U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Modified DMO enzyme and methods of its use

Patent 7884262 Issued on February 8, 2011. Estimated Expiration Date: Icon_subject June 5, 2027. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Detoxification of chlorinated aromatic compounds by organism NRRL B-18086
Patent #: 4816403
Issued on: 03/28/1989
Inventor: Roy

Microorganisms
Patent #: 5445962
Issued on: 08/29/1995
Inventor: Atallah, et al.

Compositions and methods for detection of 2,4-dichlorophenoxyacetic acid and related compounds
Patent #: 5656422
Issued on: 08/12/1997
Inventor: Crawford, et al.

Herbicides of the auxin type for treating transgenic crop plants
Patent #: 5670454
Issued on: 09/23/1997
Inventor: Grossmann, et al.

Promoter (FLt) for the full-length transcript of peanut chlorotic streak caulimovirus (PCLSV) and expression of chimeric genes in plants
Patent #: 5850019
Issued on: 12/15/1998
Inventor: Maiti, et al.

Methods and materials for making and using transgenic dicamba-degrading organisms
Patent #: 7022896
Issued on: 04/04/2006
Inventor: Weeks, et al.

Methods and materials for making and using transgenic dicamba-degrading organisms Patent #: 7105724
Issued on: 09/12/2006
Inventor: Weeks, et al.

Inventors

Assignee

Application

No. 11758657 filed on 06/05/2007

US Classes:

800/278METHOD OF INTRODUCING A POLYNUCLEOTIDE MOLECULE INTO OR REARRANGEMENT OF GENETIC MATERIAL WITHIN A PLANT OR PLANT PART

Examiners

Primary: O Hara, Eileen B

Attorney, Agent or Firm

Foreign Patent References

  • 2165036 CA 06/01/1996
  • WO 97/41228 WO 11/01/1997
  • WO 98/45424 WO 10/01/1998
  • WO 02/068607 WO 09/01/2002
  • WO 03/034813 WO 05/01/2003
  • WO 2005/107437 WO 11/01/2005
  • 2007/143690 WO 12/01/2007
  • WO 2007/146706 WO 12/01/2007
  • WO 2008/048964 WO 04/01/2008
  • WO 2008/051633 WO 05/01/2008
  • 2008/105890 WO 09/01/2008

International Classes

A01H 5/00
C12N 5/04
C12N 15/82
C07H 21/04

Abstract

The invention provides a modified variant of dicamba monooxygenase (DMO). The invention relates to the unexpected finding that cells expressing this DMO exhibit high levels of tolerance to the herbicide dicamba. Compositions comprising DMO-encoding nucleic acids and methods of use are provided.

