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Method and an apparatus for stimulating/ modulating biochemical processes using pulsed electromagnetic fields

Patent 6561968 Issued on May 13, 2003. Estimated Expiration Date: Icon_subject August 29, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

882699

3915151

Apparatus for maintaining the negative potential of human, animal, and plant cells
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Inventor: Fragnet

Electromagnetic apparatus and method for the reduction of serum glucose levels
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Use of ferromagnetic, paramagnetic and diamagnetic particles in the treatment of infectious diseases
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Electronic system for the activation, inhibition and/or modification of the development and functioning of cells, organs and organisms of living beings
Patent #: 4641633
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Inventor: Delgado

Method and apparatus for treatment of biological tissue
Patent #: 4672951
Issued on: 06/16/1987
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Horticultural device for raising garden plants utilizing magnetism
Patent #: 4785575
Issued on: 11/22/1988
Inventor: Shioi

More ...

Inventors

Assignee

Application

No. 650044 filed on 08/29/2000

US Classes:

600/13Electromagnetic coil

Examiners

Primary: Hindenburg, Max
Assistant: Cadugan, Joseph A.

Attorney, Agent or Firm

Foreign Patent References

  • 3403786 A 1 DE. 08/13/1985
  • 0 709 115 EP. 05/13/1996
  • 0788813 EP. 08/13/1997
  • 0 940 157 EP. 09/13/1999
  • WO 85/00293 WO. 01/13/1985
  • WO 97/40887 WO. 11/13/1997
  • WO 99/10041 WO. 03/13/1999

International Class

A61N 002/02

Foreign Application Priority Data

1999-08-31 DK

Abstract

A method for stimulating growth in biological tissue or sprouts, an apparatus and a use thereof employs fluctuating magnetic fields. The apparatus includes a pulse generator and a plurality of coils in which pulsed currents will cause fluctuating magnetic fields in a predetermined region holding the material to be stimulated. The fluctuating magnetic fields will induce an electric field in the material. An enhanced effect has been detected in the regions where the electric fields are largest. The coils include a number of pairs of coils having, during a given pulse, magnetic fields in opposite directions in order to provide field gradients in the cells, micro organisms or tissue. Selecting a suitable number, size and positioning of coils will provide a homogeneous electric field in the predetermined region, which does not have any undesirable peaked maxima. When four or more coils are used, they can be combined in pairs arranged on opposite sides of the predetermined region, and with the adjacent coils conducting current in opposite directions and the opposing coils conducting currents in the same direction. Thereby, the induced electrical fields add constructively inside the regions between the pairs of coils. In an apparatus for stimulating cell proliferation and differentiation, it is a desired feature that the generated fluctuations in the magnetic fields do not elicit action potentials of living cells since this will cause great inconvenience for the patient.

Other References

  • Article: Trock, David H. et al., "The Effect of Pulsed Electromagnetic Fields in the Treatment of Osteoarthritis of the Knee and Cervical Spine. Report of Randomized, Double Blind, Placebo Controlled Trials", pp. 1903-1911, The Journal of Rheumatology, 1994; 21-10
  • Article: Patino, Osvaldo et al., "Pulsed Electromagnetic Fields in Experimental Cutaneous Wound Healing in Rats", pp. 528-531, Journal of Burn Care & Rehabiliation, vol. 17, No. 6, Part 1, Mar. 1996
  • Article: Portier, Christopher, and Wolfe, Mary S. (editors), Assessment of Health Effects from Exposure to Power-Line Frequency Electric and Magnectic Fields, pp. 256-257, NIH Publication No. 98-3981, Aug. 1998
  • Article: Bassett, C.A.L. et al., "A Non-Operative Salvage of Surgically-Resistant Pseudarthroses and Non-Unions by Pulsing Electromagnetic Fields", pp. 128-142, Clinical Orthopaedics and Related Research, No. 124, May 1977
  • Article: Sisken, B.F. et al., "Stimulation of rat sciatic nerve regeneration with pulsed electromagnectic fields", pp309-316, Brain Research, 485, (1989)
  • Article: Bassett, C.A.L. et al., "Treatment of Ununited Tibial Diaphyseal Fractures with Pulsing Electromagnetic Fields",pp. 511-523, The Journal of Bone and Joint Surgery, vol. 63-A, No. 4, Apr. 198
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