U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Meloxicam for oral administration

Patent 6869948 Issued on March 22, 2005. Estimated Expiration Date: Icon_subject March 26, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides and salts thereof
Patent #: 4233299
Issued on: 11/11/1980
Inventor: Trummlitz ,   et al.

Water soluble salts of an NSAID with meglumine/glucamine Patent #: 4748174
Issued on: 05/31/1988
Inventor: Veronesi

Inventors

Assignee

Application

No. 09277049 filed on 03/26/1999

US Classes:

514/226.5, One of the cyclos is a 1,2-thiazine (e.g.,1,2-benzothiazines, etc.)544/49Benzothiazines (including hydrogenated)

Examiners

Primary: Raymond, Richard L.
Assistant: Truong, Tamthom N.

Attorney, Agent or Firm

Foreign Patent References

  • 37 00 172 DE 07/01/1987
  • 0 002 482 EP 06/01/1979
  • WO 97 17978 WO 05/01/1997
  • WO 99 09988 WO 03/01/1999

International Classes

A61K031/54
C07D279/16

Abstract

The invention relates in its first aspect to a rapidly decomposing tablet for pain therapy containing meloxicam [4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide] in the form of a salt with an inorganic or organic base providing rapid absorption of the active substance, the process of its preparation by direct tabletting, and furthermore relates in a second aspect to the crystalline meloxicam meglumin salt mono- and dihydrate and the preparation thereof.

Other References

  • Luger et al; “Structure and physicochemical properties of meloxicam, a new NSAID”; European Journal of Pharmaceutical Sciences; Bd. 4, 1996, Seiten 175-187, XP002074736 *siehe Zusammenfassung; Seite 177, linke Spalte; und Seite 178 Tabelle 1*.
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