ApplicationNo. 11226478 filed on 09/14/2005
US Classes:119/655Having means passing through the animal skin; e.g., ear tag
ExaminersPrimary: Swiatek, Rob
Assistant: Xavier, Valentina
Attorney, Agent or Firm
Foreign Patent References
International ClassA01K 13/00
DescriptionFIELD OF THE INVENTION
The present invention relates to fluid delivery and more particularly to a dispenser for delivering fluid over extended periods of time.
There are various methods used to control pests on large domestic animals such as livestock. Commonly employed methods include sprays and dusts, back rubbers and dust bags, and ear tags or tapes.
Sprays, dusts, and pour-on applications of pesticide involve manually applying pesticide to the animal's back. Although this method can be effective, it requires additional herding and handling and is generally not practical for large ranchesor for free-range cattle.
Back rubbers and dust bags are devices that are impregnated or filled with pesticide and suspended in a pasture in proximity to a salt lick, water supply or place the animals frequent. The animals make contact with these devices in the normalcourse of their routine. The dust bag or back rubber may also be located in a gateway which leads to a salt lick or water supply and which forces the animal to contact the device. Again, this method of insecticide application can be effective, but maynot be practical for certain situations such as large ranches or free-range cattle.
Ear tags are widely used and are generally made of a molded polymer matrix impregnated (i.e., saturated or immersed) with a substance such as a pesticide or parasiticide. These ear tags or tapes are attached to animals by piercing the ear witha sharp post and corresponding locking receptacle or with adhesive. The pesticide slowly leaches from the carrier material and is deposited onto the animal. The animal then spreads the material by moving its head from side to side and by rubbingalongside other animals.
The delivery of substance from these known ear tags is problematic. Among other delivery problems, the tags release the substance after packaging such that it crystallizes on the surface of the tag itself, thereby exposing the user to a highconcentration of the pesticide. Another significant problem is that the output of the tags is not constant. Initially, they supply excessive doses of the substance, but over time, their output falls below an effective or lethal level, where it remains. The tags then supply doses that are less than lethal for weeks or perhaps months before their nominal expiration date. Unfortunately, exposing parasites to a sub-lethal dose causes future generations of these pests to develop a resistance or immunity tothe substance. In turn, for a given area in which the tags are used, the type of tags used must be frequently changed so that the pests are exposed to a new substance to which they have not developed a resistance. This can create excess inventory oftags that are no longer effective, and can undesirably result in tags that have only been worn by the animals a short time before having to be replaced. The labor and costs associated with "re-tagging" animals mid-season can be quite large.
Moreover, the types of substances which can be used to saturate known ear tags is generally limited due to solubility and/or compatibility between the saturating substance and the polymer matrix. For example, compounds like ivermectin andspinosad have relatively high molecular weights and poor solubility in polymers such as polyethylene. These compounds are essentially incompatible with conventional ear tags.
Another problem with known ear tags is the inherent limit in the amount of liquid pesticide that can be saturated into a given size polymer matrix. It is not practical to produce a device large enough to contain sufficient insecticide to killpests for an entire season. The size of the device would be such that it interferes with the animal's normal routine and would likely cause discomfort or injury to the animal, such as eye irritation, drooping ears, tears in the ear at the location ofattachment, etc.
It would be desirable to have an application method and dispenser that is capable of dosing a repeatable, prolonged, and lethal application of pesticide to an animal with no gradual decline, but rather, a sudden and complete cessation ofexposure, and does not require further herding, handling or contact with the animal.
SUMMARY OF THE INVENTION
The present invention provides a dispenser that delivers a small but consistent and sustained dose of fluid over an extended period of time.
In one form thereof, the present invention provides a dispenser. The dispenser has a shell having an opening. A reservoir is disposed in the shell and is saturated with a liquid substance. A wick is in fluid communication with the reservoir. The wick extends through the opening and has a greater capillary attraction than the reservoir, whereby during use of the dispenser the wick draws pesticide from the reservoir and deposits the liquid substance on an animal upon contact.
In preferred forms of the dispenser, various methods may be used to provide the wick with a greater capillary attraction or wicking ability than the reservoir. For example, the wick may be made of a material having a greater density than thematerial from which the reservoir is formed. Also, depending upon the hydrophilicity of the substance being dispensed, a wick that is more hydrophilic than the reservoir may result in a greater capillary attraction for the wick. A wick having a smallerpore size than the reservoir may also result in the wick having a greater capillary attraction than the reservoir. In certain embodiments, the wick and the reservoir are comprised of the same material and the shell comprises a sleeve that exerts acompressive force on the wick to reduce its pore size and thus increase its capillary attraction.
