Process for preparing ethyl (S)-2-ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of Repaglinide
Patent 8101769 Issued on January 24, 2012. Estimated Expiration Date: 
February 14, 2028. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 14, 2028. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPhenylacetic acid benzylamides Process for the preparation of repaglinide Patent #: 7148355 InventorsAssigneeApplicationNo. 12031184 filed on 02/14/2008US Classes:546/234Plural carbocyclic rings containingExaminersPrimary: Chang, CeliaAttorney, Agent or FirmForeign Patent References
International ClassC07D 211/22AbstractDescribed herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield.Other References
Field of SearchPlural carbocyclic rings containing |
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