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AbstractThe invention relates to processes for preparing, and pharmaceutical compositions of, modafinil dosage forms for oral administration. The dosage forms include a mixture of coarse and fine particles of modafinil. The process for preparing modafinil oral dosage forms includes forming a dosage form that includes about 7%–25% by weight of modafinil particles having diameters greater than 220 μm and about 75%–93% by weight of modafinil particles having diameters less than 220 μm. | Inventors
AssigneeApplicationNo. 10616240 filed on 07/08/2003US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/464, Tablets, lozenges, or pills424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/452, With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.)424/457, Sustained or differential release514/618Sulfur in RField of Search424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/457, Sustained or differential release424/452, With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.)424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/464Tablets, lozenges, or pillsExaminersPrimary: Webman, Edward J.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 9/16A61K 9/26 A61K 9/48 |