In certain exemplary embodiments, the wick either protrudes from the opening or is substantially flush with the opening. More preferably, the shell comprises a sleeve which defines the opening, and the wick is disposed in the sleeve. A skirtextends from the shell, the skirt at least partially surrounding the sleeve.
In another form thereof, the present invention provides a novel method of dispensing a substance onto an animal. In this method, a pesticide dispenser is provided. The dispenser has a shell and a reservoir disposed in the shell. The reservoircontains or is saturated with a liquid substance such as a pesticide, and a wick is in fluid communication with the reservoir. The wick extends into the opening. In the inventive method, the dispenser is attached to the animal such that the wick isfree to contact the animal as the animal moves. The animal is permitted to go about its normal activities, during which the liquid substance is gradually dispensed from the dispenser and onto the animal by capillary action.
In a preferred form thereof, the wick has a greater capillary attraction than the reservoir and the wick continues to draw the substance from the reservoir and dispense it until the dispenser is essentially empty. More preferably, the liquidsubstance is a pesticide and the dispenser may dispense the pesticide for at least 120, and more preferably, at least 180 days when attached to an animal that goes about normal activities such as grazing.
One advantage of the present invention is that the dose of substance being dispensed remains substantially constant as the supply is being consumed. That is, the dose being dispensed does not drop off appreciably until the dispenser is almostempty. The amount of the dose dispensed with dispensers embodying the present invention is substantially independent of the volume of liquid contained in the dispenser. This addresses the problems with known polymer tags that initially produce anextremely high dose which soon drops off to a sub-lethal dose that quickly allows pests to develop a resistance or immunity to the substance being dispensed. Since dispensers in accordance with the present invention can produce a consistently lethaldose until substantially depleted, the chance of pests developing a tolerance to the substance is reduced, or at least takes much longer than with polymer saturated tags.
Another advantage of the present invention is that a small, lightweight dispenser may be filled with sufficient pesticide to last an entire season before being depleted. The costs and labor associated with mid season "re-tagging" are thusavoided with the present invention.
Yet another advantage of the present invention is that the dispensers can be handled and attached without contacting the substance contained therein. The only source of the pesticide (or whatever substance the dispenser may happen to contain)is the wick. However, in exemplary embodiments, the wick is either substantially flush with the opening or protrudes slightly from the opening. Touching the wick when, e.g., attaching the device to an animal's ear can easily be avoided.
Still another advantage of the present invention is that the shape of dispensers formed in accordance with preferred embodiments is ergonomic. That is, the animals generally appear able to tolerate wearing the dispensers for long periods oftime without noticeable irritation and without the dispensers getting ensnared by, e.g., fences, other animals, or otherwise interfering with the animals' normal routine.
BRIEF DESCRIPTION OF THE DRAWINGS
The above-mentioned and other advantages of the present invention, and the manner of obtaining them, will become more apparent and the invention itself will be better understood by reference to the following description of the embodiments of theinvention taken in conjunction with the accompanying drawings, wherein:
FIG. 1 is a perspective view of a dispenser in accordance with one embodiment of the present invention;
FIG. 1A is a perspective view of the dispenser shown in FIG. 1 with parts of the dispenser broken away to expose the interior of the dispenser;
FIG. 1B shows a modification of the dispenser shown in FIG. 1A in which the wick is substantially flush with the opening of the dispenser;
FIG. 2 is an exploded perspective view of the dispenser shown in FIG. 1;
FIG. 2A is a fragmentary perspective view of the dispenser of FIG. 1 with parts broken away to show a rib structure in accordance with an embodiment of the present invention;
FIG. 2B is a perspective view of the underside of a cap of the dispenser shown in FIG. 1;
FIG. 3 is a perspective view of the dispenser of FIG. 1 attached to an animal;
FIG. 4 is a perspective view of an alternate embodiment of a dispenser in accordance with the present invention with parts of the dispenser broken away to expose the interior thereof;
FIG. 5 is a side view of an alternate embodiment of a dispenser in accordance with the present invention;
FIG. 6 is a sectional view of an alternate embodiment of a dispenser in accordance with the present invention; and
FIG. 7 is a sectional view of another alternate embodiment of a dispenser in accordance with the present invention.
