Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
November 23, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesUnit dosage form of sparingly soluble medicaments Pharmaceutical compositions Drug in bead form and process for preparing same Aqueous dispersions of waxes and lipids for pharmaceutical coating Low solubility drug-coated bead compositions Chewable drug-delivery compositions and methods for preparing the same Redispersible nanoparticulate film matrices with protective overcoats Quick-dissolution solid preparation Beads having a core coated with an antifungal and a polymer Solid orally administerable raloxifene hydrochloride pharmaceutical formulation InventorsApplicationNo. 447690 filed on 11/23/1999US Classes:424/497, Containing solid synthetic polymers424/422, Implant or insert424/427, Ocular424/430, Vaginal, urethral, uterine424/433, Depot, pellet, matrix, or suppository424/434, Mucosal (e.g., nasal, etc.)424/435, Mouth424/436, Anal, rectal (e.g., suppositories, etc.)424/441, Chewable tablet or wafer424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/457, Sustained or differential release424/463, Coated capsules424/464, Tablets, lozenges, or pills424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/466, Effervescent424/470, Where particles are granulated424/474, Coated pills or tablets424/476, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate)424/482, Containing solid synthetic polymers424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof514/772.3, Solid synthetic organic polymer514/773, Peptide containing514/779, Algin or derivative514/784, Carboxylic acid or salt thereof514/785, Carboxylic acid ester514/786GlycerideExaminersPrimary: Spear, James M.Attorney, Agent or FirmInternational ClassesA61K 009/16A61K 009/28 A61K 009/32 A61K 009/52 A61K 009/56 A61K 009/58 427 430 434 441 466 474 AbstractThe present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one embodiment, the solid pharmaceutical composition includes a solid carrier, the solid carrier including a substrate and an encapsulation coat on the substrate. The encapsulation coat can include different combinations of pharmaceutical active ingredients, hydrophilic surfactant, lipophilic surfactants and triglycerides. In another embodiment, the solid pharmaceutical composition includes a solid carrier, the solid carrier being formed of different combinations of pharmaceutical active ingredients, hydrophilic surfactants, lipophilic surfactants and triglycerides. The compositions of the present invention can be used for improved delivery of hydrophilic or hydrophobic pharmaceutical active ingredients, such as drugs, nutrionals, cosmeceuticals and diagnostic agents.Field of SearchImplant or insertDepot, pellet, matrix, or suppository Anal, rectal (e.g., suppositories, etc.) Mouth Candy, candy coated or chewing gum Capsules (e.g., of gelatin, of chocolate, etc.) With claimed designated perfecting feature in contents (e.g., excipient, lubricant, etc.) Tablets, lozenges, or pills With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.) Containing solid synthetic polymers Particulate form (e.g., powders, granules, beads, microcapsules, and pellets) Coated (e.g., microcapsules) Cellulose or derivative Coated capsules Where particles are granulated Containing solid synthetic polymers Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate) | |
