Pigment protein from

Patent 7504491 Issued on March 17, 2009. Estimated Expiration Date:

June 10, 2023. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Nucleic acids encoding non aggregating fluorescent proteins and methods for using the same Patent #: 6969597
Issued on: 11/29/2005
Inventor: Lukyanov, et al.

Inventors

Assignee

Application

No. 10516317 filed on 06/10/2003

US Classes:

536/23.1DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)

Examiners

Primary: Naokes, Suzanne M.

Attorney, Agent or Firm

GreenBlum & Bernstein, P.L.C.

Foreign Patent References

1512744 EP 03/01/2005
1512745 EP 03/01/2005
00/34319 WO 06/01/2000
00/34526 WO 06/01/2000
01/27150 WO 04/01/2001
03/104461 WO 12/01/2003
2004/018671 WO 03/01/2004

International Classes

C07H 21/04
C07K 1/00

Abstract

An object of the present invention is to provide a chromoprotein derived from Cnidopus japonicus. The present invention provides a chromoprotein derived from Cnidopus japonicus having the following properties: (1) the absorption maximum wavelength is 610 nm, and fluorescence is not emitted; (2) the molar absorption coefficient is 66,700 at 610 nm; and (3) the pH sensitivity of light-absorbing property is stable at between pH 4 and pH 10.

Other References

Ngo et al. in “The Protein Folding Problem and Tertiary Structure Prediction,” 1994, Merz et al. (ed.), Birkhauser, Boston, MA, pp. 433 and 492-495.
Lukyanov et al., US 6969597, Nov. 2005, SEQ ID No. 1 sequence alignment Result 1, database: Issued_—Patents_—NA.
Lukyanov et al., US 6969597, Nov. 2005, SEQ ID No. 2 sequence alignment Result 1, database: Issued_—Patents_—NA.
Chan et al., 2006, Journal of Biological Chemistry, vol. 281, No. 49, pp. 37813-37819.
R.Y. Tsien, Ann. Rev. Biochem., vol. 67, 1998, pp. 509-544.
A. Miyawaki et al., Midoriishi, Mar. 2002, No. 13, pp. 1-4.
U.S. Appl. No. 10/516,314 to Miyawaki et al., which was filed on Dec. 10, 2004.
U.S. Appl. No. 10/525,365 to Miyawaki et al., which was filed on Feb. 23, 2005.
Hideaki Mizuno et al., “Red Fluorescent Protein from Discocoma as a Fusion Tag and a Partner for Fluorescence Resonance Energy Transfer”, Biochemistry, American Chemical society, vol. 40, No. 8, pp. 2502-2510, 2001.
Y. A. Labas et al., “Diversity and evolution of the green fluorescent protein family”, Proceedings of the National Academy of Science of USA, vol. 99, No. 7 pp. 4256-4261, 2002.
U.S. Appl. No. 10/516,214 to Miyawaki et al., filed Dec. 10, 2004.