Sustained release polymer blend for pharmaceutical applications
Patent 6358525 Issued on March 19, 2002. Estimated Expiration Date: 
June 30, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 30, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSustained release capsule Controlled release formulations of Ranitidine Patent #: 5853756 InventorsAssigneeApplicationNo. 343425 filed on 06/30/1999US Classes:424/464, Tablets, lozenges, or pills424/435, Mouth424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/456, Gelatin424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/468, Sustained or differential release type424/474, Coated pills or tablets514/770, Siliceous or calcareous material (e.g., clay, earth, etc.)514/772.3, Solid synthetic organic polymer514/777, Carbohydrate or lignin, or derivative514/778, Starch or derivative514/779, Algin or derivative514/781, Cellulose or derivative514/782, Natural gum or resin514/784, Carboxylic acid or salt thereof514/937, DISPERSION OR EMULSION514/944GELExaminersPrimary: Spear, James M.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/20A61K 009/22 A61K 009/48 A61K 009/52 AbstractA pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is hydroxypropylcellulose (HPC) and the second component is at least one other polymer selected from the group consisting of methylcellulose (MC), ethylhydroxyethylcellulose (EHEC), hydroxyethylmethylcellulose (HEMC), hydrophobically modified hydroxyethylcellulose (HMHEC), hydrophobically modified ethylhydroxyethylcellulose (HMEHEC), carboxymethylhydroxyethylcellulose (CMHEC), carboxymethyl hydrophobically modified hydroxyethylcellulose (CMHMHEC), guar, pectin, carrageenan, agar, algin, gellan gum, acacia, starch and modified starches, co-polymers of carboxyvinyl monomers, co-polymers of acrylate or methacrylate monomers, mono- and co-polymers of oxyethylene and oxypropylene and mixtures thereof and a medicament in a sufficient amount to be therapeutic, with the proviso that low-substituted hydroxypropylcellulose (L-HPC) is excluded from said first and second components. The medicament can be a variety of drugs or nutritional supplements. The pharmaceutical composition releases the medicament for a prolonged or sustained period of time and can be formulated into many dosage forms.Field of SearchTablets, lozenges, or pillsSustained or differential release type Discrete particles in supporting matrix Coated pills or tablets Where particles are granulated Matrices Natural gums, resin or latex Synthetic polymer Acrylic acid and derivatives Polysaccharides (e.g., cellulose, etc.) Mouth Capsules (e.g., of gelatin, of chocolate, etc.) Gelatin | |