Corresponding reference characters indicate corresponding parts throughout the several views.
The embodiments of the present invention described below are not intended to be exhaustive or to limit the invention to the precise forms disclosed in the following detailed description. Rather, the embodiments are chosen and described so thatothers skilled in the art may appreciate and understand the principles and practices of the present invention.
Referring now to FIGS. 1 and 1A, dispenser 20 includes an outer shell 22 that defines a tip or sleeve 24 that terminates in an opening 26. Shell 22 in the illustrated embodiment is made of Formax 609, Acetal Copolymer from Chem PolymerCorporation, which is a fairly hard, lightweight material that is preferably formed by injection molding. One of skill in the art would readily recognize many suitable lightweight materials that could be used for shell 22, including various polymers,glass, hard rubber, wood, metal and the like. Disposed within shell 22 is reservoir 28 that is typically saturated with a pesticide that is held therein without substantial dripping by capillary action, as explained in more detail below. The materialchosen for reservoir 28 can be any of a wide variety of materials know in the art, such as fibrous bundles, sponge material, porous plastics and the like. Materials suitable for reservoir 28 generally contain the liquid substance therein by capillaryaction without allowing the liquid to drip from the material. For purposes of this specification, the term "pesticide" is meant to include substances that kill one or more types of numerous small invertebrate animals such as horn flies, face flies,beetles, gnats, spiders, centipedes, arthropods and the like. Furthermore, while the illustrated embodiment is described with reference to a pesticide, one of skill in the art would readily recognize that many liquid substances could be employed withdispensers embodying the present invention, including but not limited to medicaments, growth hormones, therapeutic agents, drugs, pheromones, pesticides, insecticides, repellants, scents, and the like. It is preferable that the liquid substance besubstantially non-volatile. Since the wick is typically exposed, a volatile liquid substance used with dispensers embodied by the present invention would tend to evaporate, undesirably causing the dispenser to "dry out." A series of ribs 29 and 31 holdsthe reservoir in place in the shell. As shown in FIG. 1A, a gap 30 exists between the reservoir 28 and the interior surface of shell 22 to facilitate venting during use.
Dispenser 20 includes a ring 32 that secures cap 34 to shell 22, as can be appreciated with reference to FIG. 2. Ring 32 has lips extending from its interior that interlock in a snap-fit engagement with lips 33 and 35 of cap 34 and shell 22,respectively. Integrally formed with cap 34 is attachment means or flexible grommet 36 that includes loop member 38 having a round hole 40 formed therein. The attachment mechanism is preferably formed of a flexible polymer such as a thermoplasticelastomer so that the dispenser can move as it hangs from the animal to which it is attached. One suitable polymer is Hytrel.RTM. 5526 from DuPont Engineering Polymers. Attachment member 42 includes a cylindrical post 44 extending from flange member46 and has a conical locking member 48 disposed at its terminal end. In use, member 48 is pushed through hole 40, as described in more detail below. While one attachment means has just been described, one of skill in the art would readily recognizenumerous other suitable attachment means, including tapes, adhesives, collars, harnesses, clamps, staples and many others.
A wick 50 is in fluid communication with reservoir 28 and extends through opening 26. Fluid communication is established by having the wick 50 pressed against or abutting reservoir 28, in those embodiments in which the reservoir and wick areformed separately. In the illustrated embodiment, wick 50 has a greater "capillary attraction" or "wicking ability" than does reservoir 28, which means that wick 50 will tend to draw fluid from reservoir 28 by means of capillary action, as explained ingreater detail below. A skirt 52 extends downwardly from shell 22 and protects wick 50, as explained below.
With reference to FIGS. 2 and 2A, it can be appreciated that ribs 31 are integrally formed with shell 22 and support the bottom of reservoir 28 and also define a cylindrical hollow space 54 through which wick 50 is received. Sleeve 24 includesnubs 56 that hold wick 50 in place in the sleeve and also hold it in place in an abutting relationship with reservoir 28 so that fluid transfer is facilitated. In certain embodiments, the nubs may hold the wick away from the sleeve and thereby provide avent space for air to enter the dispenser as fluid is dispensed. In other embodiments, the nubs may be eliminated. Sleeve 24 may be elongated as shown in FIGS. 1, 2 and 2A, or in other embodiments may merely comprise an opening in shell 22 throughwhich the wick is disposed. The sleeve may be employed to adjust the wicking properties of the wick, as explained in more detail below.
