Patent 6204268 Issued on March 20, 2001. Estimated Expiration Date: April 13, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/254.02, The additional five-membered hetero ring also has chalcogen as a ring member514/64, Boron containing DOAI514/211.15, Additional nitrogen containing hetero ring attached directly or indirectly to the seven-membered hetero ring by nonionic bonding514/217.05, Plural ring hetero atoms in the additional hetero ring514/235.8, Plural ring nitrogens in the additional hetero ring (e.g., imidazole, pyrazine, etc.)514/253.1, The five-membered nitrogen hetero ring has chalcogen as a ring member540/598, Plural hetero atoms in the additional hetero ring544/121, Piperazine ring544/229, Boron or silicon containing544/357, Plural diazine rings544/360, Six-membered ring consisting of one nitrogen and five carbons (e.g., pyridine, etc.)544/363, Quinoline or isoquinoline (including hydrogenated)544/364, At least three hetero rings containing544/368, The five-membered hetero ring is one of the cyclos in a polycyclo ring system544/369, 1,3-oxazole ring or 1,3-thiazole ring (including hydrogenated)544/384, Chalcogen bonded directly to piperazine ring carbon544/385Plural chalcogens bonded directly to piperazine ring carbons
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
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