Pharmaceutical composition containing acid addition salt of basic drug
Patent 6255502 Issued on July 3, 2001. Estimated Expiration Date: 
April 19, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 19, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesReadily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof Patent #: 4722941 InventorsAssigneeApplicationNo. 225470 filed on 04/19/1999US Classes:552/549, Oxygen bonded directly at the 12-position (e.g., cholic acids, desoxycholic acids, dehydrocholic acids, etc.)424/550, Digestive system (e.g., salivary gland, etc.)424/551, Gastrointestinal system (e.g., intestine, stomach, gall bladder, etc.)424/553, Liver530/847, Bile552/550, Halogen, nitrogen, or sulfur containing (e.g., glycocholic acids, taurocholic acids, etc.)554/156Group IA or IIA metal containing reactant (e.g., forming a soap from fat and alkali, i.e., saponification, etc.)ExaminersPrimary: Carr, Deborah D.Attorney, Agent or FirmForeign Patent References
International ClassC07J 009/00Foreign Application Priority Data1996-07-11 ZAAbstractA pharmaceutical composition contains an acid addition salt of a basic drug and a fatty acid or bile acid. The acid addition salts thus formed exhibit enhanced transmucosal and transdermal penetration of the basic drug. The acid addition salts, an inclusion complex containing said salts and a use of said salts are also disclosed.Other References
Field of SearchGroup IA or IIA metal containing reactant (e.g., forming a soap from fat and alkali, i.e., saponification, etc.)Carboxylic acid or salt thereof PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED) Topical application Oxygen double bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system Digestive system (e.g., salivary gland, etc.) Gastrointestinal system (e.g., intestine, stomach, gall bladder, etc.) Liver Oxygen bonded directly at the 12-position (e.g., cholic acids, desoxycholic acids, dehydrocholic acids, etc.) Halogen, nitrogen, or sulfur containing (e.g., glycocholic acids, taurocholic acids, etc.) |
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