U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Synthetic biological membrane with self organizing properties

Patent 6537575 Issued on March 25, 2003. Estimated Expiration Date: Icon_subject July 28, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Gel-forming liquid carrier composition Patent #: 5492937
Issued on: 02/20/1996
Inventor: Bogentoft, et al.

Inventors

Assignee

Application

No. 627808 filed on 07/28/2000

US Classes:

424/484, Matrices424/78.17, Aftertreated polymer (e.g., grafting, blocking, etc.)424/450, Liposomes424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)514/772.1Aftertreated solid synthetic organic polymer (e.g., grafting, blocking, etc.)

Examiners

Primary: Page, Thurman K.
Assistant: Fubara, Blessing

Attorney, Agent or Firm

International Classes

A61K 009/14
A61K 031/74
A61K 009/127
A61K 047/30

Abstract

A mixture is provided which manifests a gel phase at a temperature higher than that in which the mixture manifests a liquid phase. The mixture is a combination of a lipid, a polymer-grafted phospholipid and a surfactant. It is biomimetic in nature and changes phases when subjected to one or a plurality of environmental stimuli.

Other References

  • Firestone et al., "Structure and Optical Properties of a Thermoresponsive Polymer-Grafted, Lipid Based Complex Fluid" Langmuir, vol. 14, No. 17, p 5688-4698.
  • Firestone, Millicent, et al., Magnetic Field-Induced Ordering of a Polymer-Grafted Biomembrane--Mimetic Hydrogel, The Journal of Physical Chemistry, Mar. 23, 2000, pp. 2433-2438, vol. 104, No. 11, American Chemical Society, U.S
  • Firestone, Millicent, et al., Structure and Optical Properties of a Thermoresponsive Polymer-Grafted, Lipid Based Complex Fluid Langmuir, vol. 14, No. 17, pp. 4688-469
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