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US Patent 6251368 - Pharmaceutical aerosol formulation containing a particulate medicament, a propellant and substantially free of a surfactant
US Patent Issued on June 26, 2001
Estimated Patent Expiration Date:
June 17, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
June 17, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA pharmaceutical aerosol formulation which comprises particulate medicament selected from the group consisting of salmeterol, salbutamol, fluticasone propionate, beclomethasone dipropionate and physiologically acceptable salts and solvates thereof and a fluorocarbon or hydrogen-containing chlorofluorocarbon propellant, which formulation is substantially free of surfactant is disclosed. Also disclosed is a method of treating respiratory disorders which comprises administration by inhalation of an effective amount of the, pharmaceutical aerosol formulation which may be contained in a canister.Other References
| InventorsAssigneeApplicationNo. 877198 filed on 06/17/1997US Classes:424/45, Organic pressurized fluid424/46, Powder or dust containing514/937DISPERSION OR EMULSIONField of Search424/45, Organic pressurized fluid424/46, Powder or dust containing514/937DISPERSION OR EMULSIONExaminersPrimary: Bawa, RajAttorney, Agent or FirmUS Patent References2868691, 2885427, 3014844, 3219533, 3261748, 3320125, 3809294, 3897779, 4044126, Steroidal aerosol compositions and process for the preparation thereofIssued on: 08/23/1977 Inventor: Cook, et al.4174295, Aerosol propellant compositions Issued on: 11/13/1979 Inventor: Bargigia , et al.4347236, Process for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant Issued on: 08/31/1982 Inventor: Tanskanen4405598, Composition for treating asthma Issued on: 09/20/1983 Inventor: Brown4814161, Drug-containing chlorofluorocarbon aerosol propellent formulations Issued on: 03/21/1989 Inventor: Jinks , et al.4940171, Aerosol package having compressed gas propellant and vapor tap of minute size Issued on: 07/10/1990 Inventor: Gilroy 5118494, 5126123, Aerosol drug formulations Issued on: 06/30/1992 Inventor: Johnson5182097, Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content Issued on: 01/26/1993 Inventor: Byron, et al.5190029, Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content Issued on: 03/02/1993 Inventor: Byron, et al.5202110, Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants Issued on: 04/13/1993 Inventor: Dalby, et al.5225183, Medicinal aerosol formulations Issued on: 07/06/1993 Inventor: Purewal, et al.5230884, Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations Issued on: 07/27/1993 Inventor: Evans, et al.5348730, Method for preparing medicinal aerosol formulation containing coated medicament Issued on: 09/20/1994 Inventor: Greenleaf, et al.5605674, Medicinal aerosol formulations Issued on: 02/25/1997 Inventor: Purewal, et al.5653962, Aerosol formulations containing P134a and particulate medicaments Issued on: 08/05/1997 Inventor: Akehurst, et al.5658549, Aerosol formulations containing propellant 134a and fluticasone propionate Issued on: 08/19/1997 Inventor: Akehurst, et al.5674471, Aerosol formulations containing P134a and salbutamol Issued on: 10/07/1997 Inventor: Akehurst, et al.5674472, Canisters containing aerosol formulations containing P134a and fluticasone propionate Issued on: 10/07/1997 Inventor: Akehurst, et al.5674473, Medicinal aerosol formulations Issued on: 10/07/1997 Inventor: Purewal, et al.5676929, Canister containing aerosol formulations containing P134a and particulate medicaments Issued on: 10/14/1997 Inventor: Akehurst, et al.5681545, Medicinal aerosol formulations Issued on: 10/28/1997 Inventor: Purewal, et al.5683676, Canister containing aerosol formulations containing P134a and particulate medicaments Issued on: 11/04/1997 Inventor: Akehurst, et al.5683677, Medicinal aerosol formulations Issued on: 11/04/1997 Inventor: Purewal, et al.5688962, Cyclization process for making oxazolikinones Issued on: 11/18/1997 Inventor: Cox, et al.5695743, Medicinal aerosol formulations Issued on: 12/09/1997 Inventor: Purewal, et al.5744123, Aerosol formulations containing P134a and particulate medicaments Issued on: 04/28/1998 Inventor: Akehurst, et al.5833950, Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate Issued on: 11/10/1998 Inventor: Taylor, et al.5916540, Aerosol formulations containing P134A and/or P227 and particulate medicament Issued on: 06/29/1999 Inventor: Akehurst, et al.5922306Aerosol formulations containing P134a and particulate medicament Issued on: 07/13/1999 Inventor: Akehurst, et al. Foreign Patent References
International ClassA61K 009/12Foreign Application Priority Data1991-12-12 GB |
