Method for preparing 2- (2-pyridylmethylsulphinyl) benzimidazoles
Patent 7064213 Issued on June 20, 2006. Estimated Expiration Date: 
April 27, 2025. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 27, 2025. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPreparation of omeprazole and lansoprazole Patent #: 5374730 InventorAssigneeApplicationNo. 11115160 filed on 04/27/2005US Classes:546/272.7, 1,3-diazoles (including hydrogenated)546/273.7Chalcogen bonded directly to a ring carbon of the 1,3-diazole ringExaminersPrimary: Morris, Patricia L.Attorney, Agent or FirmForeign Patent References
International ClassC07D 401/12AbstractThe present invention provides a method for preparing an antiulcer agent, 2-(2-pyridylmethylsulphinyl)benzimidazoles, such as Omeprazole, Lansoprazole and Pantoprazole, which includes oxidizing an intermediate having a linkage of methylthio group (—CH2S—) to methylsulfinyl (—CH2S(O)—) in the presence of an oxidation catalyst of acetyl acetonate of molybdenium (II) [(CH3C(O)CH2C(O)CH2)2Mo].Other References
|
| ||||||||||||||
