Method and apparatus for monitoring a magnetic resonance image during transcranial magnetic stimulation
Patent 6198958 Issued on March 6, 2001. Estimated Expiration Date: June 11, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
A method and apparatus for monitoring a magnetic resonance image of a patient during administration of transcranial magnetic stimulation. The method includes the steps of applying transcranial magnetic stimulation (TMS) to a patient using a probe that is substantially constructed of non-ferromagnetic material, monitoring a magnetic resonance image (MRI) of the patient during TMS wherein application of the TMS does not need to by synchronized to monitoring of the MRI.
Other References
International Search Report from International Patent Application PCT/US99/08489, filed Apr. 22, 1999
International Search Report from International Patent Application PCT/US99/13051, filed Jun. 9, 1999
Ilmoniemi RJ, Virtanen J: "Neuronal reposnses to magnetic stimulation reveal cortical reactivity and connectivity ", NeuroReport, vol. 8, No. 16, Nov. 10, 1997, pp. 3537-3540
Ruohonen J: "Transcranical Magnetic Stimulation: Modelling and New Techniques" Dissertation, Department of Engineering Physics and Mathematics Laboratory of Biomedical Engineering Helsinki University of Technology, Dec. 4, 1998, p. 28, paragraph 2; p. 30, paragraph 1; figure 6
Bohning, D: "Interleaved Transcranial Magnetic Stimulation (TMS) and fMRI", proceedings of the international society for magnetic resonance in medicine, Sixth Scientific Meeting and Exhibition, Sydney, Australia Apr. 18-24, 1998, vol. 1. p. 508
Bohning, D: "Echoplanar Bold fMRI of Brain Activation Induced by Concurrent Transcranial Magnetic Stimulation", Investigative Radiology, vol. 33, No. 6, Jun 1998, pp 336-340
Bohning, D: "Mapping transcranial magnetic stimulation (TMS) fields in vivo with MRI", Neuroreport, vol. 8, No. 11, 1997, pp. 2535-2538
Pascual-Leone, A, et al.: "Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Motor Cortex Activity During a Rate Controlled Motor Task as Measured by Functional Magnetic Resonance Imaging (fMRI)", Neurology, vol. 48, No. 3, (supp. 2), 1997, p. A10
June 11, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