Other References

  • Notice of Allowance regarding U.S. Appl. No. 11/758,653, dated Oct. 5, 2010.
  • Response to Official Action regarding U.S. Appl. No. 11/758,660, dated Sep. 27, 2010.
  • Notice of Allowance regarding U.S. Appl. No. 11/758,656, dated Oct. 4, 2010.
  • U.S. Appl. No. 12/875,747, Weeks et al., filed Sep. 3, 2010.
  • Notice of Allowance regarding U.S. Appl. No. 11/758,659, dated Aug. 3, 2010.
  • Amendment and Response to Final Office Action regarding U.S. Appl. No. 11/758,656, dated Aug. 16, 2010.
  • Declaration of Yuechun Wan Under 37 C.F.R. §1.132, dated Aug. 11, 2010, U.S. Appl. No. 10/330,662.
  • Amendment and Response to Final Office Action regarding U.S. Appl. No. 11/758,653, dated Aug. 16, 2010.
  • Notice of Allowance regarding U.S. Appl. No. 10/330,662, dated Jul. 12, 2010.
  • Office Action regarding U.S. Appl. No. 11/758,660, dated Apr. 28, 2010.
  • Amendment and Response to Office Action regarding U.S. Appl. No. 11/758,659, dated May 24, 2010.
  • Final Office Action regarding U.S. Appl. No. 11/758,656, dated Apr. 14, 2010.
  • Final Office Action regarding U.S. Appl. No. 11/758,653, dated Jun. 24, 2010.
  • Amendment and Response to Office Action regarding U.S. Appl. No. 11/758,653, dated Mar. 29, 2010.
  • Amendment and Remarks regarding U.S. Appl. No. 10/330,662, dated May 4, 2010.
  • Interview Summary regarding U.S. Appl. No. 10/330,662, dated Mar. 19, 2010.
  • Office Action regarding U.S. Appl. No. 10/330,662, dated Jan. 11, 2010.
  • Amendment and Remarks regarding U.S. Appl. No. 10/330,662, dated Sep. 24, 2009.
  • Final Office Action regarding U.S. Appl. No. 10/330,662, dated Apr. 24, 2009.
  • Amendment and Remarks regarding U.S. Appl. No. 10/330,662, dated Jan. 9, 2009.
  • Office Action regarding U.S. Appl. No. 10/330,662, dated Jul. 9, 2008.
  • Amendment and Response to Office Action regarding U.S. Appl. No. 10/330,662, dated Mar. 20, 2008.
  • Declaration of Donald P. Weeks regarding U.S. Appl. No. 10/330,662, dated Feb. 20, 2008.
  • Office Action regarding U.S. Appl. No. 10/330,662, dated Sep. 21, 2007.
  • Amendment regarding U.S. Appl. No. 10/330,662, dated Jul. 20, 2007.
  • Amendment and Response to Office Action regarding U.S. Appl. No. 10/330,662, dated Jul. 9, 2007.
  • Final Office Action regarding U.S. Appl. No. 10/330,662, dated Jan. 10, 2007.
  • Amendment and Response to Office Action regarding U.S. Appl. No. 10/330,662, dated Oct. 18, 2006.
  • Declaration of Donald P. Weeks regarding U.S. Appl. No. 10/330,662, dated Oct. 18, 2006.
  • Interview Summary regarding U.S. Appl. No. 10/330,662, dated Sep. 13, 2006.
  • Office Action regarding U.S. Appl. No. 10/330,662 dated Apr. 18, 2006.
  • Thompson et al., “Soybean tolerance to early preplant applications of 2,4-D ester, 2,4-D amine, and dicamba,” Weed Technology, 21:882-885, 2007.
  • Sprague, “Avoid herbicide spray tank contamination,” IPM News, ipmnews.msu.edu/fieldcrop/tabid/56, Mar. 24, 2010.
  • Office Action regarding U.S. Appl. No. 11/758,659 dated Nov. 24, 2009.
  • Response to Office Action regarding U.S. Appl. No. 11/758,656 dated Dec. 17, 2009.
  • Office Action regarding U.S. Appl. No. 11/758,656 dated Sep. 15, 2009.
  • Office Action regarding U.S. Appl. No. 11/758,653 dated Dec. 29, 2009.
  • Wang, “Characterization of cellular and enzymatic degradation of dicamba by Pseudomonas maltophilia, Strain DI-6,” Thesis, University of Nebraska, Aug. 1996.
  • Wang et al., “A three-component enzyme system catalyzes the O demethylation of the herbicide dicamba in Pseudomonas maltophilia DI-6,” Applied and Environmental Microbiology, 63(4):1623-1626, 1997.
  • Schroeder et al., “Soft red winter wheat (Triticum aestivum) response to dicamba and dicamba plus 2,4-D,” Weed Technology, 3:67-71, 1989.
  • Sarpe et al., “Researches on resistance of maize hybrids and inbred lines to the herbicides based on 2,4-D and dicamba,” Fragmenta Herbologica Jugoslavica, 16(1-2):299-305, 1987.
  • Peniuk et al., “Physiological investigations into the resistance of a wild mustard (Sinapis arvensis L.) biotype to auxinic herbicides,” Weed Research, 33:431-440, 1993.
  • Mason et al., “The electron-transport proteins of hydroxylating bacterial dioxygenases,” Ann. Rev. of Microbiology, 46:277-305, 1992.
  • Markus et al., “Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS,” J. of Biol. Chem., 261(27):12883-12888, 1986.
  • Magnusson et al., “Tolerance of soybean (Glycine max) and sunflower (Helianthus annuus) to fall-applied dicamba,” Weed Sci., 35:846-852, 1987.
  • Krueger et al., “Use of dicamba-degrading microorganisms to protect dicamba susceptible plant species,” J. of Agri. and Food Chem., 39(5):1000-1003, 1991.
  • Gurbiel et al., “Active site structure of Rieske-type prteins: electron nuclear double resonance studies of isotopically labeled phthalate dioxygenase from Pseudomonas cepacia and Rieske protein from rhodobacter capsulatus and molecular modeling studies of a Rieske center,” Biochemistry, 35(24):7834-7845, 1996 (Abstract).
