Methods for in vitro susceptibility testing of chlamydia
Patent 6258532 Issued on July 10, 2001. Estimated Expiration Date: February 18, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
435/6, Involving nucleic acid435/7.36, Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)435/23, Involving proteinase435/32, Testing for antimicrobial activity of a material435/34, Determining presence or kind of micro-organism; use of selective media435/91.2, Acellular exponential or geometric amplification (e.g., PCR, etc.)536/23.7Encodes a microbial polypeptide
Methods for determining the susceptibility of intracellular pathogens, particularly Chlamydia, to single or combination of test agents are described. The methods can be used for in vitro or in vivo evaluation of agents that can be used as therapeutic agents in the treatment/eradication of pathogen infection in general or to target a specific infected organ. Assays which utilize nucleic amplification techniques (e.g., PCR) to determine effectiveness of the agent(s) evaluated are also described.
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