Patent References 3894950 Automatic pipetting apparatus Test array for performing assays Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis Multi-well bioassay tray with evaporation protection and method of use Test sample card with polymethylpentene tape Apparatus for accessing a sealed container Universal washing apparatus for microtiter plate and the like Multi-well plate Self-resealing, puncturable container cap InventorsAssigneeApplicationNo. 09573998 filed on 05/19/2000US Classes:436/180, Volumetric liquid transfer436/174, INCLUDING SAMPLE PREPARATION436/177, Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.)436/179, Dilution422/99, Miscellaneous laboratory apparatus and elements, per se422/100, Pipette or other volumetric fluid transfer means422/102, Container210/131, By movement of separation medium73/864.21, With sample supply to analyzer436/530, Cellulose or derivative436/178, Including use of a solid sorbent, semipermeable membrane, or liquid extraction436/48, With step of insertion or removal from test line436/18, Preservative, buffer, anticoagulant or diluent134/21, Including use of vacuum, suction, or inert atmosphere435/288.4, Including multiple compartments (e.g., wells, etc.)422/65, Means is conveyor and rack422/130Bench scaleExaminersPrimary: Warden, JillAssistant: Handy, Dwayne K Attorney, Agent or FirmForeign Patent References
International ClassG01N001/10AbstractA multiwell plate for microarraying comprising a self-sealing lower membrane and optionally also a self-sealing upper membrane. Spotting is performed by pushing a pin down through the liquid and then on to pierce the self-sealing lower membrane. A slide having an upper spotting surface is arranged under the well plate. The liquid sample forced through the lower membrane by the pin tip can thus be deposited directly onto the spotting surface. The pin is then withdrawn upwards through the lower membrane, which automatically reseals preventing further loss of liquid. The optional resealable upper membrane also prevents loss of sample liquid by evaporation and spillage. By contrast to the prior art, there is the major advantage that the pin head does not have to traverse between the well plate and slide to collect sample liquid, thus dramatically increasing operational speed for an automated microarraying apparatus employing the multiwell plate. Excellent spot reproducibility is also observed.Field of SearchDilutionINCLUDING SAMPLE PREPARATION Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.) Including use of a solid sorbent, semipermeable membrane, or liquid extraction Volumetric liquid transfer Test package or kit In holder or container having special form Miscellaneous laboratory apparatus and elements, per se Pipette or other volumetric fluid transfer means Container Including means for separating a constituent; e.g., filter, condenser, extractor, etc. |
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