Delivery of therapeutic capable agents

Patent 7083642 Issued on August 1, 2006. Estimated Expiration Date:

July 25, 2022. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3705894

3705946

3777020

3868454

3880995

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Inventors

Assignee

Avantec Vascular Corporation

Application

No. 10206853 filed on 07/25/2002

US Classes:

623/1.42, Drug delivery623/1.15, Stent structure623/3.1, CORPOREAL ARTIFICIAL HEART, HEART ASSIST (E.G., IMPLANTABLE BLOOD PUMP, ETC.), CONTROL REGULATOR, OR POWER SUPPLY THEREFOR, OR METHOD OF OPERATION THEREFOR604/265, With body soluble, antibactericidal or lubricating materials on conduit424/78.17, Aftertreated polymer (e.g., grafting, blocking, etc.)623/11.11, IMPLANTABLE PROSTHESIS623/1.45, Impregnation623/1.13Stent in combination with graft

Examiners

Primary: Barrett, Thomas
Assistant: Izquierdo, David A.

Attorney, Agent or Firm

Townsend and Townsend and Crew LLP

Foreign Patent References

063 365 EP 09/01/1985
184 162 EP 04/01/1994
0 923 953 EP 06/01/1999
0950386 EP 10/01/1999
1277449 EP 01/01/2003
WO 90/13332 WO 11/01/1990
WO 98/36784 WO 08/01/1998
WO 00/10622 WO 03/01/2000
WO 01/01957 WO 01/01/2001
WO 01/41678 WO 06/01/2001
WO 02/083039 WO 10/01/2002

International Class

A61F 2/06

Abstract

The present invention provides improved stents and other prostheses for delivering substances to vascular and other luminal and intracorporeal environments. In particular, the present invention provides for therapeutic capable agent eluting stents with minimized undesirable loss of the therapeutic capable agent during expansion of the stent.

Other References

Rajasubramanian et al., “Fabrication of resorbable microporus intravascular stents for gene therapy applications,” ASAIO Journal, 40:M584-589 (1994).
U.S. Appl. No. 09/782,927, filed Feb. 13, 2001, entitled “Intravascular delivery of mycophenolic acid.”
U.S. Appl. No. 09/783,254, filed Feb. 13, 2001, entitled Intravascular delivery of mizorbine.
U.S. Appl. No. 09/782,804, filed Feb. 13, 2001, entitled Intravascular delivery of methylprednisolone.
Mohacsi et al., “Different inhibitory effects of immunosuppresive drugs on hyman and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor” J Heart and Lung Transplant, 16:484-491 (1997).
Nghiem, et al.; “Tacrolimus and Pimecrolimus: From Clever Prokaryotes to Inhibiting Calcineurin and Treating Atopic Dermatitis;” J Am Acad Dermatol; Feb. 2002; pp. 228-241; vol. 46; No. 2; American Academy of Deratology, Inc.
Web page; “Ascomycin Macrolactams;” Ascomycin Macrolactams Fact Sheet; at URL=http://ascomycin.noneto.com/; printed Mar. 11, 2004; 2 pages.