U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Systems and methods for detection of labeled materials

Patent 6597000 Issued on July 22, 2003. Estimated Expiration Date: Icon_subject July 8, 2022. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3216313

3385160

3632212

3798449

3802966

Linear scan system
Patent #: 3984171
Issued on: 10/05/1976
Inventor: Hotchkiss

Grinding method
Patent #: 4016855
Issued on: 04/12/1977
Inventor: Mimata

Rapid scan spectrophotometer
Patent #: 4070111
Issued on: 01/24/1978
Inventor: Harrick

Laser scanner for photolithography of slotted mask color cathode ray tubes
Patent #: 4176925
Issued on: 12/04/1979
Inventor: Kocher ,   et al.

Thermostatable flow cell for fluorescence measurements
Patent #: 4180739
Issued on: 12/25/1979
Inventor: Abu-Shumays

More ...

Inventor

Application

No. 191420 filed on 07/08/2002

US Classes:

250/458.1, LUMINOPHOR IRRADIATION250/461.2Biological cell identification

Examiners

Primary: Gagliardi, Albert

Attorney, Agent or Firm

Foreign Patent References

  • 194 132 EP. 09/13/1986
  • 271 974 EP. 06/13/1988
  • 304 202 EP. 02/13/1989
  • 3-6444 JP. 01/13/1991
  • WO 84/01031 WO. 03/13/1984
  • WO 90/15070 WO. 12/13/1990
  • WO 92/10092 WO. 06/13/1992
  • WO 93/02992 WO. 02/13/1993
  • WO 93/09668 WO. 05/13/1993
  • WO 95/11995 WO. 05/13/1995

International Classes

G01N 021/64
G01J 003/30

Abstract

Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by exposing marked regions of sample to radiation from a source and detecting the emission therefrom, and repeating the steps of exposition and detection until the sample is completely examined.

Other References

  • Chee et al., "Accessing Genetic Information with High-Density DNA Arrays," Science, vol. 274, pp. 610-614 (Oct. 25, 1996)
  • Lockhart et al., "Expression monitoring by hybridization to high-density oligonucleotide arrays," Nature Biotechnology, vol. 14, No. 13, pp. 1675-1680 (Dec. 1996)
  • Sapolsky et al., "Mapping Genomic Library Clones Using Oligonucleotide Arrays," Genomics, vol. 33, Article No. 0219, pp. 445-456 (1996)
  • Dixon et al., "Confocal scanning beam laser microscope/macroscope: Applications in Fluorescence," Progess in Biomedical Optics, SPIE, Proceedings of Fluorescence Detection IV, vol. 2705, pp. 44-52 (1996)
  • Alexay et al., "Fluorescence scanner employing a Macro Scanning Objective," Progress in Biomedical Optics, SPIE, Proceedings of fluorescence Detection IV, vol. 2705, pp. 63-72 (1996)
  • Pease at al., "Light-generated oligonucleotide arrays for rapid DNA sequence analysis," Proc. Natl. Acad. Sci. USA, vol. 91, pp. 5022-5026 (May 1994)
  • Yamamoto et al., "Features and applications of the laser scanning microscope," Journal of Modern Optics, vol. 37, No. 11, pp. 1691-1701 (1990)
  • Ekins et al., "Multianalyte microspot immunoassay--microanalytical `compact disk` of the future," Clin. Chem., vol. 37, No. 11, pp. 1955-1967 (Nov. 1991)
  • Benschop et al., "Confocal compact scanning optical microscope based on compact disk technology," Chemical Abstracts, vol. 114, No. 26, p. 114:256643p. (Jul. 1, 1991)
  • Fodor et al., "Light-Directed, Spatially Addressable Parallel Chemical Synthesis," Science, vol. 251, pp. 767-773 (Feb. 15, 1991)
  • Quesada et al., "High-Sensitivity DNA Detection with a Laser-Excited Confocal Fluorescence Gel Scanner," BioTechniques, vol. 10, No. 5, pp. 616-625 (1991)
  • Yamamoto et al., Features and applications of the laser scanning microscope, Journal of Modern Optics, vol. 37, No. 11, pp. 1691-1701 (1990)
  • Ekins et al., "Development of microspot multianalyte ratiometric immunoassay using dual fluorescent-labelled antibodies," Analytica Chimica ACTA, vol. 227, pp. 73-96 (Dec. 1, 1989)
  • White et al., "An Evaluation of Confocal Versus Convention Imaging of Biological Structures by Fluorescence Light Microscopy," The Journal of Cell Biology, vol. 105, No. 1 (Jul. 1987)
  • Van der voort et al., "Design and Use of a Computer Controlled Confocal Microscope for Biological Applications," Scanning, vol. 7, No. 2, pp. 66-78 (1985
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?