		         
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			         <title><![CDATA[Phosphate Management with Small Molecules]]></title>
			         <link>http://www.patentstorm.us/applications/20120028926/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028926</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Saha, Uttam; Petkovich, P. Martin; Helvig, Christian F.</li></ul>This invention relates to methods and small molecules having a phosphate group that can be used to inhibit phosphate transport and to treat or prevent diseases that are related to disorders in the maintenance of normal serum phosphate ...<br />]]></description>		         
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			         <title><![CDATA[DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028920/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028920</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Kuroda, Takeshi; Fukushima, Tae; Ito, Nobuaki; Kondo, Kazumi; Kuroda, Hideaki; Matsubara, Jun; YAMASHITA, Hiroshi; Oshima, Kunio; Takahashi, Haruka; Tanaka, Tatsuyoshi; Shimizu, Satoshi; Sakurai, Yohji; Itotani, Motohiro; Miyamura, Shin; Taira, Shinichi</li></ul>A heterocyclic compound or a salt thereof represented by the formula (1):</p>
<p id="p-0002" num="0000">
<ul id="ul0001" list-style="none">
    <li id="ul0001-0001" num="0000">
    <ul id="ul0002" list-style="none">
        <li id="ul0002-0001" num="0000">where R<sup>2 </sup>represents a hydrogen atom or a lower alkyl group;</li>
        <li id="ul0002-0002" num="0000">A represents a lower alkylene group or lower alkenylene group; and</li>
        <li id="ul0002-0003" num="0000">R<sup>1 ...<br />]]></description>		         
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			         <title><![CDATA[PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028919/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028919</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Josef, Kurt A.; Dorsey, Bruce D.; Breslin, Henry J.; Dunn, Derek D.; Milkiewicz, Karen L.; Chatterjee, Sankar; Theroff, Jay P.; Weinberg, Linda; Hostetler, Greg A.; Tripathy, Rabindranath; Zificsak, Craig A.; Sundar, Babu G.; Diebold, James L.; Gingrich, Diane E.; Underiner, Theodore L.; Hudkins, Robert L.; Hunter, Rachael; Lisko, Joseph; Mesaros, Eugen F.; Ott, Gregory R.; Thieu, Tho; Wells, Gregory J.</li></ul>The present invention provides a compound of formula I</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">or a salt form thereof, wherein Q<sup>1</sup>, Q<sup>2</sup>, Q<sup>3</sup>, and Q<sup>4 </sup>are as defined herein. The compound of formula I has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative ...<br />]]></description>		         
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			         <title><![CDATA[Methods of Manufacturing Crystalline Forms of Rapamycin Analogs]]></title>
			         <link>http://www.patentstorm.us/applications/20120028908/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028908</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Leanna, Robert; Rasmussen, Michael; Chen, Shuang; Zhang, Geoff; Bartelt, Larry; Dhaon, Madhup; Henry, Rodger; Borchardt, Thomas; VISWANATH, Shekhar</li></ul>A process for preparing a crystalline rapamycin analog includes: combining the rapamycin analog with an organic medium to form a mixture; incubating the mixture until the rapamycin analog crystallizes; and recovering the crystalline rapamycin analog. The organic medium can be a solvent, and the process can include causing the rapamycin analog to dissolve into the solvent, and incubating the solvent until the rapamycin analog crystallizes. The following can also be performed: forming a slurry of ...<br />]]></description>		         
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			         <title><![CDATA[METHODS FOR IDENTIFICATION OF TUMOR PHENOTYPE AND TREATMENT]]></title>
			         <link>http://www.patentstorm.us/applications/20120028907/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028907</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventor:</strong> &nbsp;Shackney, Stanley E.</li></ul>The disclosure relates to methods for identifying a tumor as an E2F-responsive gene over-expressing (ERGO) tumor, methods of determining the likelihood that an ERGO tumor patient will survive to a future date, methods of treating an ERGO tumor in a patient, and methods of selecting patients diagnosed as ERGO tumor prostate cancer patients for aggressive clinical treatment. The methods of the disclosure are applicable to ERGO tumors present in different human organs and tissues such as breast, ...<br />]]></description>		         
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			         <title><![CDATA[ENZYMATIC PROCESS FOR THE PREPARATION OF (S)-5-(4-FLUORO-PHENYL)-5-HYDROXY- 1MORPHOLIN-4-YL-PENTAN-1-ONE, AN INTERMEDIATE OF EZETIMIBE AND FURTHER CONVERSION TO EZETIMIBE]]></title>
			         <link>http://www.patentstorm.us/applications/20120028316/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028316</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Husain, Mofazzal; Srikanth, G.S.C; Thorpunuri, Swapna; Debashish, Datta</li></ul>The present invention provides an enzymatic process for the preparation of (S)-5-(4-Fluoro-phenyl)-5-hydroxy-1morpholin-4-yl-pentan-1-one by the reduction of 1-(4-Fluoro-phenyl)-5-morpholin-4-yl-pentane-1,5-dione by using a suitable enzyme or by the resolution of (R,S)-5-(4-Fluoro-phenyl)-5-hydroxy-1morpholin-4-yl-pentan-1-one by using an enzyme. The present invention also provides process for the preparation of Ezetimibe comprising the steps of a) protecting the compound ...<br />]]></description>		         
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			         <title><![CDATA[CHARGED-BALANCED IMAGING AGENTS]]></title>
