Patent 6383513 Issued on May 7, 2002. Estimated Expiration Date: June 16, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
There is provided a composition for the nasal delivery of a cannabinoid which comprises a cannabinoid in a biphasic delivery system or a cannabinoid in a microsphere delivery system.
Other References
IDSON, Pharmaceutical Emulsions, in Pharmaceutical Dosage Forms: Disperse Systems, vol. 1, Marcel Dekker, Inc., New York, USA, pp. 199-243 (1988)
WADE, et al. Eds., Handbook of Pharmaceutical Excipients, 2d. Ed., American Pharmaceutical Assoc., Washington D.C., USA, pp. 352-354 (1994)
GURNY et al. Eds., Bioadhesion -Possibilities and Future Trends, Wissensschaftliche Verlagsgessellschant mbH, Stuttgart, Germany (1990)
LENAERTS et al. Eds., Bioadhesive Drug Delivery Systems (Too voluminous to include complete text) CRC Press, Inc., Boca Raton, Florida, USA (1990)
BARNES, Therapeutic Uses of Cannabinoids, The Pharmaceutical Journal, p. 104 (1997)
LITZINGER et al., Effect of Liposome Size on the Circulation Time and Intraorgan Distribution of Amphipathic Poly(ethylene glucol)-Containing Liposomes, Biochemica et Biophysica Acta 1190, pp. 99-107 (1994)
MARTYN et al. Nabilone in the Treatment of Multiple Sclerosis, The Lancet, vol. 345, p. 579 (1995)
BEAL et al., Dronabinol as a Treatment of Anorexia Associated with Weight Loss in Patients with Aids, Journal of Pain and Symptom Management, vol. 10, No. 2, pp. 89-97 (1995)
BURSTEIN et al., Synthetic Nonpsychotropic Cannabinoids with Potent Antiinflammatory, Analgesic, and Leukocyte Antiadhesion Activities, J. Med Chem., vol. 35, pp. 3135-3141 (1992)
THOMPSON, Cyclodextrins-Enabling Excipients: Their Present and Future Use in Pharmaceuticals, Critical Reviews™ in Therapeutic Drug Carrier Systems, vol. 14, No. 1, pp. 1-104 (1997)
The United States Pharmacopedia: The National Formulary, United States Pharmacopedia Convention, Rockville, MD, USA (1995) (Too voluminous to include entire book