U.S. patents available from 1976 to present.
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Combination therapy including 9-nitro-20(S)-camptothecin

Patent 6191119 Issued on February 20, 2001. Estimated Expiration Date: Icon_subject October 15, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Camptothecin drug combinations and methods with reduced side effects Patent #: 5786344
Issued on: 07/28/1998
Inventor: Ratain, et al.

Inventor

Assignee

Application

No. 418862 filed on 10/15/1999

US Classes:

514/34, Oxygen of the saccharide radical bonded directly to a polycyclo ring system of four carbocyclic rings (e.g., daunomycin, etc.)514/283Ring nitrogen in the pentacyclo ring system is shared by five-membered cyclo and six-membered cyclo (e.g., vincamine, etc.)

Examiners

Primary: Goldberg, Jerome D.

Attorney, Agent or Firm

International Classes

A61K 031/70
A61K 031/44

Abstract

A method for treating a patient having a disease associated with undesirable or uncontrolled cell proliferation such as cancer and restenosis is provided. The method comprises: delivering to the patient a therapeutically effective amount of 9-nitro-20(S)-camptothecin in combination with an effective amount of an antibiotic agent such as doxorubicin.

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