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Method for correcting the vigilance disorders associated with myopathies

Patent 6462089 Issued on October 8, 2002. Estimated Expiration Date: Icon_subject June 29, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Acetamide derivative having defined particle size Patent #: 5618845
Issued on: 04/08/1997
Inventor: Grebow, et al.

Inventors

Assignee

Application

No. 606238 filed on 06/29/2000

US Classes:

514/618, Sulfur in R514/923SLEEP AID (INSOMNIA)

Examiners

Primary: Krass, Frederick

Attorney, Agent or Firm

Foreign Patent References

  • 0 233 106 EP. 08/23/1987
  • 2 385 693 FR. 10/23/1978

International Class

A61K 031/165

Foreign Application Priority Data

2000-01-31 FR

Abstract

The present invention relates to the use of modafinil and isomers thereof for correcting psychosocial life disturbances due to vigilance disorders observed during the evolution of myopathies.

Other References

  • Chemical Abstract 126:258987, "Selegiline in the treatment of hypersomnolence in mytotonic dystrophy: a pilot study" (1997).
  • Marchand, F. et al, "Therapeutic results of modafinil in 32 patients out of 112 hypersomniacs examined in a sleep unit", Neurophysiol. Clin., vol. 21, No. 3, 1991, p. 227
  • Petiau, C. et al, "Somnolence diurne pathologique", Revue de Medecine Interne, vol. 18, No. 3, 1997, pp. 210-218
  • Bastuji, H. et al, "Successful Treatment of Idiopathic hypersomnia and narcolepsy with modafinil", Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 12, No. 5, 1988, pp. 695-700
  • Rochegude, S. et al, "Le modafinil: Modiodal.RTM.". Lyon Pharmaceutique, vol. 27, No. 7, 1996, pp. 363-366
  • Schwartz, J. et al, "Modafinil for the Treatment of Excessive Daytime Sleepiness Associated with Narcolepsy", Today's Therapeutic Trends, vol. 16, No. 4, 1998, pp. 287-308
  • Beusterien, K. et al, "Health-Related Quality of Life Effects of Modafinil for Treatment of Narcolepsy", Sleep, vol. 22, No. 6, Sep. 15, 1999, pp. 757-765
  • Billiard, M. et al, "Modafinil: A Double-Blind Multicentric Study", Sleep, vol. 17, No. Suppl. 8, 1994, pp. S107-S112
  • Billiard, M., "Narcolepsie", Revue du Praticien, vol. 46, No. 20, Dec. 15, 1996, pp. 2428-2434
  • Arnulf, I. et al, "Modafinil in Obstructive Sleep Apnea-Hypopnea Syndrome: A Pilot Study in 6 Patients", Respiration, vol. 64, No. 2, 1997, pp. 159-16
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