U.S. patents available from 1976 to present.
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Methods for extracting similar expression patterns and related biopolymers

Patent 7277798 Issued on October 2, 2007. Estimated Expiration Date: Icon_subject December 14, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Systems and methods for characterizing a biological condition or agent using precision gene expression profiles Patent #: 6692916
Issued on: 02/17/2004
Inventor: Bevilacqua ,   et al.

Inventors

Assignee

Application

No. 09739525 filed on 12/14/2000

US Classes:

702/19, Biological or biochemical435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/6, Involving nucleic acid702/27, Molecular structure or composition determination703/11, Biological or biochemical382/218Comparator

Examiners

Primary: Shukla, Ram R.
Assistant: DeJong, Eric S.

Attorney, Agent or Firm

Foreign Patent References

  • 1 037 158 EP 09/01/2000
  • 9068994 JP 03/01/1996
  • 10-160419 JP 12/01/1996
  • WO 00/24936 WO 05/01/2000

International Classes

C12Q 1/00
C12Q 1/68
G01N 31/00
G06G 7/48

Abstract

The present invention provides methods for extracting similar expression patterns and related biopolymers considering natures that are characteristic of expression data of, for example, genes. A segment of experiment cases which includes an expression of interest is selected as a search range among an expression pattern of a reference gene or the like. By comparing the selected segment of the expression pattern with expression patterns of a group of candidate genes or the like, genes having an expression pattern with at least a partial similarity are searched from the group of candidate genes. A partially taken out curve (a part of an, expression pattern) is transferred to overlap an expression pattern curve of a candidate gene to search expression patterns with a similar pattern shape.

Other References

  • “Estimation of Gene Functions”, Experimental Medicine (Sep. 1990), vol. 17, No. 13, pp. 1670-1673, and 1692, (English abstract only).
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  • van Steensel, M. AM. et al., “Probing the Gene expression Database for candidate genes,” European Journal of Human Genetics, vol. 7 (1999). pp. 910-919.
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