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...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!
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US Patent 6855721 - Methods and compositions for alleviating stuttering
US Patent Issued on February 15, 2005
Estimated Patent Expiration Date:
July 28, 2020Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
July 28, 2020Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractMethods of treating stuttering include treating people with gamma-aminobutyric acid (GABA) receptor modulators, including cyclopyrrolones. A second active agent may be used with GABA receptor modulators. Active enantiomers, active metabolites, and pharmaceutically acceptable salts of gamma-aminobutyric acid receptor modulators, including cyclopyrrolones, are acceptable components of the compositions. The cyclopyrrolone class of modulators includes pagoclone, suriclone, zopiclone, 2-(7-chloro-2-naphthyridin-1,8-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one, 2-(7-chloro-2-naphthyridin-1,8-yl)isoindolin-1-yl-4-acetamidobutyrate, and 2-(7-chloro-1,8-naphthyridin-2y1)-3-(5-methyl-5-hydroxy-2-oxohexyl)-1-isoindolinone.Other References
| InventorsAssigneeApplicationNo. 09628803 filed on 07/28/2000US Classes:514/300, Plural hetero atoms in the bicyclo ring system424/468, Sustained or differential release type424/419, Natural or synthetic resin424/488, Polysaccharides (e.g., cellulose, etc.)424/497, Containing solid synthetic polymers424/480, Cellulose or derivative546/122, The other cyclo in the bicyclo ring system is also six-membered (e.g., naphthyridines, etc.)210/198.2ChromatographyField of Search514/300, Plural hetero atoms in the bicyclo ring system514/310Nitrogen, other than as nitro or nitroso, attached directly to the isoquinoline ring system by nonionic bondingExaminersPrimary: Padmanabhan, SreeniAssistant: Hui, San-Ming Attorney, Agent or FirmUS Patent References4401663, Novel sulfonamide derivativesIssued on: 08/30/1983 Inventor: Buckwalter , et al.4788055, Resinate sustained release dextromethorphan composition Issued on: 11/29/1988 Inventor: Fischer , et al.4816264, Sustained release formulations Issued on: 03/28/1989 Inventor: Phillips , et al.4828836, Controlled release pharmaceutical composition Issued on: 05/09/1989 Inventor: Elger , et al.4834965, Controlled release pharmaceutical composition Issued on: 05/30/1989 Inventor: Martani , et al.4834985, Controlled release pharmaceutical composition Issued on: 05/30/1989 Inventor: Elger , et al.4960779, Pyrrole derivatives, and pharmaceutical compositions which contain them and pharmacological methods of use Issued on: 10/02/1990 Inventor: Bourzat, et al.4996047, Sustained release drug-resin complexes Issued on: 02/26/1991 Inventor: Kelleher, et al.5071646, Pharmaceutical ion exchange resin composition Issued on: 12/10/1991 Inventor: Malkowska, et al.5133974, Extended release pharmaceutical formulations Issued on: 07/28/1992 Inventor: Paradissis, et al.5494915, Isoindolinone derivative, preparation thereof, and pharmaceutical compositions containing same Issued on: 02/27/1996 Inventor: Barreau, et al.5599936, Isoindolinone derivative, preparation thereof and pharmaceutical compositions containing same Issued on: 02/04/1997 Inventor: Barreau, et al.5676831Isoindolinone derivative, preparation thereof and pharmaceutical compositions containing same Issued on: 10/14/1997 Inventor: Barreau, et al. Foreign Patent References
International ClassA61K031/44 |
