Patent 6605644 Issued on August 12, 2003. Estimated Expiration Date: October 26, 2021. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
A regimen for the administration of tramadol for the treatment of analgesia is described. The regimen involves a slower initial titration rate of tramadol which results in a significantly lower percentage of discontinuations of therapy due to a lower incidence and severity of side effects.
Other References
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Barkin et al.: "Alternative dosing for tramadol aids effectiveness" Formulary, vol. 30, No. 9, 1995, pp. 542-543, XP000874395 the whole document
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October 26, 2021. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
