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Prevention and treatment of retinal ischemia and edema

Patent 6524581 Issued on February 25, 2003. Estimated Expiration Date: Icon_subject December 29, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Blocking cell adhesion molecules and treating animals with ocular inflammation
Patent #: 5597567
Issued on: 01/28/1997
Inventor: Whitcup, et al.

Delivery construct for antisense nucleic acids and methods of use
Patent #: 5814500
Issued on: 09/29/1998
Inventor: Dietz

Antibodies to sICAM-1
Patent #: 5821341
Issued on: 10/13/1998
Inventor: McClelland, et al.

Human 댢 integrin ଱ subunit Patent #: 5831029
Issued on: 11/03/1998
Inventor: Gallatin, et al.

Inventor

Assignee

Application

No. 474523 filed on 12/29/1999

US Classes:

424/130.1, IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL530/387.1Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed

Examiners

Primary: Wang, Andrew
Assistant: Schultz, James

Attorney, Agent or Firm

Foreign Patent References

  • 0 314 863 EP. 05/12/1989
  • 0 512 301 EP. 11/12/1992
  • 0 528 931 EP. 07/12/1998
  • WO 91/16927 WO. 11/12/1991
  • WO 93/06864 WO. 04/12/1993
  • WO 98/24797 WO. 06/12/1998
  • WO 98/46264 WO. 10/12/1998
  • WO 99/45920 WO. 09/12/1999

International Classes

A61K 039/395
C07K 016/00

Abstract

The present invention relates to methods of treating retinopathy, retinal ischemia and/or retinal edema comprising administering an integrin or integrin subunit antagonist, leukocyte adhesion-inducing cytokine antagonist or growth factor antagonist, a selectin antagonist or adhesion molecule antagonist.

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