With reference to FIG. 2B, the bottom side of cap 34 includes circular ribs 29 extending therefrom. The ribs define aligned channels 60 for venting. As shown in FIG. 1, cap 34 includes a vent hole 62 formed therein which allows air to enter asfluid is dispensed from wick 52. The air enters through vent 62, and is able to reach gap 30 by means of channels 60. As shown, gap 30 continues along the length of reservoir 28 until it terminates at a void portion 64 that partially surrounds wick 50. Proper venting is necessary to prevent a vacuum effect that would counteract the capillary forces required for fluid payout.
With reference to FIGS. 1, 2 and 3, dispenser 20 is attached to the ear of animal 68, which in the illustrated embodiment is a cow. The dispenser is attached to the animal such that the wick is pointed downward and dispenser 20 is free to moveas the animal's ear is moved or "flicked" and can thus contact the animal as the animal goes about its normal activities. Dispenser 20 attaches to the animal's ear by means of attachment member 42 and flexible grommet 36. The animal's ear is piercedand post 44 is pushed through the hole produced by piercing and is then fed into hole 40. It has been found that post 44 of attachment member 42 is sized sufficiently long so as to avoid squeezing the animal's ear between flange member 46 and loopmember 40. Instead, the ear fits comfortably between flange member 46 and loop member 40. It has been found that this method of attachment allows dispenser 20 to be worn by a cow for several months without the cow's ear becoming irritated, even thoughdispenser 20 when full weighs about 30 grams.
When the wick touches the animal's fur or skin, the pesticide is dispensed by capillary action. While shown attached to the animal's ear, the dispenser 20 could be attached to the tail, hung around the neck or otherwise attached to the animal. The dispenser should be attached, however, such that the animal's normal movement causes the pesticide to be transferred to the animal's fur or skin by mechanical contact with the wick, much like a pen deposits ink on a page upon contact. Once theliquid pesticide is deposited onto the animal, it is further spread through the animal's normal movement and through contact with other animals. As the animal moves its head from side to side and rubs along other animals through social contact, it hasbeen found that the liquid pesticide is spread along the entire length of the animal.
As the animal's movement continues and pesticide is dispensed from wick 50, wick 50 in turn continues to draw pesticide from reservoir 28 because, as noted above, the wick has a greater capillary attraction than the reservoir. Advantageously,the wick continues to draw pesticide from the reservoir and dispenses the pesticide until the dispenser is essentially emptied of pesticide and provides a substantially constant level of output until the dispenser is almost empty. In other words, therate of dispensing is substantially independent of the amount of fluid contained in the reservoir until the reservoir is close to being empty. Thus, the problems with saturated polymer tags in which the pesticide quickly drops off to a sub-lethal doseare avoided. In conditions of normal use, the dispenser can be used for at least 30 days, preferably 60 days, more preferably at least 120 days, and most preferably at least 180 days, before the pesticide is depleted. This is longer than known polymertags that are saturated with pesticides. The amount of substance dispensed per contact can be adjusted by adjusting the extent to which the wick protrudes from the opening. In certain exemplary embodiments, the end of the wick 50' shown in FIG. 1Bterminates at a position that is substantially flush with the opening. In other embodiments, the end of the wick may be slightly recessed within the opening, but still provide sufficient contact with the fur of the animal to obtain an optimum dispenserate. If the wick protrudes only slightly or does not protrude from the opening, the possibility of it becoming caught on or making excess contact with the animal's fur is reduced.
As noted above, wick 50 must have a greater capillary attraction than the reservoir. It should be understood that for purposes of this application, "capillary attraction" means the tendency of a material to draw liquid therein. The higher the"capillary attraction," the greater this tendency. Those of skill in the art also refer to this tendency as "wicking," "wicking ability," "capillary action," "capillary pull," "wicking strength" and the like. Felt has excellent, predictable, andconsistent wicking capabilities, and various types of felt can be used for both the wick and reservoir. Fibrous bundles are also excellent choices for wick 50 and reservoir 28. For example, one commercial material suitable for wick 50 is bondedpolyolefin fiber bundle with a density of 0.27 g/cc (supplied by Filtrona Fibertec, 1625 Ashton Park Drive, Colonial Heights, Va., 23834) Filtrona sample no. 05-052. One commercial material suitable for reservoir 28 is bonded polyolefin fiber bundlewith a density of 0.122 g/cc (supplied by Filtrona Fibertec, 1625 Ashton Park Drive, Colonial Heights, Va., 23834) Filtrona sample no. 03-368A. One of skill in the art would readily recognize, however, that many other materials can be used for the wickand the reservoir, such as cotton, polyester, fibers (including glass fibers), nylon, polypropylene and many others. The materials should be chosen such that the wick has a greater capillary action or wicking strength than the reservoir, and such thatthe fur of the animal draws fluid from the wick by capillary action upon contact.
