Method and compositions for regulation of 5-alpha reductase activity
Patent 6696484 Issued on February 24, 2004. Estimated Expiration Date: April 24, 2022. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/456, Bicyclo ring system having the hetero ring as one of the cyclos (e.g., chromones, etc.)514/337, The additional hetero ring is one of the cyclos in a polycyclo ring system514/453, Polycyclo ring system having the hetero ring as one of the cyclos514/455, Chalcogen bonded directly to ring carbon of the hetero ring514/457, Coumarins (including hydrogenated)514/532, Z-C(=O)-O-Y, wherein Z contains a benzene ring514/544, C(=O)O attached directly through the carbon to a benzene ring514/557, Carboxylic acid, percarboxylic acid, or salt thereof (e.g., peracetic acid, etc.)514/558, Higher fatty acid or salt thereof514/617, R contains benzene ring514/622, C-O- group in R514/646, Benzene ring containing514/655, The aryl ring or aryl ring system and amino nitrogen are bonded directly to the same acylic carbon, which carbon additionally has only hydrogen or acyclic hydrocarbyl substituents bonded directly thereto514/678, Benzene ring containing514/679, Plural rings514/680, Polycyclo ring system514/681, Bicyclo514/682, Naphthyl ring system514/683, Alicyclic ring514/720, Acyclic carbon to carbon unsaturation514/729, Alicyclic ring containing514/731, C of C-O- group is nuclear C of a benzene ring (e.g., phenol, phenolate, etc.)514/732Polycyclo ring system (e.g., naphthols, etc.)
Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5-reductase inhibitor, such as natural and synthetic flavanoids, catechols, curcumin-related substances, quinones, catechins, particularly epigallocatechin derivatives, fatty acids, and the salts, esters, analogues, pro-drugs, isomers, racemic mixtures, or derivatives of any of the foregoing. The use of testosterone (or DHT) combinations with the aforementioned 5-reductase inhibitor compounds is also contemplated.
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