  • Gibson et al., “Aromatic hydrocarbon dioxygenases in environmental biotechnology,” Current Opinion in Biotechnology, 11:236-243, 2000.
  • Fukumori et al., “Purification and characterization of 2,-dichlorophenoxyacetate/α-ketoglutarate dioxygenase,” J. Biol. Chem., 268:24311-24317, 1993.
  • Fogarty et al., “Microbiological degradation of the herbicide dicamba,” J. of Industrial Microbiology, 14:365-370, 1995.
  • Dehmel et al., “Cloning, nucleotide sequence and expression of the gene encoding a novel dioxygenase involved in metabolism of carboxydiphenyl ethers in Pseudomonas pseudoalcaligenes POB310,” Arch. Microbiol., 163:35-41, 1995.
  • Butler et al., “Structure-function analysis of the bacterial aromatic ring-hydroxylating dioxygenases,” Advances in Microbial Physiology, 38:47-85, 1997.
  • Bernhardt et al., “A 4-methoxybenzoate O-demethylase from Pseudomonas putida. A new type of monoxygenase system,” Eur. J. Biochem., 57(1):241-256, 1975.
  • Batie et al., “Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia,” J. of Bio. Chem., 262(4):1510-1518, 1987.
  • Batie et al., “Phthalate dioxygenase reductase and related flavin-iron-sulfur containing electron transferases,” In: Chemistry and Biochemistry of Flavoproteins, Muller (Ed.), CRC Press, Boca Raton, FL, pp. 543-556, 1992.
  • U.S. Appl. No. 12/440,173, filed Mar. 5, 2009, Bhatti et al.
  • Baker, “Response of cotton (Gossypium hirsutum) to preplant-applied hormone-type herbicides,” Weed Technology, 7:150-153, 1993.
  • Al-Khatib et al., “Foliar absorption and translocation of dicamba from aqueous solution and dicamba-treated soil deposits,” Weed Technology, 6:57-61, 1992.
  • “Banvel Herbicide,” In: Crop Protection Reference, 11th Edition, pp. 1803-1821, 1995.
  • Weeks et at, “Characterization of a bacterial system capable of degrading dicamba and evaluation of its potential in the development of herbicide-tolerant crops,” J. of Cellular Biochemistry, Supplement 18A:91, 1994.
  • Spencer et al., “Segregation of transgenes in maize,” Plant Molecular Biology, 18:201-210, 1992.
  • Khalil et al., “Plasmid-mediated catabolism of dicamba by Pseudomonsas species strain PXM,” Microbios, 102:183-191, 2000.
  • Xiaoman et al., “Study of BRCA1 gene in hereditary breast and ovarian cancer,” Chin. Med. Sci. J., 14(4):195-199, 1999.
  • Wada et al., “Molecular characterization of coagulation factor XII deficiency in a Japanese family,” Thromb. Haemost., 90(1):59-63, 2003.
  • Svab et al., “Stable transformation of plastids in higher plants,” Proc. Natl. Acad. Sci. USA, 87(21):8526-8530, 1990.
  • Svab et al., “Aminoglycoside-3″-adenyltransferase confers resistance to spectinomycin and streptomycin in Nicotiana tabacum ,” Plant Mol. Biol., 14:197, 1990.
  • Mitsuhara et al., “Efficient promoter cassettes for enhanced expression of foreign genes in dicotyledonous and monocotyledonous plants,” Plant Cell Physiol., 37:49-59, 1996.
  • Krueger et al., “Isolation and identification of microorganisms for the degradation of dicamba,” J. Agric. Food Chem., 37:534-538, 1989.
  • Koncz et al., “The promoter of TL-DNA gene 5 controls the tissue-specific expression of chimaeric genes carried by a novel type of Agrobacterium binary vector,” Mol. Gen. Genet., 204:383-396, 1986.
  • Hoffman et al., “Type I hyperlipoproteinemia due to a novel loss of function mutation of lipoprotein lipase, Cys(239)—>Trp, associated with recurrent severe pancreatitis,” J. Clin. Endocrinol. Metab., 85(12):4795-4798, 2000.
  • Herman et al., “A three-component dicamba O-demethylase from Pseudomonas maltophilia, strain DI-6: gene isolation, characterization, and heterologous expression,” J. Biol. Chem., 280:24759-24767, 2005.
  • Hajdukiewicz et al., “The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation,” Plant Mol. Biol., 25:989-994, 1994.
  • Desvaux et al., “Genomic analysis of the protein secretion systems in Clostridium acetobutylicum ATCC 824,” Biochimica et Biophysica Acta, 1745:223-253, 2005.
  • Coruzzi et al., “Nucleotide sequences of two pea cDNA clones encoding the small subunit of ribulose 1,5-bisphosphate carboxylase and the major chlorophyll a/b-binding thylakoid polypeptide ,” J. Biol. Chem., 258(3):1399-1402, 1983.
  • Cork et al., “Microbial transformations of herbicides and pesticides,” Adv. Appl. Microbiol., 36:1-66, 1991.
  • Cork et al., “Detection, isolation, and stability of megaplasmid-encoded chloroaromatic herbicide-degrading genes within Pseudomonas species,” Adv. Appl. Microbiol, 40:289-321, 1995.
  • Carrington et al., “Cap-independent enhancement of translation by a plant potyvirus 5′ nontranslated region,” J. Virology, 64:1590-1597, 1990.
  • Becker et al., “New plant binary vectors with selectable markers located proximal to the left T-DNA border,” Plant Mol. Biol., 20:1195-1197, 1992.
  • Behrens et al., “Dicamba resistance: enlarging and preserving biotechnology-based weed management strategies,” Science, 316(5828):1185-1188, 2007.
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?