The selection of materials for the wick and reservoir may depend upon the substance being dispensed, e.g., its viscosity, volatility, hydrophilicity, surface tension and other fluid properties. Liquids dispensed with dispenser 20 are typicallynon-volatile so that they do not evaporate from wick 50, but instead are only transferred from wick 50 upon contact. Generally speaking, if felt or a fibrous bundle is used for reservoir 28 and wick 50, the capillary action or wicking ability increaseswith increasing density of the substance. However, the wicking properties of wick 50 and reservoir 28 can vary with the type of substance being dispensed. The exemplary wick and reservoir material identified in the previous paragraph were tested andperformed satisfactorily when the substance being dispensed was spinosad formulation M08-AH00277-7-1 (lot X-51908) Elanco Animal Health, 2001 West Main Street, Greenfield, Ind. 46140, as detailed in the examples below.
With reference to FIG. 4, an alternate embodiment of a dispenser 120 is shown in which reservoir 128 and wick 150 are formed from a unitary material. As shown, wick 150 is compressed and "squeezed" by sleeve 124. That is, sleeve 124 exerts acompressive force on wick 150. The compression of wick 150 increases its density and thus increases the number of pores per unit volume. This in turn tends to increase its wicking strength or capillary attraction. In certain circumstances, it may beadvantageous to manufacture the reservoir and wick from a single piece of material, and the dispenser shown in FIG. 4 is an example of how that can be accomplished.
Furthermore, it should be appreciated that because the disclosed embodiments work by capillary action, the wick need not be placed at the bottom of the dispenser and the dispenser need not be attached to the animal such that the wick is pointingdownward. With reference to FIG. 5, dispenser 220 includes a wick 250 that extends laterally from the side of shell 222. The capillary forces that drive fluid flow in the illustrated embodiments can work against gravity, if so desired. However, in theembodiment illustrated in FIG. 1, skirt 52 partially surrounds or circumscribes the sleeve 24 and wick 50, which tends to prevent rain water from contacting wick 50, either directly or dripping from shell 22. If excessive rain water were to fall uponwick 50 or drip onto it from the sides of the dispenser, such could dilute the strength of the pesticide that is contained in the dispenser or otherwise undesirably alter the wicking properties of the device.
Since the dispenser disclosed herein delivers fluid by wicking, as opposed to gravity or pressure differentials, a wide variety of pesticides can be used. These include but are not limited to various avermectins, benzimidazoles, milbemycins,carbamates, organophosphates, phenylpyrazoles, amidines, insect growth regulators, juvenile hormones, nicotinoids, pyrroles, pyrethrins, pyrethroids and naturalytes (i.e. the spinosyn family). Representative compounds may include abamectin, doramectin,eprinomectin, selamectin, alphamethrin, amitraz, coumaphos, ivermectin, deltamethrin, cyhalothrin, diazinon, cyromazine, cypermethrin, milbemycin, cyfluthrin, cyloprothrin, famphur, fenthion, fenvalerate, flucythrinate, flumethrin, hexaflumuron, lindane,lufenuron, malathion, methoprene, metriphonate, moxidectin, permethrin, pyrethrin, pyrethrum, phosmet, pirimiphos, chlorvinphos, rotenone, propetamphos, tetrachlorvinphos, zetacypermethrin, coumaphos and spinosad, among others.
FIGS. 6 and 7 illustrate embodiments in which multiple substances can be dispensed. Exemplary substances capable of being dispensed together in accordance with the present invention include, but are not limited to, lambdacyhalothrin,gamma-cyhalothrin and imidacloprid. With reference to FIG. 6, dispenser 320 includes reservoir 328 in fluid communication with wick 350 to dispense a first substance by capillary action. Similarly, reservoir 329 is in fluid communication with wick 351to dispense a second substance by capillary action. Shell 322 includes a divider 360 that maintains reservoir 328 separate from reservoir 329. In FIG. 7, dispenser 420 includes centrally disposed reservoir 428 in fluid communication with wick 430 andannular reservoir 432 in fluid communication with wick 434. Dispenser 420 includes an outer shell 422, similar to shell 22 described with reference to FIG. 1, and an inner shell 460 that separates the two reservoirs. As shown in FIG. 7, both wicks havesurfaces thereof exposed for contact with the animal to which dispenser 420 is attached. A skirt 452 may prevent rain water from reaching wicks 430 and 434.
