U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Methods for modifying electrical currents in neuronal circuits

Patent 7283861 Issued on October 16, 2007. Estimated Expiration Date: Icon_subject April 30, 2022. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventor

Application

No. 10135137 filed on 04/30/2002

US Classes:

600/411, Combined with therapeutic or diverse diagnostic device600/427, Combined with therapeutic or diagnostic device600/436, Nuclear radiation (e.g., radioactive emission, etc.)600/544, Detecting brain electric signal601/2, Ultrasonic600/2, Combined with other radiant or wave energy source (e.g., electromagnetic, thermal, microwave etc.)600/9, MAGNETIC FIELD APPLIED TO BODY FOR THERAPY607/116, Placed in body600/407, Detecting nuclear, electromagnetic, or ultrasonic radiation600/439, With therapeutic device600/383, Head or eye600/25, SURGICALLY IMPLANTED VIBRATORY HEARING AID514/1225 or more peptide repeating units in known peptide chain structure

Examiners

Primary: Smith, Ruth S.

Attorney, Agent or Firm

International Class

A61N 7/00

Abstract

Disclosed herein are methods for modifying electrical currents in brain circuits through the simultaneous use of focused ultrasound pulse (FUP) and an existing brain-imaging system, such as a functional magnetic resonance imaging (fMRI) system. The methods are used for research, treatment and diagnosis of psychiatric, neurological, and neuroendocrine disorders whose biological mechanisms include brain circuits. The methods include the simultaneous steps of applying FUP to a live neuronal circuit within a brain and monitoring a brain image produced by a brain imaging system during the application of FUP.

Other References

  • Rauch et al., “Clinical Neuroimaging in Psychiatry”, Harvard Review of Psychiatry (Mar./Apr. 1995) vol. 2, No. 6, pp. 297-312.
  • Clement et al., “A hemispher array for non-invasive brain therapy and surgery”, Physics in Medicine & Biology, (Dec. 2000), vol. 45, No. 12, pp. 3707-3719.
  • George et al., “Transcranial Magnetic Stimulation: A Neuropsychiatric Tool for the 21st Century”, Journal of Neuropsychiatry and Clinical Neuroscience (fall 1996), vol. 8, No. 4, pp. 373-382.
  • Barlow et al., “The Risk of Seizures after Receipt of Whole-Cell Pertussis or Measles, Mumps, and Rubella Vaccine”, New England Journal of Medicine (Aug. 30, 2001), vol. 345, No. 9, pp. 656-661.
  • Roth et al., “Deep Brain Stimulation in Neuropsychiatric Disorders”, Current Psychiatry Report (Oct. 2001), vol. 3, No. 5, pp. 366-372.
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