Chemokine receptor binding heterocyclic compounds

Patent 6864265 Issued on March 8, 2005. Estimated Expiration Date:

September 17, 2021. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Antiviral cyclic polyamines
Patent #: 5021409
Issued on: 06/04/1991
Inventor: Murrer, et al.

Aromatic-linked polyamine macrocyclic compounds with anti-HIV activity
Patent #: 5583131
Issued on: 12/10/1996
Inventor: Bridger, et al.

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Patent #: 5698546
Issued on: 12/16/1997
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Antiviral compounds
Patent #: 5817807
Issued on: 10/06/1998
Inventor: Bridger, et al.

Chemical compounds Patent #: 6001826
Issued on: 12/14/1999
Inventor: Murrer, et al.

Inventors

Assignee

AnorMED, Inc.

Application

No. 09957682 filed on 09/17/2001

US Classes:

514/314, Additional hetero ring attached directly or indirectly to the quinoline ring system by nonionic bonding514/311, Quinolines (including hydrogenated)514/313, Nitrogen, other than as nitro or nitroso, attached directly to the six membered hetero ring by nonionic bonding546/135, Additional hetero ring containing546/160, Unsaturated carbocyclic ring bonded directly to the nitrogen546/159Nitrogen, other than as nitro or nitroso, attached directly to the six membered hetero ring by nonionic bonding

Examiners

Primary: Desai, Rita

Attorney, Agent or Firm

Morrison & Foerster LLP

Foreign Patent References

1163238 EP 12/01/2001
WO 993851 WO 08/01/1999
WO 0042852 WO 07/01/2000
WO 0051607 WO 09/01/2000
WO 0056729 WO 09/01/2000
2000056729 WO 09/01/2000
2002022599 WO 03/01/2002
2002022600 WO 03/01/2002

International Classes

A61K031/4436
A61K031/4439
A61K031/4725
C07D471/00

Abstract

Compounds that bind to chemokine receptors such as CXCR4 and CCR5 demonstrate protective effects against infection of cells by human immunodeficiency virus are disclosed. These compounds contain a tertiary amine[[s]] linked to a core nitrogen via an aromatic or heteroaromatic moiety.

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