Specific examples embodying the technology described above are set forth below.
Objective: In this example two prototype devices similar in structure to device 20 described above were tested to determine the fluid payout difference between a dispenser that had repeated mechanical contact compared to an identical dispenserleft in a static position.
Prototype Description: The dispensers used in this example were fabricated from a plastic shell and insert materials used in a marker manufactured by Sanford Corp. under the Accent.RTM. brand. The reservoir was made of Formax 609, AcetalCopolymer from Chem Polymer Corporation and a wick formed from bonded polyolefin fiber bundle with a density of 0.27 g/cc (supplied by Filtrona Fibertec, 1625 Ashton Park Drive, Colonial Heights, Va., 23834) Filtrona sample no. 05-052. The devices werefilled with approximately 8 cc of spinosad formulation M08-AH00277-7-1 (lot X-51908) and weight was recorded.
An attachment means similar to attachment means 36 was grafted to the top of the dispenser shell that was used for the repeated mechanical contact, and this dispenser was attached to a mechanical cow ear having faux fur. The other dispenser(which was maintained stationary) had no attachment means, only a plug to seal it at the top, which explains the discrepancy in weights between the two dispensers.
Ohaus Explorer Pro analytical balance Mechanical cow ear (custom manufactured by Aircom Mfg., Inc.) Observation Method:
One device was attached to the mechanical cow ear and allowed to run at an approximate rate of one cycle per 7 seconds. Each cycle consists of the ear flicking backward and making momentary contact with the faux fur. The other device wasplaced in a vertical and stationary position and left undisturbed with the exception of weight recording. The devices were weighed at regular intervals and weights were recorded.
After one hour of cycling, there was visible evidence of the spinosad formulation on the faux fur. The odor of the formulation could also be detected on the faux fur. The devices were checked again at 24 hours. Results are recorded in Table1, below.
After the 24 hour check the test was re-started. The weight of the devices were checked hourly for five hours. The fur was changed to a clean patch at each hour in an attempt to obtain a more consistent payout. The results presented in Table1 show that the device that repeatedly contacted the faux fur dispensed at an hourly rate of approximately 55 times greater than the dispenser that was held stationary.
TABLE-US-00001 TABLE 1 Weight Loss Results Moving device Static device (grams) (grams) Start weight 16.97 13.36 Weight @ 3.5 hrs 16.891 13.358 3.5 hr loss 0.079 0.002 Weight @ 24 hrs 16.712 13.341 24 hr loss 0.258 0.019 Start weight 16.71213.331 Weight @1 hr 16.704 13.331 1 hr loss 0.008 0 Weight @ 2 hrs 16.693 13.331 2 hr loss 0.019 0 Weight @ 3 hrs 16.685 13.331 3 hr loss 0.027 0 Weight @ 4 hrs 16.676 13.33 4 hr loss 0.036 0.001 Weight @ 5 hrs 16.657 13.33 5 hr loss 0.055 0.001 Averageloss/hr 0.011 0.0002
The objective of this test was to determine if the dispenser payout rate can be altered by changing the amount of surface area of the wick exposed at the tip of the device, i.e., whether the rate can be altered by increasing the amount by whichthe wick protrudes from the opening.
Prototype Description: A dispenser as described above with respect to Example 1 was used. The dispenser was filled with approximately 8 cc of spinosad formulation M08-AH00277-7-1 (lot X-51908) and weight was recorded.
As in Example 1, the dispenser used for the repeated mechanical contact had an attachment means, whereas the stationary device did not.
Ohaus Explorer Pro analytical balance Aircom mechanical cow ear Observation Method:
The dispenser initially had its wick protruding about 1/4'' from the opening of the dispenser. It was attached to the mechanical cow ear and allowed to run at an approximate rate of one cycle per 7 seconds. Each cycle consists of the earflicking backward and making momentary contact with the faux fur. The device was allowed to cycle for two hours. Weight was recorded at each hour. At the end of the two hours, the device was removed from the mechanical ear and approximately 1/2 of theprotruding portion of its wick was removed. Weight was recorded and the above sequence was repeated. At the end of the second two hour cycle, the device was once again removed from the mechanical ear and the wick was cut flush with the end of thedevice. Weight was recorded and the above sequence was repeated.
