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Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer

Patent 7192612 Issued on March 20, 2007. Estimated Expiration Date: Icon_subject July 6, 2024. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventors

Assignee

Application

No. 10886159 filed on 07/06/2004

US Classes:

424/729, Containing or obtained from Camellia (e.g., tea, including green or black tea, etc.)424/760, Containing or obtained from Capsicum (e.g., chili pepper, cayenne pepper, red pepper, etc.)424/468, Sustained or differential release type514/456, Bicyclo ring system having the hetero ring as one of the cyclos (e.g., chromones, etc.)514/732, Polycyclo ring system (e.g., naphthols, etc.)514/738, Polyhydroxy426/638Spice, herb, or condiment thereof

Examiners

Primary: Tate, Christopher R.

Attorney, Agent or Firm

Foreign Patent References

  • 0089710 EP 09/01/1983
  • 282127 EP 09/01/1988
  • 2168974 GB 07/01/1986
  • 2168975 GB 07/01/1986
  • 2168976 GB 07/01/1986

International Classes

A51K 36/82
A61K 36/81
A61K 9/22
A61K 31/35
A61K 31/05

Abstract

The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of therapeutically effective amount of catechins, a group of polyphenols found in green tea, and Capsicum extracts. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC). The unique compositions of the invention contain various combinations of the catechins and Capsicum extracts, in combination with each other or other therapeutic agents and are used to treat primary and metastatic cancers in humans. The invention also encompasses the varying modes of administration of the therapeutic compounds, including a formulation which may be used as a therapeutic compound for the treatment of cancer or as a dietary supplement for the prevention of cancer.

Other References

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