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US Patent 7115281 - Processes for the preparation of oral dosage formulations of modafinil

US Patent Issued on October 3, 2006
Estimated Patent Expiration Date: Icon_subject July 8, 2023Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

The invention relates to processes for preparing, and pharmaceutical compositions of, modafinil dosage forms for oral administration. The dosage forms include a mixture of coarse and fine particles of modafinil. The process for preparing modafinil oral dosage forms includes forming a dosage form that includes about 7%–25% by weight of modafinil particles having diameters greater than 220 μm and about 75%–93% by weight of modafinil particles having diameters less than 220 μm.

Inventors

Assignee

Application

No. 10616240 filed on 07/08/2003

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/464, Tablets, lozenges, or pills424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/452, With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.)424/457, Sustained or differential release514/618Sulfur in R

Field of Search

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/457, Sustained or differential release424/452, With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.)424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/464Tablets, lozenges, or pills

Examiners

Primary: Webman, Edward J.

Attorney, Agent or Firm

Foreign Patent References

  • 2293103 GB 03/01/1996

International Classes

A61K 9/16
A61K 9/26
A61K 9/48

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