Shortening the wick and accordingly decreasing the surface area available for contact produces a measurable effect on payout. The payout decreased by a little more than 50% when the amount of the wick protruding was reduced by about half. Thedispenser then lost very little or no weight when the wick was cut off flush with the opening. It was also difficult to detect any of the liquid spinosad formulation on the faux fur, whereas the liquid spinosad could be easily seen on the samples takenwith an exposed wick. Table 2, below, illustrates these results.
TABLE-US-00002 TABLE 2 Weight Loss Results Unaltered Wick Half Cut Wick Flush Cut Wick (grams) (grams) (grams) Start weight 16.63 16.558 16.48 Weight @ 1 hr 16.619 16.554 16.479 1 hr loss 0.011 0.004 0.001 Weight @ 2 hrs 16.607 16.55 16.478 2 hrloss 0.023 0.008 0.002 Average loss/hr 0.0115 0.004 0.001
Determine whether an additional prototype will payout fluid at a rate similar to the dispenser of Example 1 under similar conditions.
A prototype similar to that described in Example 1 was used. The device was filled with approximately 8 cc of spinosad formulation M08-AH00277-7-1 (lot X-51908) and weight was recorded.
Ohaus Explorer Pro analytical balance Aircom mechanical cow ear Observation Method:
The device was attached to the mechanical cow ear and allowed to run at an approximate rate of one cycle per 7 seconds. Each cycle consists of the ear flicking backward and making momentary contact with the faux fur. The device was weighedhourly and weights were recorded. The mechanical ear was moved to a clean patch of faux fur at each hour.
After one hour of cycling, there was visible evidence of the spinosad formulation on the faux fur. The odor of the formulation could also be detected on the faux fur. Results are recorded in Table 3, below.
TABLE-US-00003 TABLE 3 Weight Loss Results Device weight Device weight (grams) (grams) Day 1 Day 6 Start weight 16.712 16.473 Weight @1 hr 16.704 16.463 1 hr loss 0.008 0.01 Weight @ 2 hrs 16.693 16.452 2 hr loss 0.019 0.021 Weight @ 3 hrs16.685 16.438 3 hr loss 0.027 0.035 Weight @ 4 hrs 16.676 16.424 4 hr loss 0.036 0.049 Weight @ 5 hrs 16.657 13.33 5 hr loss 0.055 0.067 Average loss/hr 0.011 0.0134
Determine if elevated temperature causes spinosad formulation to leak from the dispenser in droplet form. (Weight loss due to evaporation was not considered in this test.)
The prototype was similar to that described in Example 1. The dispenser was filled with approximately 8 cc of spinosad formulation M08-AH00277-7-1 (lot X-51908) and weight was recorded.
VWR model 1410 vacuum chamber/oven Observation Method:
The dispenser was placed in a vertical orientation inside the oven and the oven temperature was set to 50° C. A polished stainless steel slide was placed below the device to help identify any potential dripping. The device was observedfor 24 hours.
The device was visually checked several times over the course of 24 hours. No dripping was observed. In addition, drops did not form on the end of the wick nor at the bottom of the reservoir. The dispenser appeared to retain all the liquid. At the end of the test, the dispenser was removed from the oven and tested on a piece of paper to determine if the wick had dried out. Initially, the wick felt a bit dry as it was applied to the paper. However, after minimal contact with the paper, thedispenser began to pay out liquid to the paper.
While a preferred embodiment incorporating the principles of the present invention has been disclosed hereinabove, the present invention is not limited to the disclosed embodiments. Instead, this application is intended to cover any variations,uses, or adaptations of the invention using its general principles. Further, this application is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this invention pertains andwhich fall within the limits of the appended claims.
Field of SearchWith means to supply treatment material to the animal; e.g., antivermin treatment, flame, attractant
Means engaging animal directly; e.g., daubing or rubbing means
Having capillary treatment supply wick
Yieldable, horizontally extending web or rod adapted to slide over animal passing thereunder
Having distinct treatment reservoir
Releasable chemical agent (e.g., medicine, deodorant, etc.)
Having means passing through the animal skin; e.g., ear tag