Gastroresistant multi-unitary pharmaceutical preparations containing piroxicam
Patent 6391341 Issued on May 21, 2002. Estimated Expiration Date: 
May 30, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 30, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDrug delivery system Pharmaceutical multiple unit particulate formulation in the form of coated cores Patent #: 5958458 InventorsApplicationNo. 580552 filed on 05/30/2000US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/400, PREPARATIONS CHARACTERIZED BY SPECIAL PHYSICAL FORM424/439, Food or edible as carrier for pharmaceutical424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/464, Tablets, lozenges, or pills424/468, Sustained or differential release type424/472, Layered unitary dosage forms424/490, Coated (e.g., microcapsules)514/951, POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE514/964, SUSTAINED OR DIFFERENTIAL RELEASE TYPE514/965Discrete particles in supporting matrixExaminersPrimary: Page, Thurman K.Assistant: Evans, Charesse Attorney, Agent or FirmInternational ClassesA61K 009/14A61K 009/16 A61K 009/50 Foreign Application Priority Data1999-12-16 EPAbstractThe present invention relates to multi-unitary pharmaceutical preparations containing piroxicam for oral administration. Such pharmaceutical preparations are stable pellet pharmaceutical preparations containing piroxicam and they comprise an amount of active ingredient of between 5 and 50 mg, an inert core with spherical symmetry and a diameter of 600-850 μm, constituted by inert excipients, coated with an active layer containing piroxicam in micronized form and various pharmaceutically acceptable inert excipients, mixed in appropriate proportions in order to allow the adequate disaggregation of the formulations and dissolution of the active ingredient, coated in it turn with an insulating layer of a polymeric nature and soluble in water, this layer being coated finally with a gastroresistant or enteric layer of a minimum thickness of 20 μm. This invention also refers to the process for the preparation of said pharmaceutical preparations.Field of SearchPREPARATIONS CHARACTERIZED BY SPECIAL PHYSICAL FORMFood or edible as carrier for pharmaceutical Tablets, lozenges, or pills Coated pills or tablets Particulate form (e.g., powders, granules, beads, microcapsules, and pellets) Coated (e.g., microcapsules) Containing solid synthetic polymers ARTHRITIS INFLAMMATION, SKIN POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.) SUSTAINED OR DIFFERENTIAL RELEASE TYPE Discrete particles in supporting matrix | |
