Calibration methods and systems for diffuse optical tomography and spectroscopy
Patent 6549284 Issued on April 15, 2003. Estimated Expiration Date: 
September 15, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 15, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesCalibrated spectrographic imaging Method for measuring internal information in scattering medium and apparatus for the same Method and system for imaging objects in turbid media using diffusive fermat photons Self referencing photosensor Patent #: 6078833 InventorsAssigneeApplicationNo. 662862 filed on 09/15/2000US Classes:356/446With diffusionExaminersPrimary: Stafira, Michael P.Attorney, Agent or FirmInternational ClassG01N 021/47AbstractThe invention features a calibration method for diffuse optical measurements that corrects transmittance measurements between a source and a detector for factors unrelated to sample properties. The calibration method is based on the same set of transmittance measurements that are subsequently corrected by the calibration and used in imaging and/or spectroscopy applications. The calibration method involves a forward calculation for each of multiple source-detector pairs based on an approximate model of the sample, and a minimization of an expression that depends on the forward calculations and the transmittance measurements to determine self-consistent coupling coefficients for every source-detector pair. Once the coupling coefficients have been determined, they can be used to correct the transmittance measurements. If desired, an inverse calculation can be performed on the corrected sample measurements to determine spatial variations in the optical properties of the sample. If necessary, the calibration can be repeated and iteratively improved, whereby the optical properties determined by the inverse calculation in an earlier iteration are used to improve the sample model for the forward calculation in a subsequent iteration.Other References
Field of SearchOF LIGHT REFLECTION (E.G., GLASS)With diffusion By comparison BY DISPERSED LIGHT SPECTROSCOPY For spectrographic (i.e., photographic) investigation With spectral analysis With internal standard comparison Infrared responsive Methods METHODS OF DETERMINING OIL PRESENCE, CONTAMINATION OR CONCENTRATION | |
