Store operated calcium influx inhibitors and methods of use
May 31, 2022. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesHypocholesteremic fermentation products and process of preparation ML-236B Derivatives and their preparation Antihypercholesterolemic compounds Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases Substituted hydroxylamines Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor compound Benzothiophene, benzofuran and indole compounds Method for the treatment of skin disorders using inhibitor of cholesterol synthesis Patent #: 6126947 InventorsApplicationNo. 10/160977 filed on 05/31/2002US Classes:514/340, Ring nitrogen in the additional hetero ring (e.g., oxazole, etc.)514/365, 1,3-thiazoles (including hydrogenated)514/374, 1,3-oxazoles (including hydrogenated)514/414, Additional hetero ring which is not part of the bicyclo ring system514/415, The bicyclo ring system consists of the five-membered hetero ring and a benzene ring (e.g., indole, etc.)546/277.4, Bicyclo ring system which is indole (including hydrogenated)548/202, Plural double bonds between ring members of thiazole ring548/235, Plural double bonds between the ring members of the oxazole ring548/466The additional hetero ring is bonded directly to a ring carbon of the bicyclo ring systemExaminersPrimary: Solola, TaofiqAttorney, Agent or FirmInternational ClassesA61K 31/00 (20060101)A61K 31/403 (20060101) A61K 31/435 (20060101) A61K 31/366 (20060101) A61K 31/405 (20060101) AbstractThe present invention provides store operated calcium influx inhibitor compounds, pharmaceutical compositions, and methods of use. The compounds are useful for treating an inflammatory disease or treating an inflammatory reaction. Preferably, compounds, compositions and methods of this invention are used for treatment of inflammatory skin, pulmonary, musculoskeletal, and gastrointestinal diseases, as well as autoimmune disorders, transplantation treatment, and osteoporosis.Other References
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