U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Complementing cell lines

Patent 6492169 Issued on December 10, 2002. Estimated Expiration Date: Icon_subject November 15, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for the production of non-group C adenoviral vectors
Patent #: 5849561
Issued on: 12/15/1998
Inventor: Falck-Pedersen

Packaging systems for human recombinant adenovirus to be used in gene therapy
Patent #: 5994128
Issued on: 11/30/1999
Inventor: Fallaux, et al.

Packaging systems for human recombinant adenovirus to be used in gene therapy
Patent #: 6033908
Issued on: 03/07/2000
Inventor: Bout, et al.

Packaging systems for human recombinant adenovirus to be used in gene therapy Patent #: 6306652
Issued on: 10/23/2001
Inventor: Fallaux, et al.

Inventors

Application

No. 713678 filed on 11/15/2000

US Classes:

435/325, ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/235.1, VIRUS OR BACTERIOPHAGE, EXCEPT FOR VIRAL VECTOR OR BACTERIOPHAGE VECTOR; COMPOSITION THEREOF; PREPARATION OR PURIFICATION THEREOF; PRODUCTION OF VIRAL SUBUNITS; MEDIA FOR PROPAGATING435/455Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cell

Examiners

Primary: Housel, James C.
Assistant: Foley, Shawn P.

Attorney, Agent or Firm

International Classes

C12N 005/02
C12N 007/00
C12N 015/63

Abstract

A packaging cell line capable of complemention recombinant adenoviruses based on serotypes from subgroup B, preferably adenovirus type 35. The cell line is preferably human embryonic kidney cells and primary human amniocytes) which are transformed by adenovirus E1 sequences either operatively linked on one DNA molecule or located on two separate DNA molecules, the sequences being operatively linked to regulatory sequences enabling transcription and translation of encoded proteins.

Other References

  • Abrahamsen et al. Journal of Virology. 1997; 71 (11): 8946-895
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