Patent ReferencesDetection of lung cancer using breath luminescence Method of detecting the presence of bronchogenic carcinoma by analysis of expired lung air Breath collection Breath test for detection of lung cancer Patent #: 5996586 InventorApplicationNo. 410870 filed on 10/01/1999US Classes:600/532, Qualitative or quantitative analysis of breath component128/206.29, Including means inserted in mouth128/898, Methods436/64CANCERExaminersPrimary: Winakur, Eric F.Assistant: Carter, Ryan Attorney, Agent or FirmInternational ClassA61B 005/08AbstractCarcinogenesis is accompanied by increased production of oxygen free radicals (OFRs) which degrade membranes by lipid peroxidation. The process evolves volatile organic compounds (VOCs), principally alkanes, which are excreted in the breath. VOCs in alveolar breath provided sensitive and specific markers of lung cancer. Breath VOC analysis is a non-invasive test which may potentially detect lung cancer at an early stage and reduce the high mortality of the disease. |
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