Cell-free assay product and method of use thereof for measuring activity of frizzled receptors

Patent 8119354 Issued on February 21, 2012. Estimated Expiration Date:

October 9, 2028. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

WNT signalling in reproductive organs Patent #: 6485972
Issued on: 11/26/2002
Inventor: McMahon, et al.

Inventor

Katanaev, Vladimir

Assignee

Universitaet Konstanz

Application

No. 12682282 filed on 10/09/2008

US Classes:

435/7.1Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay

Examiners

Primary: Landsman, Robert

Attorney, Agent or Firm

Pabst Patent Group LLP

Foreign Patent References

2005105850 WO 11/01/2005

International Classes

G01N 33/53
C12P 1/00
C12P 21/06
C12N 1/20
C12N 15/00
C12N 15/74
C07K 1/00
C07K 14/00
C07K 17/00

Abstract

The present invention relates to cell free assays for measuring receptor activity, especially for measuring a constitutive or a non-constitutive activity of frizzled re-ceptors and uses thereof. The present invention further concerns a method for measuring a constitutive or non-constitutive activity of a frizzled receptor and a method for obtaining an active frizzled receptor ligand.

Other References

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