Method and apparatus for noninvasive measurement of carotenoids and related chemical substances in biological tissue
June 18, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3563233 Device and method for noresonantly Raman shifting ultraviolet radiation Optically pumped isotopic ammonia laser system Bromine anti-stokes raman laser Method for stimulating salivation High potential generating toothbrush Control of laser photocoagulation using Raman radiation Frequency adding lasers and optical amplifiers Method of using resonance raman spectroscopy for detection of malignancy disease Photocharacterization and treatment of normal abnormal and ectopic endometrium InventorsApplicationNo. 335932 filed on 06/18/1999US Classes:600/477, With comparison means (e.g., ratio of or comparison to a standard)356/301With Raman type light scatteringExaminersPrimary: Casler, Brian L.Attorney, Agent or FirmForeign Patent References
International ClassA61B 006/00AbstractA method and apparatus are provided for the determination of levels of carotenoids and similar chemical compounds in biological tissue such as living skin. The method and apparatus provide a noninvasive, rapid, accurate, and safe determination of carotenoid levels which in turn can provide diagnostic information regarding cancer risk, or can be a marker for conditions where carotenoids or other antioxidant compounds may provide diagnostic information. Such early diagnostic information allows for the possibility of preventative intervention. The method and apparatus utilize the technique of resonance Raman spectroscopy to measure the levels of carotenoids and similar substances in tissue. In this technique, laser light is directed upon the area of tissue which is of interest. A small fraction of the scattered light is scattered inelastically, producing the carotenoid Raman signal which is at a different frequency than the incident laser light, and the Raman signal is collected, filtered, and measured. The resulting Raman signal can be analyzed such that the background fluorescence signal is subtracted and the results displayed and compared with known calibration standards.Other References
Field of SearchInfrared radiationVisible light radiation With comparison means (e.g., ratio of or comparison to a standard) With comparison means (e.g., ratio of or comparison to a standard) Infrared, visible light, or ultraviolet radiation directed on or through body or constituent released therefrom Determining constituents in eye With Raman type light scattering With spectral analysis Light application Lithotripsy With particular wavelength Ophthalmic Systems | |
