Recombinant protein production in a human cell
Patent 6855544 Issued on February 15, 2005. Estimated Expiration Date: 
April 14, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 14, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPackaging systems for human recombinant adenovirus to be used in gene therapy Recombinant DNA method and host cells Patent #: 6653101 Inventors
AssigneeApplicationNo. 09549463 filed on 04/14/2000US Classes:435/325, ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)435/455, Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell435/69.7, Fusion proteins or polypeptides536/23.1, DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)536/23.5, Encodes an animal polypeptide536/23.72, Viral protein536/24.1Non-coding sequences which control transcription or translation processes (e.g., promoters, operators, enhancers, ribosome binding sites, etc.)ExaminersPrimary: Wax, Robert A.Assistant: Mitra, Rita Attorney, Agent or FirmForeign Patent References
International ClassesC12N005/00C12N015/63 C12N021/04 C12P021/06 AbstractMethods and compositions for the production of recombinant proteins in a human cell line. The methods and positions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese Hamster Ovary cells.Other References
Field of SearchANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORERecombinant DNA technique included in method of making a protein or polypeptide VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.) Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell Blood proteins Fusion proteins or polypeptides Expressing recombinant hormone or growth factor Primate cell, per se COS (e.g., COS-7, etc.) Human HeLa cell or derivative Nervous system origin or derivative Renal origin or derivative Hepatic origin or derivative Epithelial origin or derivative Blood, lymphatic, or bone marrow origin or derivative Myeloma origin or derivative B-cell or derivative T-cell or derivative DNA or RNA fragments or modified forms thereof (e.g., genes, etc.) Encodes an animal polypeptide Viral protein Non-coding sequences which control transcription or translation processes (e.g., promoters, operators, enhancers, ribosome binding sites, etc.) |
| ||||||||||||||
