Patent ReferencesSystemic delivery of polypeptides through the eye Patent #: 5182258 InventorsApplicationNo. 548759 filed on 04/13/2000US Classes:514/2, Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI530/300PEPTIDES OF 3 TO 100 AMINO ACID RESIDUESExaminersPrimary: Park, Hankyel T.Attorney, Agent or FirmForeign Patent References
International ClassesA01N 037/18A61K 038/00 AbstractThe present invention provides a highly dispersible formulation comprising an active agent and a dipeptide or tripeptide comprising at least two leucyl residues. The composition of the invention possesses superior aerosol properties and is thus preferred for aerosolized administration to the lung. Also provided are a method for (i) increasing the dispersibility of an active-agent containing formulation for administration to the lung, and (ii) delivery of the composition to the lungs of a subject. |
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