U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Progestogen-anti-progestogen regimens

Patent 6506390 Issued on January 14, 2003. Estimated Expiration Date: Icon_subject January 8, 2021. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Antiprogestin cyclophasic hormonal regimen
Patent #: 5521166
Issued on: 05/28/1996
Inventor: Grubb

Preparation for substitution therapy, containing at least one progestogen and at least one estrogen Patent #: 5827843
Issued on: 10/27/1998
Inventor: Koninckx

Inventors

Assignee

Application

No. 757048 filed on 01/08/2001

US Classes:

424/400, PREPARATIONS CHARACTERIZED BY SPECIAL PHYSICAL FORM424/423, Surgical implant or material424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/456, Gelatin424/464, Tablets, lozenges, or pills424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)514/169, Cyclopentanohydrophenanthrene ring system DOAI514/170Plural Compounds containing cyclopentanohydrophenanthrene ring systems

Examiners

Primary: Page, Thurman K.
Assistant: Channavajjala, Lakshmi

Attorney, Agent or Firm

Foreign Patent References

  • 43 44 463 DE. 03/13/1995
  • WO 93 21927 WO. 11/13/1993
  • WO 94 04156 WO. 03/13/1994
  • WO 96 15794 WO. 05/13/1996

International Class

A61K 009/00

Foreign Application Priority Data

1996-06-25 EP

Abstract

A contraceptive and/or HRT (hormone replacement therapy) kit comprising sequential daily dosage units each containing as the sole contraceptively effective ingredient a progestogen, or as the effective ingredient for HRT a progestogen with or without an estrogen or an estrogen only, and further two or more dosage units comprising an anti-progestogen. The present invention also provides contraceptive and HRT methods comprising administering daily dosage units of a progestogen and anti-progestogen.

Other References

  • Kekkomen et al., Fertility and Sterility 1990, vol. 53, p. 747-750
  • Kekkomen et al., Fertility and Sterility 1993, vol. 60, p. 610-615
  • The Physicians' Desk Reference, 52nd Edition, p. 306, 326-327 (Medical Economics Company 1998)
  • Ghosh et al., "Luteal phase contraception with mifepristone (RU486) in the rhesus monkey" Indian J. Physiol Pharmacol. vol. 1 p. 17-22 (Jan. 1994)
  • Katkam et al., "Onapristone (ZK 98.299): a potential antiprogestin for endometrial contraception" Am J. Obstet Gynecol. vol. 173 p. 779-787 (Sep. 1995
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