U.S. patents available from 1976 to present.
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Method of treating movement disorders using barbituric acid derivatives

Patent 7655667 Issued on February 2, 2010. Estimated Expiration Date: Icon_subject February 16, 2026. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Abstract Claims Full Text

Patent References

1960170

2673205

3679683

3711607

3900475

3904627

3919427

3930006

N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same
Patent #: 3948896
Issued on: 04/06/1976
Inventor: Vida

Method of making barbituric acid derivatives
Patent #: 4029662
Issued on: 06/14/1977
Inventor: Vida

More ...

Inventor

Assignee

Application

No. 11355339 filed on 02/16/2006

US Classes:

514/270Barbituric acid or derivative (including thioanalogs)

Examiners

Primary: Jiang, Shaojia Anna
Assistant: Olson, Eric S

Attorney, Agent or Firm

Foreign Patent References

  • 946 804 DE 08/01/1956
  • 11 00 639 DE 03/01/1961
  • 11 03 339 DE 03/01/1961
  • 1939787 DE 02/01/1970
  • 2622981 DE 12/01/1977
  • 4028040 DE 03/01/1992
  • 726252 EP 08/01/1996
  • 1 083 172 EP 03/01/2001
  • 966098 GB 08/01/1959
  • WO 99/18084 WO 04/01/1999
  • WO 01/39779 WO 06/01/2001
  • WO 01/79185 WO 10/01/2001
  • WO 02/07729 WO 01/01/2002
  • WO 03/063872 WO 08/01/2003
  • WO 2004/052350 WO 06/01/2004
  • WO 2006/003651 WO 01/01/2006
  • WO 2006/026095 WO 03/01/2006

International Classes

A61K 31/515
C07D 239/62
C07D 239/64

Abstract



A method of treating movement disorders comprises administering to a human or animal subject in need of treatment a therapeutically effective amount of at least one compound according to the following formula:

wherein R3 and R4 are each independently selected from the group consisting of lower alkyl, phenyl and lower alkyl substituted phenyl, and R1 and R2 are each independently either a hydrogen atom or a radical of the formula

wherein R5 and R6 are each independently selected from the group consisting of H, lower alkyl, phenyl and lower alkyl substituted phenyl, its pharmaceutically acceptable salts, prodrugs, and metabolites thereof.

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