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US Patent 6451289 - Albuterol formulations

US Patent Issued on September 17, 2002
Estimated Patent Expiration Date: Icon_subject March 22, 2021Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

Albuterol formulations packaged in an oxygen-permeable plastic container have a long shelf life at room temperature. The formulations consist essentially of albuterol or a pharmaceutically acceptable salt thereof, sodium chloride, and water, have a pH of about 4, and contain less than 0.08% by weight of albuterol aldehyde and less than 1 ppm dissolved oxygen.

Other References

  • Schering, Drug Information on Proventil.RTM., revised Aug. 1999 (obtained through on-line PDR

Inventors

Assignee

Application

No. 815150 filed on 03/22/2001

US Classes:

424/45, Organic pressurized fluid206/204, WITH MOISTURE ABSORBENT424/401, Cosmetic, antiperspirant, dentifrice514/653, Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)560/42Oxy in acid moiety

Field of Search

424/45, Organic pressurized fluid424/401, Cosmetic, antiperspirant, dentifrice560/42, Oxy in acid moiety206/204, WITH MOISTURE ABSORBENT514/653Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)

Examiners

Primary: Dees, Jose G.
Assistant: Haghighatian, M.

Attorney, Agent or Firm

US Patent References

4206758, Device for dispensing medicaments
Issued on: 06/10/1980
Inventor: Hallworth ,   et al.
4353365, Device for dispensing medicaments
Issued on: 10/12/1982
Inventor: Hallworth ,   et al.
4499108, Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
Issued on: 02/12/1985
Inventor: Sequeira ,   et al.
4751071, Composition comprising salbutamol
Issued on: 06/14/1988
Inventor: Magruder ,   et al.
4777049, Constant release system with pulsed release
Issued on: 10/11/1988
Inventor: Magruder ,   et al.
4851229, Composition comprising a therapeutic agent and a modulating agent
Issued on: 07/25/1989
Inventor: Magruder ,   et al.
5362755, Method for treating asthma using optically pure (R)-albuterol
Issued on: 11/08/1994
Inventor: Barberich, et al.
5545745, Enantioselective preparation of optically pure albuterol
Issued on: 08/13/1996
Inventor: Gao, et al.
6113927, Package and packaging method for aqueous liquid materials
Issued on: 09/05/2000
Inventor: Hatakeyama
6119853Method and package for storing a pressurized container containing a drug
Issued on: 09/19/2000
Inventor: Garrill, et al.

International Classes

A61K 009/12
A61K 031/135

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