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Genipin derivative having liver protection activity

Patent 6262083 Issued on July 17, 2001. Estimated Expiration Date: Icon_subject May 5, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 530796 filed on 05/05/2000

US Classes:

514/337, The additional hetero ring is one of the cyclos in a polycyclo ring system514/338, Plural hetero atoms in the polycyclo ring system514/463, Plural ring oxygens in the hetero ring514/469, Bicyclo ring system having the hetero ring as one of the cyclos546/283.4, The additional hetero ring is five-membered546/283.7, Plural ring oxygens in the additional hetero ring546/284.1, Polycyclo ring system having the additional hetero ring as one of the cyclos549/387, Plural ring oxygens in the tricyclo ring system549/396Bicyclo ring system having the hetero ring as one of the cyclos

Examiners

Primary: Davis, Zinna Northington

Attorney, Agent or Firm

Foreign Patent References

  • A1 4323567 DE. 01/12/1994
  • 066682 JP 03/12/1991
  • A1 9817663 WO. 04/12/1998

International Classes

C07D 311/94
A61K 031/35

Foreign Application Priority Data

1997-11-05 KR

Abstract

The present invention relates to novel genipin derivatives which have an excellent liver protection activity with little cytotoxicity, and these compounds are so stable in vivo that they do not induce any side effects.

Other References

  • Bentley et al., Chem. Abstracts Citation of J. Chem. Soc. C, vol. 21, pp. 2234-2240, 196
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