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Antibody 97A6

Patent 6323321 Issued on November 27, 2001. Estimated Expiration Date: Icon_subject June 30, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventor

Assignee

Application

No. 344271 filed on 06/30/1999

US Classes:

530/387.2, Anti-idiotypic424/85.1, LYMPHOKINE424/93.1, WHOLE LIVE MICRO-ORGANISM, CELL, OR VIRUS CONTAINING424/94.1, ENZYME OR COENZYME CONTAINING424/130.1, IMMUNOGLOBULIN, ANTISERUM, ANTIBODY, OR ANTIBODY FRAGMENT, EXCEPT CONJUGATE OR COMPLEX OF THE SAME WITH NONIMMUNOGLOBULIN MATERIAL424/152.1, Binds eukaryotic cell or component thereof or substance produced by said eukaryotic cell424/178.1, CONJUGATE OR COMPLEX OF MONOCLONAL OR POLYCLONAL ANTIBODY, IMMUNOGLOBULIN, OR FRAGMENT THEREOF WITH NONIMMUNOGLOBULIN MATERIAL424/184.1, ANTIGEN, EPITOPE, OR OTHER IMMUNOSPECIFIC IMMUNOEFFECTOR (E.G., IMMUNOSPECIFIC VACCINE, IMMUNOSPECIFIC STIMULATOR OF CELL-MEDIATED IMMUNITY, IMMUNOSPECIFIC TOLEROGEN, IMMUNOSPECIFIC IMMUNOSUPPRESSOR, ETC.)424/277.1, Cancer cell or component thereof435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/5, Involving virus or bacteriophage435/6, Involving nucleic acid435/7.1, Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay435/7.21, Animal cell435/14, Involving glucose or galactose435/46, In presence of phenyl acetic acid or phenyl acetamide or their derivatives435/70.1, Using tissue cell culture to make a protein or polypeptide435/325, ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE436/95, Glucose436/119, SULFUR CONTAINING436/120, Organic or sulfhydryl containing (e.g., mercaptan, hydrogen, sulfide, etc.)436/169, With reagent in absorbent or bibulous substrate436/170, Plural superposed layers436/500, THYROID HORMONE TESTS (E.G., T3, T4, TBG, TSH, ETC.)436/805, OPTICAL PROPERTY436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY436/808, Automated or kit436/817, Steroids or hormones530/387.1Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or absorbed

Examiners

Primary: Chin, Christopher L.
Assistant: Cook, Lisa V.

Attorney, Agent or Firm

Foreign Patent References

  • 06141852A JP 05/22/1999

International Classes

A61K 039/395
C12N 005/20
G01N 033/574
G01N 033/577

Foreign Application Priority Data

1997-03-05 DE

Abstract

The present invention relates to a monoclonal antibody binding an antigen on the megakaryocytic cell line UT-7. The invention further relates to hybridoma cells producing such an antibody.

Other References

  • Harlow et al., "Labeling Antibodies", in, Antibodies: A Laboratory Manual. Chapter 9, pp. 319-3358, Jan. 1988.
  • Komatsu et al., Establishment and Characterization of a humna Leukemic cell line., Cancer Research, 51, 341-348, Jan. 1, 1991.
  • Yoshida et al., Studies on natral ST2 gene products in the humna leukemic cell line UT-7 using monoclonal antihuman st2 antibodies., Hybridoma, vol. 14, No. 5, 1995.
  • Wu et al., Indentification of IgG Fc receptor type II on humna megakaryoblastic cell lines., British Journal of Haematology, 1993, 84 pp.204-211.
  • Takafuta et al., Expression of platelet membrane glycoprotein V in humna magakaryocytes and megakayocytic cell lines., Thromb. Haemostasis., 1994, 72(5), 762-769.
  • Van den Oudenrijn et al., "Reactivity of the blind monoclonal antibody panel of the platelet section with megakaryocytic cell lines and cultured CD34 cells" Tissue Antigens-6th International workshop and conference on human leukocyte differentiation anti, Nov. 1996.
  • Van Den Oudenrijn S. et al., "Reactivity of the Blind Monoclonal Antibody Panel of the Platelet Section With Megakaryocytic Cell Lines and Cultured CD34+Cells" Tissue Antigens-6th International Workshop and Conference on Human Leukocyte Differentiation Antigens, Bd. 48, Nr. 4-2, 10.--(Nov. 14, 1996) Kobe Japan
  • Winderbank K. et al., Acute Megakaryocytic Leukemia (M7) in Childred, Mayo Clinical Proceedings, Bd. 64, Nr. 11, (1989) Seiten 1339-135
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