			         <link>http://www.patentstorm.us/applications/20120028291/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120028291</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Frangioni, John V.; Henary, Maged M.</li></ul>The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ...<br />]]></description>		         
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			         <title><![CDATA[PHARMACEUTICAL COMPOSITION CONTAINING A "LIMUS" FAMILY IMMUNOSUPPRESSIVE MACROLIDE]]></title>
			         <link>http://www.patentstorm.us/applications/20120027852/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120027852</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Deschamps, Frantz; Herry, Catherine; Jung, Jennifer; Leboeuf, Fabrice</li></ul>A pharmaceutical formulation includes a Limus family immunosuppressive macrolide on a pharmaceutically acceptable excipient, which may be compounded as suitable for oral ...<br />]]></description>		         
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			         <title><![CDATA[NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS]]></title>
			         <link>http://www.patentstorm.us/applications/20120027796/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120027796</li><li><strong>Publication Date:</strong> &nbsp;2012-02-02</li><li><strong>Inventors:</strong> &nbsp;Butler, David; Narayanannair, Jayaprakash K.; Jayaraman, Muthusamy; Rajeev, Kallanthottathil G.; Manoharan, Muthiah; Eltepu, Laxmab</li></ul>The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structures: (Formula (I) or (XXXV)).</p>
<p id="p-0002" ...<br />]]></description>		         
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			         <title><![CDATA[PROCESS FOR PREPARING CEPHALOTAXINE ESTERS]]></title>
			         <link>http://www.patentstorm.us/applications/20120022250/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120022250</li><li><strong>Publication Date:</strong> &nbsp;2012-01-26</li><li><strong>Inventors:</strong> &nbsp;Robin, Jean-Pierre; Radosevic, Nina; Blanchard, Julie</li></ul>A process for preparing cephalotaxine esters corresponding to the following general formula I which comprises the cephalotaxine backbone: C(R<sup>1</sup>)(R<sup>2</sup>)(XH)COO[CTX] wherein CTX represents the cephalotaxine backbone, being optionally substituted and/or dehydrogenated, in which formula I, X is a heteroatom, preferably an oxygen, a sulfur or a nitrogen, R<sup>1 </sup>and R<sup>2</sup>, taken separately, may be alkyl, cycloalkyl, heteroalkyl, aryl, heteroaryl, heterocycloalkyl or ...<br />]]></description>		         
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			         <title><![CDATA[AMINODIHYDROTHIAZINE DERIVATIVES]]></title>
			         <link>http://www.patentstorm.us/applications/20120022249/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120022249</li><li><strong>Publication Date:</strong> &nbsp;2012-01-26</li><li><strong>Inventors:</strong> &nbsp;KOBAYASHI, Naotake; UEDA, Kazuo; ITOH, Naohiro; SUZUKI, Shinji; SAKAGUCHI, Gaku; KATO, Akira; YUKIMASA, Akira; HORI, Akihiro; KORIYAMA, Yuji; HARAGUCHI, Hidekazu; YASUI, Ken; KANDA, Yasuhiko</li></ul>A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I):</p>
<p id="p-0002" num="0000">
</p>
<p id="p-0003" num="0000">wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group;
<br/>
E is lower alkylene;
<br/>
X is S, O, or NR<sup>1</sup>;
<br/>
R<sup>1 </sup>is a hydrogen atom or lower alkyl;
<br/>
R<sup>2a</sup>, R<sup>2b</sup>, R<sup>3a</sup>, R<sup>3b</sup>, R<sup>4a </sup>and R<sup>4b ...<br />]]></description>		         
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			         <title><![CDATA[B-LACTAM COMPOUNDS]]></title>
			         <link>http://www.patentstorm.us/applications/20120022248/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120022248</li><li><strong>Publication Date:</strong> &nbsp;2012-01-26</li><li><strong>Inventors:</strong> &nbsp;Vaske, Yvette S.; Mahoney, Maximillian E.; Konopelski, Joseph P.</li></ul>Novel methods for the production of enantiomerically pure (EP) β-lactams by decomposition of ...<br />]]></description>		         
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			         <title><![CDATA[NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES]]></title>
			         <link>http://www.patentstorm.us/applications/20120022049/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120022049</li><li><strong>Publication Date:</strong> &nbsp;2012-01-26</li><li><strong>Inventors:</strong> &nbsp;CORMIER, YVON; ISRAEL-ASSAYAG, EVELYNE; BLANCHET, MARIE-RENEE; GAUDREAULT, RENE C.; LABRIE, PHILIPPE</li></ul>Nicotine receptor agonists or analogs or derivatives thereof for treating inflammatory pulmonary diseases, and pharmaceutical compositions including nicotine receptor agonists or analogs or derivatives thereof. Compounds of formula wherein R1, R2, Xa and Ya are as defined herein are also ...<br />]]></description>		         
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			         <title><![CDATA[PROCESS FOR THE PURIFICATION OF ESLICARBAZEPINE ACETATE]]></title>
			         <link>http://www.patentstorm.us/applications/20120022047/description.html</link>
			         <description><![CDATA[<ul><li><strong>Application Number:</strong> &nbsp;20120022047</li><li><strong>Publication Date:</strong> &nbsp;2012-01-26</li><li><strong>Inventors:</strong> &nbsp;Koilpillai, Joseph Prabahar; Kulkarni, Pravin Bhalchandra; Sawant, Sachin Bapurao; Limbekar, Nagesh Devidasrao</li></ul>The present invention relates to the purification and particle size of eslicarbazepine acetate. The present invention also relates to the physical characteristics of solid state eslicarbazepine acetate, and pharmaceutical compositions containing the ...<br />]]></description>		         
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