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US Patent 6612988 - Ultrasound therapy

US Patent Issued on September 2, 2003
Estimated Patent Expiration Date: Icon_subject December 15, 2020Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

The invention provides a method of delivering ultrasound signals. The method includes providing an image of at least a portion of a subject intended to receive ultrasound signals between sources of the ultrasound signals and a desired region of the subject for receiving focused ultrasound signals, identifying, from the image, physical characteristics of different layers of material between the sources and the desired region, and determining at least one of phase corrections and amplitude corrections for the sources depending on respective thicknesses of portions of each of the layers disposed between each source and the desired region.

Other References

  • Notification of Transmittal of The International Search Report or the Declaration, mailed Jul. 15, 2002
  • Hynynen, et al., "Demonstration of Potential Noninvasive Ultrasound Brain Therapy Through an Intact Skull", Ultrasound in Medicine and Biology, vol. 24, No. 2, pp. 275-283, 1998
  • Sun, et al., "Focusing of Therapeutic Ultrasound Through A Human Skull: A Numerical Study", J. Acoust. Soc. Am. 104(3) pt. 1, pp. 1705-1715, Sep. 1998
  • Hynynen, Kullervo, "Trans-skull Ultrasound Therapy: The Feasibility of Using Image-Derived Skull Thickness Information to Correct the Phase Distortion", IEEE Trans. on Ultrasonics, Ferroelectrics, and Freq. Control, pp. 752-755, vol. 46, No. 3, May 1999
  • Sun, et al., "The Potential of Transskull Ultrasound Therapy and Surgery Using the Maximum Available Skull Surface Area", J. Acoust. Soc. Am. 105(4), pp. 2519-2527, Apr. 1999

Inventors

Assignee

Application

No. 09/738514 filed on 12/15/2000

US Classes:

600/439, With therapeutic device600/437, Ultrasonic600/443Anatomic image produced by reflective scanning

Field of Search

600/443, Anatomic image produced by reflective scanning600/447, Electronic array scanning600/437, Ultrasonic600/439, With therapeutic device600/445, Mechanical scanning600/448, Through-transmission (e.g., time-of-flight) imaging600/459, Structure of transducer or probe assembly600/456, With volumetric measurement600/458, Contrast enhancement600/432Piston-type ram forces material into body

Examiners

Primary: Jaworski, Francis J.
Assistant: Patel, Maulin

Attorney, Agent or Firm

US Patent References

4817614, Method and apparatus for adaptive focusing in a medical ultrasound imaging apparatus
Issued on: 04/04/1989
Inventor: Hassler ,   et al.
5052394, Method and apparatus for ultrasonic beam compensation
Issued on: 10/01/1991
Inventor: Carpenter, et al.
5113866, Method for ultrasound imaging
Issued on: 05/19/1992
Inventor: Hassler, et al.
5381792, Shock wave curing apparatus capable of correcting phase shifts contained in echo signals
Issued on: 01/17/1995
Inventor: Yanagida, et al.
5487306, Phase aberration correction in phased-array imaging systems
Issued on: 01/30/1996
Inventor: Fortes
5531117, Closed loop maximum likelihood phase aberration correction in phased-array imaging systems
Issued on: 07/02/1996
Inventor: Fortes
5590657, Phased array ultrasound system and method for cardiac ablation
Issued on: 01/07/1997
Inventor: Cain, et al.
5605154, Two-dimensional phase correction using a deformable ultrasonic transducer array
Issued on: 02/25/1997
Inventor: Ries, et al.
5752515, Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier
Issued on: 05/19/1998
Inventor: Jolesz, et al.
6013032, Beamforming methods and apparatus for three-dimensional ultrasound imaging using two-dimensional transducer array
Issued on: 01/11/2000
Inventor: Savord
6193663, Diagnostic ultrasound imaging method and system with improved frame rate
Issued on: 02/27/2001
Inventor: Napolitano, et al.
6419633, 2D ultrasonic transducer array for two dimensional and three dimensional imaging
Issued on: 07/16/2002
Inventor: Robinson, et al.
6425867Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy
Issued on: 07/30/2002
Inventor: Vaezy, et al.

International Classes

A61N 7/00 (20060101)
A61N 7/02 (20060101)
A61B 19/00 (20060101)

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