U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Precipitation process of 7-aminocephalosporanic acid (7-ACA)

Patent 6518420 Issued on February 11, 2003. Estimated Expiration Date: Icon_subject November 7, 2021. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3367933

3507860

3507862

3575970

3594370

3594371

3813389

3840532

Process for the manufacture of aminoazetidinones
Patent #: 3957771
Issued on: 05/18/1976
Inventor: Bormann ,   et al.

Cephalosporin purification process
Patent #: 4028355
Issued on: 06/07/1977
Inventor: Blackburn

More ...

Inventors

Assignee

Application

No. 035638 filed on 11/07/2001

US Classes:

540/2197-amino cephalosporanic acid per se or salt thereof (i.e., 7-ACA or salt thereof)

Examiners

Primary: Berch, Mark L.

Attorney, Agent or Firm

Foreign Patent References

  • 15 45 898 DE. 04/25/1970
  • 22 22 094 DE. 11/25/1973
  • 25 02 197 DE. 07/25/1975
  • 30 02 659 DE. 07/25/1980
  • 1 277 228 GB. 06/25/1972
  • 1 421 199 GB. 01/25/1976

International Class

C07D 501/26

Foreign Application Priority Data

1997-06-04 AT

Abstract

A process in the isolation of 7-aminocephalosporanic acid (7-ACA) from an alkaline, neutral or slightly acidic medium in the presence of an additive, e.g. selected from the group comprising organic carboxylic acid esters, polymeric glycols, polyacryls, amines and polyamines, melaminformaldehyde resins or amino acids and esters thereof to obtain 7-ACA agglomerates and or rosettes.

Other References

  • European Phamacopoeia, Third Edition, p. 18, 1997.
  • Academnic Press Dictionary of Science and Technology, Morris, ed, (Academic Press, 1991) pp. 1688, 1690.
  • Hawley's Condensed Chemical Dictionary, 12th Edition (Van Nostrand Reinhold, 1993), p. 53.
  • Webster's Third New International Dictionary (Merriam Webster, Inc, 1986) p. 815.
  • Cieslak, Chemical Abstracts, vol. 90, No. 15, Abstract No. 121587p, p. 646, 1988
  • Derwent Abstract AN 93-098389 (RO 102 148 A) (1991)
  • Derwent Abstract AN 94-200170 (WO 94 12504 A and WO 94 12501 A) (1994)
  • Oberhauser, T. et al., Tetrahedron, vol. 52, No. 22, "On the Stereochemical Purity of (+)-7-Aminocephalosporanic Acid," pp. 7691-7702 (1996
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