U.S. patents available from 1976 to present.
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Methods for in vitro susceptibility testing of chlamydia

Patent 6258532 Issued on July 10, 2001. Estimated Expiration Date: Icon_subject February 18, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventors

Assignee

Application

No. 025176 filed on 02/18/1998

US Classes:

435/6, Involving nucleic acid435/7.36, Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)435/23, Involving proteinase435/32, Testing for antimicrobial activity of a material435/34, Determining presence or kind of micro-organism; use of selective media435/91.2, Acellular exponential or geometric amplification (e.g., PCR, etc.)536/23.7Encodes a microbial polypeptide

Examiners

Primary: Myers, Carla J.
Assistant: Johannsen, Diana

Attorney, Agent or Firm

Foreign Patent References

  • 1 156 589 CN. 08/13/1997
  • 1 190 581 CN. 08/13/1998
  • 0439330 A2 EP. 01/13/1991
  • 0699688 A2 EP. 03/13/1996
  • 2 134 292 FR. 12/13/1972
  • WO 98 06435 WO. 02/13/1998
  • WO 98 10789 WO. 03/13/1998
  • WO 98 50074 WO. 11/13/1998
  • WO 00 01378 WO. 01/13/2012

International Classes

C12Q 001/68
C12Q 001/37
C12Q 001/18
G01N 033/571
C12P 019/34

Abstract

Methods for determining the susceptibility of intracellular pathogens, particularly Chlamydia, to single or combination of test agents are described. The methods can be used for in vitro or in vivo evaluation of agents that can be used as therapeutic agents in the treatment/eradication of pathogen infection in general or to target a specific infected organ. Assays which utilize nucleic amplification techniques (e.g., PCR) to determine effectiveness of the agent(s) evaluated are also described.

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