U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Polynucleotide encoding insect ecdysone receptor

Patent 6245531 Issued on June 12, 2001. Estimated Expiration Date: Icon_subject June 12, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Recombinant cloning vehicle microbial polypeptide expression
Patent #: 4704362
Issued on: 11/03/1987
Inventor: Itakura ,   et al.

Auto-anti-idiotypic monoclonal antibodies to steroid receptors and uses thereof
Patent #: 4818684
Issued on: 04/04/1989
Inventor: Edelman ,   et al.

Polynucleotides encoding insect steroid hormone receptor polypeptides and cells transformed with same Patent #: 5514578
Issued on: 05/07/1996
Inventor: Hogness, et al.

Inventors

Assignee

Application

No. 08/465593 filed on 06/05/1995

US Classes:

435/69.7, Fusion proteins or polypeptides435/252.3, Transformants (e.g., recombinant DNA or vector or foreign or exogenous gene containing, fused bacteria, etc.)435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)435/325, ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE435/348, Insect cell, per se435/419, Plant cell or cell line, per se, contains exogenous or foreign nucleic acid435/69.1Recombinant DNA technique included in method of making a protein or polypeptide

Examiners

Primary: Pak, Michael

Attorney, Agent or Firm

International Classes

C07K 14/435 (20060101)
C07K 14/72 (20060101)
C07K 16/18 (20060101)
C07K 16/28 (20060101)
A61K 38/00 (20060101)

Abstract

Polynucleotide sequences which encode ecdysone receptors have been isolated and expressed in host cells.

Other References

  • Ashburner et al. (1974) Cold Spring Harbor Symp. Quant. Biol., 38:655-662. The Temporal Control of Puffing Activity in Polytene Chromosomes
  • Evans (1988) Science 240:889-895 The Steroid and Thyroid Hormone Receptor Superfamily
  • Green and Chambon (1988) Trends in Genetics 4:309-314 Nuclear Receptors Enhance Our Understanding of Transcription Regulation
  • Segraves (1988) Ph.D. Thesis, Stanford University Molecular and Genetic Analysis of the E75 Ecdysone-Responsive Gene of Drosophila melanogaster
  • Krust et al. (1986) EMBO J. 5:891-897 The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors
  • M. Kanehisa (1984) Nucleic Acids Res. 12:203-213 Use of statistical criteria for screening potential homologies in nucleic acid sequences
  • Hershko and Ciechanover (1982) Ann. Rev. Bioch. 51:335-364 Mechanisms of Intracellular Protein Breakdown
  • Miller et al. (1985) EMBO J. 4:1609-1614 Receptor zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
  • Freedman et al. (1988) Nature 334:543-546 The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain
  • Severne et al. (1988) EMBO J. 9:2503-2508 Metal binding "finger" structures in the glucocorticoid receptor defined by site-directed mutagenesis
  • Giguere et al. (1986) Cell 46:645-652 Functional Domains of the Human Glucocorticoid Receptor
  • Danielson et al. (1987) Mol. Endocrinol. 1:816-822 Domains of the Glucocorticoid Receptor Involved in Specific and Nonspecific Deoxyribonucleic Acid Binding, Hormone Activation, and Transcriptional Enhancement
  • Rusconi et al. (1987) EMBO J. 6:1309-1315 Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor
  • Mader et al. (1989) Nature 338:271-274 Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element
  • Umesono and Evans (1989) Cell 57:1139-46 Determinants of Target Gene Specificity for Steroid/Thyroid Hormone Receptors
  • Umesono et al (1988) Nature 336:262-265 Retinoic acid and thyroid hormone induce gene expression through a common responsive element
  • Kumar and Chambon (1988) Cell 55:145-156 The Estrogen Receptor Binds Tightly to Its Responsive Element as a Ligand-Induced Homodimer
  • Guiochon et al. (1989) Cell 57:1147-1154 Mechanisms of Nuclear Localization of the Progesterone Receptor: Evidence for Interaction between Monomers
  • Picard and Yamamoto (1987) EMBO J. 6:3333-3340 Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
  • Pratt et al. (1988) J. Biol. Chem. 263:267-273 A Region in the Steroid Binding Domain Determines Formation of the Non-DNA-binding, 9 S Glucocorticoid Receptor Complex
  • Nauber et al. (1988) Nature 336:489-492 Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps
  • Oro et al. (1988) Nature 336:493-496 The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily
  • Rothe et al. (1989) EMBO J. 8:3087-3094 Three hormone receptor-like Drosophila genes encode an identical DNA-binding finger
  • Petkovich et al. (1987) Nature 330:444-450 A human retinoic acid receptor which belongs to the family of nuclear receptors
  • Dieckmann and Tzagaloff (1985) J. Biol. Chem. 260:1513-1520 Assembly of the Mitochondrial Membrane System
  • Riddihough and Pelham (1987) EMBO J. 6:3729-3734 An ecdysone response element in the Drosophila hsp27 promoter
  • Strangmann-Diekann et al. (1990) Eur. J. Biochem. 189:137-143. Affinity Labelling of Partially Purified Ecdysteroid Receptor with Bromoacetylated 20-OH-ecdysone Derivative
  • Lehmann et al. (1988) Molecular and Cellular Endocrinology 57:239-249 Ecdysteroid Receptors of the blowfly
  • Poole et al. (1985) Cell 40:37-40 The engrailed Locus of Drosophila: Structural Analysis of an Embryonic Transcript
  • Feigl et al. (1989) Nucleic Acids Research 17(18):7167-7178 A member of the steroid hormone receptor gene family is expressed in the 20-OH-ecdysone inducible puff 75B in Drosophila melanogaster
  • Ronald M. Evans (1988) Science 240:889-895 The Steroid and Thyroid Hormone Receptor Superfamily
  • Bidmon and Koolman (1989) Experientia 45:106-109 Ecdysteroid receptors located in the central nervous system of an insect
  • Meyerowitz and Hogness (1982) Cell 28:165-176 Molecular Organization of a Drosophila Puff Site That Responds to Ecdysone
  • G. Reeck et al. (1987) Cell 50:667. "Homology" in Proteins and Nucleic Acids: A Terminology Muddle and A Way out of It
  • Suggs et al. (1981) PNAS 78:6613-6617. Use of synthetic oligonucleotides as hybridization probes: Isolation of cloned cDNA sequences for human ଲ2 -microglobulin
  • George et al. (1988) Macromolecular Sequencing and Synthesis (Ed. by D.H. Schlesinger) Alan R. Liss, Inc., New York, pp. 127-149.
  • Maniatis et al. (1978) Cell 15:687-701.
  • Bowie et al. (1990) Science 247:1307-1310.
  • Koelle et al. (1991) Cell 67:59-77.
  • Pardue (1986) Drosophila a practical approach (Ed. by D.B. Roberts) IRL Press Limited, Oxord, pp. 111-136.
  • Jowlett (1986) Drosophila A Practical Approach (Ed. by D.B. Roberts) IRL Press Limited, Oxford, pp. 275-286
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
 
Sign InRegister
Username  
Password   
forgot password?